Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation von Hubatsch, I, Ridderström, M, Mannervik, B

Volltext

Analysis of Selective Regions in the Active Sites of Human Cytochromes P450, 2C8, 2C9, 2C18, and 2C19 Homology Models Using GRID/CPCA von Ridderström, Marianne, Zamora, Ismael, Fjellström, Ola, Andersson, Tommy B

Volltext

Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue von Cameron, Alexander D, Ridderström, Marianne, Olin, Birgit, Mannervik, Bengt

Volltext

Competitive CYP2C9 Inhibitors: Enzyme Inhibition Studies, Protein Homology Modeling, and Three-Dimensional Quantitative Structure-Activity Relationship Analysis von Afzelius, Lovisa, Zamora, Ismael, Ridderström, Marianne, Andersson, Tommy B., Karlén, Anders, Masimirembwa, Collen M.

Volltext

Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products von Bruns, Christopher M, Hubatsch, Ina, Ridderström, Marianne, Mannervik, Bengt, Tainer, John A

Volltext

Reaction Mechanism of Glyoxalase I Explored by an X-ray Crystallographic Analysis of the Human Enzyme in Complex with a Transition State Analogue von Cameron, Alexander D, Ridderström, Marianne, Olin, Birgit, Kavarana, Malcolm J, Creighton, Donald J, Mannervik, Bengt

Volltext

An ultrafast system for signaling mechanical pain in human skin von Nagi, Saad S, Marshall, Andrew G, Makdani, Adarsh, Jarocka, Ewa, Liljencrantz, Jaquette, Ridderström, Mikael, Shaikh, Sumaiya, O'Neill, Francis, Saade, Dimah, Donkervoort, Sandra, Foley, A Reghan, Minde, Jan, Trulsson, Mats, Cole, Jonathan, Bönnemann, Carsten G, Chesler, Alexander T, Bushnell, M Catherine, McGlone, Francis, Olausson, Håkan

Volltext

Arginines 97 and 108 in CYP2C9 Are Important Determinants of the Catalytic Function von Ridderström, Marianne, Masimirembwa, Collen, Trump-Kallmeyer, Susanne, Ahlefelt, Maria, Otter, Charlotta, Andersson, Tommy B.

Volltext

CYP2C9 Structure−Metabolism Relationships:  Optimizing the Metabolic Stability of COX-2 Inhibitors von Ahlström, Marie M, Ridderström, Marianne, Zamora, Ismael, Luthman, Kristina

Volltext

Molecular cloning and characterization of the thiolesterase glyoxalase II from Arabidopsis thaliana von Ridderström, M, Mannervik, B

Volltext

The primary structure of monomeric yeast glyoxalase I indicates a gene duplication resulting in two similar segments homologous with the subunit of dimeric human glyoxalase I von Ridderström, M, Mannervik, B

Volltext

Optimized heterologous expression of the human zinc enzyme glyoxalase I von Ridderström, M, Mannervik, B

Volltext

Brilliant blue G treatment facilitates regeneration after optic nerve injury in the adult rat von Ridderström, Mikael, Ohlsson, Marcus

Volltext

Molecular Cloning, Heterologous Expression, and Characterization of Human Glyoxalase II (∗) von Ridderström, Marianne, Saccucci, Franca, Hellman, Ulf, Bergman, Tomas, Principato, Giovanni, Mannervik, Bengt

Volltext

The Human Glutathione Transferase P1-1 Specific Inhibitor TER 117 Designed for Overcoming Cytostatic-Drug Resistance Is also a Strong Inhibitor of Glyoxalase I von Johansson, Ann-Sofie, Ridderström, Marianne, Mannervik, Bengt

Volltext

Combining pharmacophore and protein modeling to predict CYP450 inhibitors and substrates von Masimirembwa, Collen M., Ridderström, Marianne, Zamora, Ismael, Andersson, Tommy B.

Volltext

Mutagenesis of residue 157 in the active site of human glyoxalase I von Ridderström, M, Cameron, A D, Jones, T A, Mannervik, B

Volltext

Crystal structure of human glyoxalase I-evidence for gene duplication and 3D domain swapping von Cameron, Alexander D., Olin, Birgit, Ridderström, Marianne, Mannervik, Bengt, Jones, T.Alwyn

Volltext

Unfolding and Refolding of Human Glyoxalase II and its Single-tryptophan Mutants von Dragani, Beatrice, Cocco, Roberta, Ridderström, Marianne, Stenberg, Gun, Mannervik, Bengt, Aceto, Antonio

Volltext

Cloning and heterologous expression of cDNA encoding class alpha rat glutathione transferase 8-8, an enzyme with high catalytic activity towards genotoxic α,β-unsaturated carbonyl... von STENBERG, G, RIDDERSTRÖM, M, ENGSTRÖM, A, PEMBLE, S. E, MANNERVIK, B

Volltext