The Cancer Genome Atlas of renal cell carcinoma: findings and clinical implications von Linehan, W. Marston, Ricketts, Christopher J.

Volltext

The Metabolic Basis of Kidney Cancer von Linehan, W Marston, Schmidt, Laura S, Crooks, Daniel R, Wei, Darmood, Srinivasan, Ramaprasad, Lang, Martin, Ricketts, Christopher J

Volltext

Gender Specific Mutation Incidence and Survival Associations in Clear Cell Renal Cell Carcinoma (CCRCC) von Ricketts, Christopher J, Linehan, W Marston

Volltext

Chromosome 3p Loss-Orchestrated VHL, HIF, and Epigenetic Deregulation in Clear Cell Renal Cell Carcinoma von Hsieh, James J, Le, Valerie H, Oyama, Toshinao, Ricketts, Christopher J, Ho, Thai Huu, Cheng, Emily H

Volltext

New strategies in renal cell carcinoma: targeting the genetic and metabolic basis of disease von Srinivasan, Ramaprasad, Ricketts, Christopher J, Sourbier, Carole, Linehan, W Marston

Volltext

Tumor-specific hypermethylation of epigenetic biomarkers, including SFRP1, predicts for poorer survival in patients from the TCGA Kidney Renal Clear Cell Carcinoma (KIRC) project von Ricketts, Christopher J, Hill, Victoria K, Linehan, W Marston

Volltext

Defining Early-Onset Kidney Cancer: Implications for Germline and Somatic Mutation Testing and Clinical Management von SHUCH, Brian, VOURGANTI, Srinivas, RICKETTS, Christopher J, MIDDLETON, Lindsay, PETERSON, James, MERINO, Maria J, METWALLI, Adam R, SRINIVASAN, Ramaprasad, LINEHAN, W. Marston

Volltext

Targeting ABL1-Mediated Oxidative Stress Adaptation in Fumarate Hydratase-Deficient Cancer von Sourbier, Carole, Ricketts, Christopher J., Matsumoto, Shingo, Crooks, Daniel R., Liao, Pei-Jyun, Mannes, Philip Z., Yang, Youfeng, Wei, Ming-Hui, Srivastava, Gaurav, Ghosh, Sanchari, Chen, Viola, Vocke, Cathy D., Merino, Maria, Srinivasan, Ramaprasad, Krishna, Murali C., Mitchell, James B., Pendergast, Ann Marie, Rouault, Tracey A., Neckers, Len, Linehan, W. Marston

Volltext

Intratumoral heterogeneity in kidney cancer von Ricketts, Christopher J, Linehan, W Marston

Volltext

Kidney tumors associated with germline mutations of FH and SDHB show a CpG island methylator phenotype (CIMP) von Ricketts, Christopher J, Killian, J Keith, Vocke, Cathy D, Wang, Yonghong, Merino, Maria J, Meltzer, Paul S, Linehan, W Marston

Volltext

Clinical and Molecular Characterization of Microphthalmia-associated Transcription Factor (MITF)-related Renal Cell Carcinoma von Lang, Martin, Vocke, Cathy D., Ricketts, Christopher J., Metwalli, Adam R., Ball, Mark W., Schmidt, Laura S., Linehan, William M.

Volltext

Growth Rates of Genetically Defined Renal Tumors: Implications for Active Surveillance and Intervention von Ball, Mark W., An, Julie Y., Gomella, Patrick T., Gautam, Rabindra, Ricketts, Christopher J., Vocke, Cathy D., Schmidt, Laura S., Merino, Maria J., Srinivasan, Ramaprasad, Malayeri, Ashkan A., Metwalli, Adam R., Linehan, W. Marston

Volltext

Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase-deficient renal cancer von Crooks, Daniel R., Maio, Nunziata, Lang, Martin, Ricketts, Christopher J., Vocke, Cathy D., Gurram, Sandeep, Turan, Sevilay, Kim, Yun-Young, Cawthon, G. Mariah, Sohelian, Ferri, De Val, Natalia, Pfeiffer, Ruth M., Jailwala, Parthav, Tandon, Mayank, Tran, Bao, Fan, Teresa W-M, Lane, Andrew N., Ried, Thomas, Wangsa, Darawalee, Malayeri, Ashkan A., Merino, Maria J., Yang, Youfeng, Meier, Jordan L., Ball, Mark W., Rouault, Tracey A., Srinivasan, Ramaprasad, Linehan, W. Marston

Volltext

Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility von Astuti, Dewi, Morris, Mark R, Cooper, Wendy N, Staals, Raymond H J, Wake, Naomi C, Fews, Graham A, Gill, Harmeet, Gentle, Dean, Shuib, Salwati, Ricketts, Christopher J, Cole, Trevor, van Essen, Anthonie J, van Lingen, Richard A, Neri, Giovanni, Opitz, John M, Rump, Patrick, Stolte-Dijkstra, Irene, Müller, Ferenc, Pruijn, Ger J M, Latif, Farida, Maher, Eamonn R

Volltext

Targeting HIF2α in Clear-Cell Renal Cell Carcinoma von Ricketts, Christopher J., Crooks, Daniel R., Linehan, W. Marston

Volltext

Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma von Yang, Youfeng, Lane, Andrew N, Ricketts, Christopher J, Sourbier, Carole, Wei, Ming-Hui, Shuch, Brian, Pike, Lisa, Wu, Min, Rouault, Tracey A, Boros, Laszlo G, Fan, Teresa W-M, Linehan, W Marston

Volltext

Unbiased discovery of cancer pathways and therapeutics using Pathway Ensemble Tool and Benchmark von Wang, Luopin, Pattnaik, Aryamav, Sahoo, Subhransu Sekhar, Stone, Ella G., Zhuang, Yuxin, Benton, Annaleigh, Tajmul, Md, Chakravorty, Srishti, Dhawan, Deepika, Nguyen, My An, Sirit, Isabella, Mundy, Kyle, Ricketts, Christopher J., Hadisurya, Marco, Baral, Garima, Tinsley, Samantha L., Anderson, Nicole L., Hoda, Smriti, Briggs, Scott D., Kaimakliotis, Hristos Z., Allen-Petersen, Brittany L., Tao, W. Andy, Linehan, W. Marston, Knapp, Deborah W., Hanna, Jason A., Olson, Matthew R., Afzali, Behdad, Kazemian, Majid

Volltext

TFEB and TFE3 drive kidney cystogenesis and tumorigenesis von Di Malta, Chiara, Zampelli, Angela, Granieri, Letizia, Vilardo, Claudia, De Cegli, Rossella, Cinque, Laura, Nusco, Edoardo, Pece, Salvatore, Tosoni, Daniela, Sanguedolce, Francesca, Sorrentino, Nicolina Cristina, Merino, Maria J, Nielsen, Deborah, Srinivasan, Ramaprasad, Ball, Mark W, Ricketts, Christopher J, Vocke, Cathy D, Lang, Martin, Karim, Baktiar, Lanfrancone, Luisa, Schmidt, Laura S, Linehan, W Marston, Ballabio, Andrea

Volltext

The Genetic Basis of Pheochromocytoma and Paraganglioma: Implications for Management von Shuch, Brian, Ricketts, Christopher J, Metwalli, Adam R, Pacak, Karel, Linehan, W. Marston

Volltext

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma von Ricketts, Christopher J., De Cubas, Aguirre A., Fan, Huihui, Smith, Christof C., Lang, Martin, Reznik, Ed, Bowlby, Reanne, Gibb, Ewan A., Akbani, Rehan, Beroukhim, Rameen, Bottaro, Donald P., Choueiri, Toni K., Gibbs, Richard A., Godwin, Andrew K., Haake, Scott, Hakimi, A. Ari, Henske, Elizabeth P., Hsieh, James J., Ho, Thai H., Kanchi, Rupa S., Krishnan, Bhavani, Kwiatkowski, David J., Liu, Wenbin, Merino, Maria J., Mills, Gordon B., Myers, Jerome, Nickerson, Michael L., Reuter, Victor E., Schmidt, Laura S., Shelley, C. Simon, Shen, Hui, Shuch, Brian, Signoretti, Sabina, Srinivasan, Ramaprasad, Tamboli, Pheroze, Thomas, George, Vincent, Benjamin G., Vocke, Cathy D., Wheeler, David A., Yang, Lixing, Kim, William Y., Robertson, A. Gordon, Spellman, Paul T., Rathmell, W. Kimryn, Linehan, W. Marston

Volltext