Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration von Raven, Alexander, Lu, Wei-Yu, Man, Tak Yung, Ferreira-Gonzalez, Sofia, O’Duibhir, Eoghan, Dwyer, Benjamin J., Thomson, John P., Meehan, Richard R., Bogorad, Roman, Koteliansky, Victor, Kotelevtsev, Yuri, ffrench-Constant, Charles, Boulter, Luke, Forbes, Stuart J.

Volltext

Rett syndrome: interferon-γ to the rescue? von Meehan, Richard R, Pennings, Sari

Volltext

Toll-like receptor 7 (TLR7)–driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity von Rubtsov, Anatoly V., Rubtsova, Kira, Fischer, Aryeh, Meehan, Richard T., Gillis, Joann Z., Kappler, John W., Marrack, Philippa

Volltext

Non-canonical functions of the DNA methylome in gene regulation von Reddington, James P, Pennings, Sari, Meehan, Richard R

Volltext

Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA von Nestor, Colm, Ruzov, Alexey, Meehan, Richard R, Dunican, Donncha S

Volltext

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes von Nestor, Colm E, Ottaviano, Raffaele, Reddington, James, Sproul, Duncan, Reinhardt, Diana, Dunican, Donncha, Katz, Elad, Dixon, J Michael, Harrison, David J, Meehan, Richard R

Volltext

Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions von Cole, John J, Robertson, Neil A, Rather, Mohammed Iqbal, Thomson, John P, McBryan, Tony, Sproul, Duncan, Wang, Tina, Brock, Claire, Clark, William, Ideker, Trey, Meehan, Richard R, Miller, Richard A, Brown-Borg, Holly M, Adams, Peter D

Volltext

DNA methylation as a genomic marker of exposure to chemical and environmental agents von Meehan, Richard R, Thomson, John P, Lentini, Antonio, Nestor, Colm E, Pennings, Sari

Volltext

Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems von Nestor, Colm E, Ottaviano, Raffaele, Reinhardt, Diana, Cruickshanks, Hazel A, Mjoseng, Heidi K, McPherson, Rhoanne C, Lentini, Antonio, Thomson, John P, Dunican, Donncha S, Pennings, Sari, Anderton, Stephen M, Benson, Mikael, Meehan, Richard R

Volltext

Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline von Crichton, James H, Dunican, Donncha S, MacLennan, Marie, Meehan, Richard R, Adams, Ian R

Volltext

Loss of the maintenance methyltransferase, xDnmt1, induces apoptosis in Xenopus embryos von Stancheva, Irina, Hensey, Carmel, Meehan, Richard R

Volltext

Shoring up DNA methylation and H3K27me3 domain demarcation at developmental genes von Meehan, Richard R, Pennings, Sari

Volltext

Genomic insights into cancer-associated aberrant CpG island hypermethylation von Sproul, Duncan, Meehan, Richard R

Volltext

Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group trial von Tashkin, Donald P, Prof, Roth, Michael D, Prof, Clements, Philip J, Prof, Furst, Daniel E, Prof, Khanna, Dinesh, Prof, Kleerup, Eric C, Prof, Goldin, Jonathan, Prof, Arriola, Edgar, PharmD, Volkmann, Elizabeth R, MD, Kafaja, Suzanne, MD, Silver, Richard, Prof, Steen, Virginia, Prof, Strange, Charlie, Prof, Wise, Robert, Prof, Wigley, Fredrick, Prof, Mayes, Maureen, Prof, Riley, David J, Prof, Hussain, Sabiha, MD, Assassi, Shervin, MD, Hsu, Vivien M, MD, Patel, Bela, MD, Phillips, Kristine, MD, Martinez, Fernando, Prof, Golden, Jeffrey, Prof, Connolly, M Kari, Prof, Varga, John, Prof, Dematte, Jane, Prof, Hinchcliff, Monique E, MD, Fischer, Aryeh, MD, Swigris, Jeffrey, DO, Meehan, Richard, MD, Theodore, Arthur, Prof, Simms, Robert, Prof, Volkov, Suncica, MD, Schraufnagel, Dean E, Prof, Scholand, Mary Beth, MD, Frech, Tracy, MD, Molitor, Jerry A, Prof, Highland, Kristin, MD, Read, Charles A, Prof, Fritzler, Marvin J, Prof, Kim, Grace Hyun J, PhD, Tseng, Chi-Hong, PhD, Elashoff, Robert M, Prof

Volltext

Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes von Reddington, James P, Perricone, Sara M, Nestor, Colm E, Reichmann, Judith, Youngson, Neil A, Suzuki, Masako, Reinhardt, Diana, Dunican, Donncha S, Prendergast, James G, Mjoseng, Heidi, Ramsahoye, Bernard H, Whitelaw, Emma, Greally, John M, Adams, Ian R, Bickmore, Wendy A, Meehan, Richard R

Volltext

DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency von McLaughlin, Katy, Flyamer, Ilya M., Thomson, John P., Mjoseng, Heidi K., Shukla, Ruchi, Williamson, Iain, Grimes, Graeme R., Illingworth, Robert S., Adams, Ian R., Pennings, Sari, Meehan, Richard R., Bickmore, Wendy A.

Volltext

Senescent cells harbour features of the cancer epigenome von Cruickshanks, Hazel A., McBryan, Tony, Nelson, David M., VanderKraats, Nathan D., Shah, Parisha P., van Tuyn, John, Singh Rai, Taranjit, Brock, Claire, Donahue, Greg, Dunican, Donncha S., Drotar, Mark E., Meehan, Richard R., Edwards, John R., Berger, Shelley L., Adams, Peter D.

Volltext

Modules, networks and systems medicine for understanding disease and aiding diagnosis von Gustafsson, Mika, Nestor, Colm E, Zhang, Huan, Barabási, Albert-László, Baranzini, Sergio, Brunak, Sören, Chung, Kian Fan, Federoff, Howard J, Gavin, Anne-Claude, Meehan, Richard R, Picotti, Paola, Pujana, Miguel Àngel, Rajewsky, Nikolaus, Smith, Kenneth Gc, Sterk, Peter J, Villoslada, Pablo, Benson, Mikael

Volltext

Bivalent promoter hypermethylation in cancer is linked to the H327me3/H3K4me3 ratio in embryonic stem cells von Dunican, Donnchadh S, Mjoseng, Heidi K, Duthie, Leanne, Flyamer, Ilya M, Bickmore, Wendy A, Meehan, Richard R

Volltext

Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis von Sadiku, Pranvera, Willson, Joseph A., Ryan, Eilise M., Sammut, David, Coelho, Patricia, Watts, Emily R., Grecian, Robert, Young, Jason M., Bewley, Martin, Arienti, Simone, Mirchandani, Ananda S., Sanchez Garcia, Manuel A., Morrison, Tyler, Zhang, Ailing, Reyes, Leila, Griessler, Tobias, Jheeta, Privjyot, Paterson, Gordon G., Graham, Christopher J., Thomson, John P., Baillie, Kenneth, Thompson, A.A. Roger, Morgan, Jessie-May, Acosta-Sanchez, Abel, Dardé, Veronica M., Duran, Jordi, Guinovart, Joan J., Rodriguez-Blanco, Gio, Von Kriegsheim, Alex, Meehan, Richard R., Mazzone, Massimiliano, Dockrell, David H., Ghesquiere, Bart, Carmeliet, Peter, Whyte, Moira K.B., Walmsley, Sarah R.

Volltext