Four Lessons from Global Health Drug Discovery: Medicine for an Ailing Industry? von Elliott, Richard L

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Discovery of Spiro-azaindoline Inhibitors of Hematopoietic Progenitor Kinase 1 (HPK1) von Chan, Bryan K, Seward, Eileen, Lainchbury, Michael, Brewer, Thomas F, An, Le, Blench, Toby, Cartwright, Matthew W, Chan, Grace Ka Yan, Choo, Edna F, Drummond, Jason, Elliott, Richard L, Gancia, Emanuela, Gazzard, Lewis, Hu, Baihua, Jones, Graham E, Luo, Xifeng, Madin, Andrew, Malhotra, Sushant, Moffat, John G, Pang, Jodie, Salphati, Laurent, Sneeringer, Christopher J, Stivala, Craig E, Wei, Binqing, Wang, Weiru, Wu, Ping, Heffron, Timothy P

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Cascade Palladium-Catalyzed Direct Intramolecular Arylation/Alkene Isomerization Sequences: Synthesis of Indoles and Benzofurans von Yagoubi, Myriam, Cruz, Ana C.F, Nichols, Paula L, Elliott, Richard L, Willis, Michael C

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Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor von Chan, Bryan K, Hanan, Emily J, Bowman, Krista K, Bryan, Marian C, Burdick, Daniel, Chan, Emily, Chen, Yuan, Clausen, Saundra, Dela Vega, Trisha, Dotson, Jennafer, Eigenbrot, Charles, Elliott, Richard L, Heald, Robert A, Jackson, Philip S, Knight, Jamie D, La, Hank, Lainchbury, Michael D, Malek, Shiva, Purkey, Hans E, Schaefer, Gabriele, Schmidt, Stephen, Seward, Eileen M, Sideris, Steve, Shao, Lily, Wang, Shumei, Yeap, Siew Kuen, Yen, Ivana, Yu, Christine, Heffron, Timothy P

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The role of modern drug discovery in the fight against neglected and tropical diseases von Burrows, Jeremy N, Elliott, Richard L, Kaneko, Takushi, Mowbray, Charles E, Waterson, David

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Functional Characterization of the Novel Neuronal Nicotinic Acetylcholine Receptor Ligand GTS-21 In Vitro and In Vivo von Briggs, Clark A, Anderson, David J, Brioni, Jorge D, Buccafusco, Jerry J, Buckley, Michael J, Campbell, Jeffrey E, Decker, Michael W, DONNELLY–ROBERTS, Diana, Elliott, Richard L, Gopalakrishnan, Murali, Holladay, Mark W, Hui, Yu-Hua, Jackson, William J, Kim, David J.B, Marsh, Kennan C, O'Neill, Alyssa, Prendergast, Mark A, Ryther, Keith B, Sullivan, James P, Arneric, Stephen P

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Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles von Safina, Brian S, Elliott, Richard L, Forrest, Andrew K, Heald, Robert A, Murray, Jeremy M, Nonomiya, Jim, Pang, Jodie, Salphati, Laurent, Seward, Eileen M, Staben, Steven T, Ultsch, Mark, Wei, Binqing, Yang, Wenqian, Sutherlin, Daniel P

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Maximizing Lipophilic Efficiency: The Use of Free-Wilson Analysis in the Design of Inhibitors of Acetyl-CoA Carboxylase von Freeman-Cook, Kevin D, Amor, Paul, Bader, Scott, Buzon, Leanne M, Coffey, Steven B, Corbett, Jeffrey W, Dirico, Kenneth J, Doran, Shawn D, Elliott, Richard L, Esler, William, Guzman-Perez, Angel, Henegar, Kevin E, Houser, Janet A, Jones, Christopher S, Limberakis, Chris, Loomis, Katherine, McPherson, Kirk, Murdande, Sharad, Nelson, Kendra L, Phillion, Dennis, Pierce, Betsy S, Song, Wei, Sugarman, Eliot, Tapley, Susan, Tu, Meihua, Zhao, Zhengrong

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Piperidine-derived γ-secretase modulators von Hall, Adrian, Elliott, Richard L., Giblin, Gerard M.P., Hussain, Ishrut, Musgrave, James, Naylor, Alan, Sasse, Rosemary, Smith, Beverley

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The α-effect in cyclic secondary amines: new scaffolds for iminium ion accelerated transformations von Brazier, John B., Cavill, Julie L., Elliott, Richard L., Evans, Gareth, Gibbs, Timothy J.K., Jones, Ian L., Platts, James A., Tomkinson, Nicholas C.O.

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Depression in primary care von Elliott, Richard L

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Discovery of N-benzyl-2-[(4S)-4-(1H-indol-3-ylmethyl)-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl]-N-isopropylacetamide, an orally active, gut-selec... von Elliott, Richard L., Cameron, Kimberly O., Chin, Janice E., Bartlett, Jeremy A., Beretta, Elena E., Chen, Yue, Jardine, Paul Da Silva, Dubins, Jeffrey S., Gillaspy, Melissa L., Hargrove, Diane M., Kalgutkar, Amit S., LaFlamme, Janet A., Lame, Mary E., Martin, Kelly A., Maurer, Tristan S., Nardone, Nancy A., Oliver, Robert M., Scott, Dennis O., Sun, Dexue, Swick, Andrew G., Trebino, Catherine E., Zhang, Yingxin

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Quetiapine overdose and severe rhabdomyolysis von Smith, Richard P, Puckett, Ben N, Crawford, Jennifer, Elliott, Richard L

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Structure-activity relationship studies on 2-heteroaryl-4-arylimidazoles NPY5 receptor antagonists von ELLIOTT, Richard L, OLIVER, Robert M, MACK, Christine M, CASSELLA, James V, LAFLAMME, Janet A, GILLASPY, Melissa L, HAMMOND, Marlys, HANK, Richard F, MAURER, Tristan S, BAKER, Demetria L, DASILVA-JARDINE, Paul A, STEVENSON, Ralph W

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Pyridone derivatives as potent, orally bioavailable VLA-4 integrin antagonists von Witherington, Jason, Blaney, Emma L., Bordas, Vincent, Elliott, Richard L., Gaiba, Alessandra, Garton, Neil, Green, Philip M., Naylor, Antoinette, Smith, David G., Spalding, David J., Takle, Andrew K., Ward, Robert W.

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In Vitro and in Vivo Characterization of 3-{2-[6-(2-tert-Butoxyethoxy)pyridin-3-yl]-1H-imidazol-4-yl}benzonitrile Hydrochloride Salt, a Potent and Selective NPY5 Receptor Antagonis... von Elliott, Richard L, Oliver, Robert M, Hammond, Marlys, Patterson, Terrell A, She, Li, Hargrove, Diane M, Martin, Kelly A, Maurer, Tristan S, Kalvass, J. Cory, Morgan, Bradley P, DaSilva-Jardine, Paul A, Stevenson, Ralph W, Mack, Christine M, Cassella, James V

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The discovery of SB-435495: A potent, orally active inhibitor of lipoprotein-associated phospholipase A2 for evaluation in man von BLACKIE, Josie A, BLOOMER, Jackie C, MACPHEE, Colin H, MILLINER, Kevin J, MOORES, Kitty E, PINTO, Ivan L, SMITH, Stephen A, STANSFIELD, Ian G, STANWAY, Steven J, TAYLOR, Maxine A, THEOBALD, Colin J, WHITTAKER, Caroline M, BROWN, Murray J. B, CHENG, Hung-Yuan, ELLIOTT, Richard L, HAMMOND, Beverley, HICKEY, Deirdre M. B, IFE, Robert J, LEACH, Colin A, LEWIS, V. Ann

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Structure–activity relationships in a series of NPY Y5 antagonists: 3-amido-9-ethylcarbazoles, core-modified analogues and amide isosteres von Hammond, Marlys, Elliott, Richard L., Gillaspy, Melissa L., Hager, David C., Hank, Richard F., LaFlamme, Janet A., Oliver, Robert M., DaSilva-Jardine, Paul A., Stevenson, Ralph W., Mack, Christine M., Cassella, James V.

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A samarium(II) iodide promoted tandem radical cyclization. The total synthesis of (.+-.)-hypnophilin and the formal synthesis of (.+-.)-coriolin von Fevig, Thomas L, Elliott, Richard L, Curran, Dennis P

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Anhydrolide Macrolides. 1. Synthesis and Antibacterial Activity of 2,3-Anhydro-6-O-methyl 11,12-Carbamate Erythromycin A Analogues von Elliott, Richard L, Pireh, Daisy, Griesgraber, George, Nilius, Angela M, Ewing, Patty J, Bui, Mai Ha, Raney, Patti M, Flamm, Robert K, Kim, Ki, Henry, Rodger F, Chu, Daniel T. W, Plattner, Jacob J, Or, Yat Sun

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