Anti-obesity drug discovery: advances and challenges von Müller, Timo D., Blüher, Matthias, Tschöp, Matthias H., DiMarchi, Richard D.

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Peptide Conjugates with Small Molecules Designed to Enhance Efficacy and Safety von He, Rongjun, Finan, Brian, Mayer, John P, DiMarchi, Richard D

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Pursuit of a perfect insulin von Zaykov, Alexander N., Mayer, John P., DiMarchi, Richard D.

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Unimolecular Polypharmacy for Treatment of Diabetes and Obesity von Tschöp, Matthias H., Finan, Brian, Clemmensen, Christoffer, Gelfanov, Vasily, Perez-Tilve, Diego, Müller, Timo D., DiMarchi, Richard D.

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The Sustained Effects of a Dual GIP/GLP-1 Receptor Agonist, NNC0090-2746, in Patients with Type 2 Diabetes von Frias, Juan Pablo, Bastyr, Edward J., Vignati, Louis, Tschöp, Matthias H., Schmitt, Christophe, Owen, Klara, Christensen, Rune Haubo, DiMarchi, Richard D.

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A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents von Finan, Brian, Yang, Bin, Ottaway, Nickki, Smiley, David L, Ma, Tao, Clemmensen, Christoffer, Chabenne, Joe, Zhang, Lianshan, Habegger, Kirk M, Fischer, Katrin, Campbell, Jonathan E, Sandoval, Darleen, Seeley, Randy J, Bleicher, Konrad, Uhles, Sabine, Riboulet, William, Funk, Jürgen, Hertel, Cornelia, Belli, Sara, Sebokova, Elena, Conde-Knape, Karin, Konkar, Anish, Drucker, Daniel J, Gelfanov, Vasily, Pfluger, Paul T, Müller, Timo D, Perez-Tilve, Diego, DiMarchi, Richard D, Tschöp, Matthias H

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Reappraisal of GIP Pharmacology for Metabolic Diseases von Finan, Brian, Müller, Timo D, Clemmensen, Christoffer, Perez-Tilve, Diego, DiMarchi, Richard D, Tschöp, Matthias H

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Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism von Mroz, Piotr A., Finan, Brian, Gelfanov, Vasily, Yang, Bin, Tschöp, Matthias H., DiMarchi, Richard D., Perez-Tilve, Diego

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Recent Advances in Incretin-Based Pharmacotherapies for the Treatment of Obesity and Diabetes von Tan, Qiming, Akindehin, Seun E, Orsso, Camila E, Waldner, Richelle C, DiMarchi, Richard D, Müller, Timo D, Haqq, Andrea M

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Targeting the Incretin/Glucagon System With Triagonists to Treat Diabetes von Capozzi, Megan E, DiMarchi, Richard D, Tschöp, Matthias H, Finan, Brian, Campbell, Jonathan E

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GIPR/GLP-1R dual agonist therapies for diabetes and weight loss-chemistry, physiology, and clinical applications von Campbell, Jonathan E, Müller, Timo D, Finan, Brian, DiMarchi, Richard D, Tschöp, Matthias H, D'Alessio, David A

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The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling von Zhang, Qian, Delessa, Challa Tenagne, Augustin, Robert, Bakhti, Mostafa, Colldén, Gustav, Drucker, Daniel J., Feuchtinger, Annette, Caceres, Cristina Garcia, Grandl, Gerald, Harger, Alexandra, Herzig, Stephan, Hofmann, Susanna, Holleman, Cassie Lynn, Jastroch, Martin, Keipert, Susanne, Kleinert, Maximilian, Knerr, Patrick J., Kulaj, Konxhe, Legutko, Beata, Lickert, Heiko, Liu, Xue, Luippold, Gerd, Lutter, Dominik, Malogajski, Emilija, Medina, Marta Tarquis, Mowery, Stephanie A., Blutke, Andreas, Perez-Tilve, Diego, Salinno, Ciro, Sehrer, Laura, DiMarchi, Richard D., Tschöp, Matthias H., Stemmer, Kerstin, Finan, Brian, Wolfrum, Christian, Müller, Timo D.

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Icodec Advances the Prospect of Once-Weekly Insulin Injection von DiMarchi, Richard D, Mayer, John P

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Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases von Clemmensen, Christoffer, Finan, Brian, Müller, Timo D., DiMarchi, Richard D., Tschöp, Matthias H., Hofmann, Susanna M.

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Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis von Weiss, Andy, Murdoch, Caitlin C., Edmonds, Katherine A., Jordan, Matthew R., Monteith, Andrew J., Perera, Yasiru R., Rodríguez Nassif, Aslin M., Petoletti, Amber M., Beavers, William N., Munneke, Matthew J., Drury, Sydney L., Krystofiak, Evan S., Thalluri, Kishore, Wu, Hongwei, Kruse, Angela R.S., DiMarchi, Richard D., Caprioli, Richard M., Spraggins, Jeffrey M., Chazin, Walter J., Giedroc, David P., Skaar, Eric P.

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Smarter Modeling to Enable a Smarter Insulin von Taylor, Simeon I, DiMarchi, Richard D

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GLP-1/glucagon receptor co-agonism for treatment of obesity von Sánchez-Garrido, Miguel A., Brandt, Sara J., Clemmensen, Christoffer, Müller, Timo D., DiMarchi, Richard D., Tschöp, Matthias H.

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Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice von Knerr, Patrick J., Mowery, Stephanie A., Douros, Jonathan D., Premdjee, Bhavesh, Hjøllund, Karina Rahr, He, Yantao, Kruse Hansen, Ann Maria, Olsen, Anette K., Perez-Tilve, Diego, DiMarchi, Richard D., Finan, Brian

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Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions von HABEGGER, Kirk M, STEMMER, Kerstin, KRISHNA, Radha, ARAFAT, Ayman M, KONKAR, Anish, BELLI, Sara, KAPPS, Martin, WOODS, Stephen C, HOFMANN, Susanna M, D'ALESSIO, David, PFLUGER, Paul T, PEREZ-TILVE, Diego, CHENG, Christine, SEELEY, Randy J, KONISHI, Morichika, ITOH, Nobuyujki, KHARITONENKOV, Alexei, SPRANGER, Joachim, DIMARCHI, Richard D, TSCHÖP, Matthias H, MÜLLER, Timo D, HEPPNER, Kristy M, OTTAWAY, Nickki, HOLLAND, Jenna, HEMBREE, Jazzminn L, SMILEY, David, GELFANOV, Vasily

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Insights into incretin-based therapies for treatment of diabetic dyslipidemia von Stemmer, Kerstin, Finan, Brian, DiMarchi, Richard D., Tschöp, Matthias H., Müller, Timo D.

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