Silicone Oil- and Agitation-Induced Aggregation of a Monoclonal Antibody in Aqueous Solution von Thirumangalathu, Renuka, Krishnan, Sampathkumar, Ricci, Margaret Speed, Brems, David N., Randolph, Theodore W., Carpenter, John F.

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Elucidation of Degradants in Acidic Peak of Cation Exchange Chromatography in an IgG1 Monoclonal Antibody Formed on Long-Term Storage in a Liquid Formulation von Gandhi, Sejal, Ren, Da, Xiao, Gang, Bondarenko, Pavel, Sloey, Christopher, Ricci, Margaret Speed, Krishnan, Sampathkumar

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Optimization of a reversed-phase high-performance liquid chromatography/mass spectrometry method for characterizing recombinant antibody heterogeneity and stability von Dillon, Thomas M., Bondarenko, Pavel V., Rehder, Douglas S., Pipes, Gary D., Kleemann, Gerd R., Ricci, Margaret Speed

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Structural and Functional Characterization of Disulfide Isoforms of the Human IgG2 Subclass von Dillon, Thomas M., Ricci, Margaret Speed, Vezina, Chris, Flynn, Gregory C., Liu, Yaoqing Diana, Rehder, Douglas S., Plant, Matthew, Henkle, Brad, Li, Yu, Deechongkit, Songpon, Varnum, Brian, Wypych, Jette, Balland, Alain, Bondarenko, Pavel V.

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Human IgG2 Antibodies Display Disulfide-mediated Structural Isoforms von Wypych, Jette, Li, Ming, Guo, Amy, Zhang, Zhongqi, Martinez, Theresa, Allen, Martin J., Fodor, Szilan, Kelner, Drew N., Flynn, Gregory C., Liu, Yaoqing Diana, Bondarenko, Pavel V., Ricci, Margaret Speed, Dillon, Thomas M., Balland, Alain

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Development of an analytical reversed-phase high-performance liquid chromatography–electrospray ionization mass spectrometry method for characterization of recombinant antibodies von Dillon, Thomas M., Bondarenko, Pavel V., Speed Ricci, Margaret

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Effects of excipients on the hydrogen peroxide-induced oxidation of methionine residues in granulocyte colony-stimulating factor von Yin, Jin, Chu, Jhih-Wei, Ricci, Margaret Speed, Brems, David N, Wang, Daniel I C, Trout, Bernhardt L

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Effects of antioxidants on the hydrogen peroxide-mediated oxidation of methionine residues in granulocyte colony-stimulating factor and human parathyroid hormone fragment 13-34 von Yin, Jin, Chu, Jhih-Wei, Ricci, Margaret Speed, Brems, David N, Wang, Daniel I C, Trout, Bernhardt L

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Quantitative methods for developing Fc mutants with extended half-lives von Kamei, Daniel T., Lao, Bert J., Ricci, Margaret Speed, Deshpande, Rohini, Xu, Han, Tidor, Bruce, Lauffenburger, Douglas A.

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pH Dependence of structural stability of interleukin‐2 and granulocyte colony‐stimulating factor von Ricci, Margaret Speed, Sarkar, Casim A., Fallon, Eric M., Lauffenburger, Douglas A., Brems, David N.

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Rational design of lyophilized high concentration protein formulations-mitigating the challenge of slow reconstitution with multidisciplinary strategies von Cao, Wenjin, Krishnan, Sampathkumar, Ricci, Margaret Speed, Shih, Liang-Yu, Liu, Dingjiang, Gu, Jian Hua, Jameel, Feroz

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In-use physicochemical and microbiological stability of biological parenteral products von RICCI, MARGARET SPEED, FRAZIER, MICHELLE, MOORE, JAMIE, CROMWELL, MARY, GALUSH, WILLIAM J, PATEL, ANKIT R, ADLER, MICHAEL, ALTENBURGER, ULRIKE, GRAUSCHOPF, ULLA, GOLDBACH, PIERRE, FAST, JONAS L, KRÄMER, IRENE, MAHLER, HANNS-CHRISTIAN

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A Case Study of Nondelamination Glass Dissolution Resulting in Visible Particles: Implications for Neutral pH Formulations von Ratnaswamy, Gayathri, Hair, Alison, Li, Gary, Thirumangalathu, Renuka, Nashed-Samuel, Yasser, Brych, Lejla, Dharmavaram, Vasumathi, Wen, Zai-Qing, Fujimori, Kiyoshi, Jing, Wendy, Sethuraman, Ananth, Swift, Rob, Ricci, Margaret Speed, Piedmonte, Deirdre Murphy

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Oxidation of Methionine Residues in Recombinant Human Interleukin-1 Receptor Antagonist:  Implications of Conformational Stability on Protein Oxidation Kinetics von Thirumangalathu, Renuka, Krishnan, Sampathkumar, Bondarenko, Pavel, Speed-Ricci, Margaret, Randolph, Theodore W, Carpenter, John F, Brems, David N

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A comprehensive picture of non‐site specific oxidation of methionine residues by peroxides in protein pharmaceuticals von Chu, Jhih‐Wei, Yin, Jin, Brooks, Bernard R., Wang, Daniel I.C., Ricci, Margaret Speed, Brems, David N., Trout, Bernhardt L.

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Structural and Functional Characterization of Disulfide Isoforms of the Human IgG2 SubclassS von Dillon, Thomas M., Ricci, Margaret Speed, Vezina, Chris, Flynn, Gregory C., Liu, Yaoqing Diana, Rehder, Douglas S., Plant, Matthew, Henkle, Brad, Li, Yu, Deechongkit, Songpon, Varnum, Brian, Wypych, Jette, Balland, Alain, Bondarenko, Pavel V.

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Development of an analytical reversed-phase high-performance liquid chromatography-electrospray ionization mass spectrometry method for characterization of recombinant antibodies:... von DILLON, Thomas M, BONDARENKO, Pavel V, RICCI, Margaret Speed

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Development of an analytical reversed-phase high-performance liquid chromatography-electrospray ionization mass spectrometry method for characterization of recombinant antibodies von Dillon, Thomas M, Bondarenko, Pavel V, Speed Ricci, Margaret

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HOMOGENEOUS ANTIBODY POPULATIONS von Sun, Jeonghoon, Dillon, Thomas M, Vezina, Christopher John, Wypych, Jette, Ricci, Margaret Speed, Balland, Alain, Guo, Amy, Allen, Martin J, Bondarenko, Pavel, Shen, Wenyan

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METHODS OF PROCESSING A SAMPLE FOR PEPTIDE MAPPING ANALYSIS von XIAO, Gang, RICCI, Margaret Speed, CUI, Weidong, DYKSTRA, Andrew, RIGGS, Dylan, BONDARENKO, Pavel, DILLON, Thomas M, REN, Da, PAWLOWSKI, Jake, SHI, Liuqing, HARRAHY, John Joseph

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