Interleukin-36 (IL-36) Ligands Require Processing for Full Agonist (IL-36α, IL-36β, and IL-36γ) or Antagonist (IL-36Ra) Activity von Towne, Jennifer E., Renshaw, Blair R., Douangpanya, Jason, Lipsky, Brian P., Shen, Min, Gabel, Christopher A., Sims, John E.

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A novel mutation of IL1RN in the deficiency of interleukin‐1 receptor antagonist syndrome: Description of two unrelated cases from Brazil von Jesus, Adriana A., Osman, Mazen, Silva, Clovis A., Kim, Peter W., Pham, Tuyet‐Hang, Gadina, Massimo, Yang, Barbara, Bertola, Débora R., Carneiro‐Sampaio, Magda, Ferguson, Polly J., Renshaw, Blair R., Schooley, Ken, Brown, Michael, Al‐Dosari, Asma, Al‐Alami, Jamil, Sims, John E., Goldbach‐Mansky, Raphaela, El‐Shanti, Hatem

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Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis von Marrakchi, Slaheddine, Guigue, Philippe, Renshaw, Blair R, Puel, Anne, Pei, Xue-Yuan, Fraitag, Sylvie, Zribi, Jihen, Bal, Elodie, Cluzeau, Céline, Chrabieh, Maya, Towne, Jennifer E, Douangpanya, Jason, Pons, Christian, Mansour, Sourour, Serre, Valérie, Makni, Hafedh, Mahfoudh, Nadia, Fakhfakh, Faiza, Bodemer, Christine, Feingold, Josué, Hadj-Rabia, Smail, Favre, Michel, Genin, Emmanuelle, Sahbatou, Mourad, Munnich, Arnold, Casanova, Jean-Laurent, Sims, John E, Turki, Hamida, Bachelez, Hervé, Smahi, Asma

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Externalization of the Leaderless Cytokine IL-1F6 Occurs in Response to Lipopolysaccharide/ATP Activation of Transduced Bone Marrow Macrophages von Martin, Unja, Scholler, John, Gurgel, Jesse, Renshaw, Blair, Sims, John E, Gabel, Christopher A

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Genomic Organization of the Interleukin-1 Locus von Taylor, Scott L, Renshaw, Blair R, Garka, Kirsten E, Smith, Dirk E, Sims, John E

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Four New Members Expand the Interleukin-1 Superfamily von Smith, Dirk E., Renshaw, Blair R., Ketchem, Randal R., Kubin, Marek, Garka, Kirsten E., Sims, John E.

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IL-1Rrp2 expression and IL-1F9 (IL-1H1) actions in brain cells von Berglöf, Elisabet, Andre, Ralph, Renshaw, Blair R., Allan, Stuart M., Lawrence, Catherine B., Rothwell, Nancy J., Pinteaux, Emmanuel

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Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death von Ware, C B, Horowitz, M C, Renshaw, B R, Hunt, J S, Liggitt, D, Koblar, S A, Gliniak, B C, McKenna, H J, Papayannopoulou, T, Thoma, B

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Abstract 6309: Anti-tumor efficacy of SI-B001, a novel EGFR × HER3 bispecific antibody, against EGFR-driven epithelial tumors alone or in combination with paclitaxel and carboplati... von Renshaw, Blair, Khalili, Jahan Salar, Xiao, Sa, Zhu, Yi

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Interleukin (IL)-1F6, IL-1F8, and IL-1F9 Signal through IL-1Rrp2 and IL-1RAcP to Activate the Pathway Leading to NF-κB and MAPKs von Towne, Jennifer E., Garka, Kirsten E., Renshaw, Blair R., Virca, G. Duke, Sims, John E.

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Abstract 2642: BL-B01D1, a novel EGFR×HER3-targeting ADC, demonstrates robust anti-tumor efficacy in preclinical evaluation von Wan, Weili, Zhao, Shuwen, Zhuo, Shi, Zhang, Yong, Chen, Lan, Li, Gangrui, Renshaw, Blair, Khalili, Jahan Salar, Xiao, Sa, Zhu, Yi

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Binding of interleukin-18 to the interleukin-1 receptor homologous receptor IL-1Rrp1 leads to activation of signaling pathways similar to those used by interleukin-1 von Thomassen, E, Bird, T A, Renshaw, B R, Kennedy, M K, Sims, J E

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Externalization of the leaderless cytokine IL-1F6 occurs in response to LPS/ATP activation of transduced bone marrow derived macrophages (38.10) von Martin, Unja, Gurgel, Jesse, Scholler, John, Renshaw, Blair, Gabel, Chris

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IDENTIFICATION AND CHARACTERIZATION OF SIGIRR, A MOLECULE REPRESENTING A NOVEL SUBTYPE OF THE IL-1R SUPERFAMILY von Thomassen, Elisabeth, Renshaw, Blair R., Sims, John E.

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Cloning of a Putative Ligand for the T1/ST2 Receptor (∗) von Gayle, Margit A., Slack, Jennifer L., Bonnert, Timothy P., Renshaw, Blair R., Sonoda, Gonosuke, Taguchi, Takahiro, Testa, Joseph R., Dower, Steven K., Sims, John E.

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Humoral immune responses in CD40 ligand-deficient mice von Renshaw, B R, Fanslow, 3rd, W C, Armitage, R J, Campbell, K A, Liggitt, D, Wright, B, Davison, B L, Maliszewski, C R

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Identification and characterization of two members of a novel class of the interleukin-1 receptor (IL-1R) family. Delineation of a new class of IL-1R-related proteins based on sign... von Born, T L, Smith, D E, Garka, K E, Renshaw, B R, Bertles, J S, Sims, J E

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PS1-43 IL-1F ligands require processing for full agonist (IL-1f6, IL-1f8 and IL-1f9) or antagonist (IL-1f5) activity von Towne, Jennifer E, Renshaw, Blair R, Douangpanya, Jason, Lipsky, Brian P, Shen, Min, Gabel, Christopher A, Sims, John E

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The interleukin-1-related cytokine IL-1F8 is expressed in glial cells, but fails to induce IL-1β signalling responses von Wang, Penglian, Meinhardt, Brenda, Andre, Ralph, Renshaw, Blair R., Kimber, Ian, Rothwell, Nancy J., Pinteaux, Emmanuel

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Identification and Characterization of Two Members of a Novel Class of the Interleukin-1 Receptor (IL-1R) Family von Born, Teresa L., Smith, Dirk E., Garka, Kirsten E., Renshaw, Blair R., Bertles, Jeanette S., Sims, John E.

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