Therapeutic Inhibition of Myc in Cancer. Structural Bases and Computer-Aided Drug Discovery Approaches von Carabet, Lavinia A, Rennie, Paul S, Cherkasov, Artem

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Best Practices of Computer-Aided Drug Discovery: Lessons Learned from the Development of a Preclinical Candidate for Prostate Cancer with a New Mechanism of Action von Ban, Fuqiang, Dalal, Kush, Li, Huifang, LeBlanc, Eric, Rennie, Paul S, Cherkasov, Artem

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IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling von Sheng, Xia, Nenseth, Hatice Zeynep, Qu, Su, Kuzu, Omer F., Frahnow, Turid, Simon, Lukas, Greene, Stephanie, Zeng, Qingping, Fazli, Ladan, Rennie, Paul S., Mills, Ian G., Danielsen, Håvard, Theis, Fabian, Patterson, John B., Jin, Yang, Saatcioglu, Fahri

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Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer von Lallous, Nada, Dalal, Kush, Cherkasov, Artem, Rennie, Paul S

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Toxic Colors: The Use of Deep Learning for Predicting Toxicity of Compounds Merely from Their Graphic Images von Fernandez, Michael, Ban, Fuqiang, Woo, Godwin, Hsing, Michael, Yamazaki, Takeshi, LeBlanc, Eric, Rennie, Paul S, Welch, William J, Cherkasov, Artem

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Computer-Aided Ligand Discovery for Estrogen Receptor Alpha von Bafna, Divya, Ban, Fuqiang, Rennie, Paul S, Singh, Kriti, Cherkasov, Artem

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ETS transcription factors as emerging drug targets in cancer von Hsing, Michael, Wang, Yuzhuo, Rennie, Paul S., Cox, Michael E., Cherkasov, Artem

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Discovery of Small-Molecule Inhibitors Selectively Targeting the DNA-Binding Domain of the Human Androgen Receptor von Li, Huifang, Ban, Fuqiang, Dalal, Kush, Leblanc, Eric, Frewin, Kate, Ma, Dennis, Adomat, Hans, Rennie, Paul S, Cherkasov, Artem

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Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling von Bluemn, Eric G., Coleman, Ilsa M., Lucas, Jared M., Coleman, Roger T., Hernandez-Lopez, Susana, Tharakan, Robin, Bianchi-Frias, Daniella, Dumpit, Ruth F., Kaipainen, Arja, Corella, Alexandra N., Yang, Yu Chi, Nyquist, Michael D., Mostaghel, Elahe, Hsieh, Andrew C., Zhang, Xiaotun, Corey, Eva, Brown, Lisha G., Nguyen, Holly M., Pienta, Kenneth, Ittmann, Michael, Schweizer, Michael, True, Lawrence D., Wise, David, Rennie, Paul S., Vessella, Robert L., Morrissey, Colm, Nelson, Peter S.

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Computer-Aided Discovery of Small Molecules Targeting the RNA Splicing Activity of hnRNP A1 in Castration-Resistant Prostate Cancer von Carabet, Lavinia A, Leblanc, Eric, Lallous, Nada, Morin, Helene, Ghaidi, Fariba, Lee, Joseph, Rennie, Paul S, Cherkasov, Artem

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Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression von Zhang, Fan, Biswas, Maitree, Massah, Shabnam, Lee, Joseph, Lingadahalli, Shreyas, Wong, Samantha, Wells, Christopher, Foo, Jane, Khan, Nabeel, Morin, Helene, Saxena, Neetu, Kung, Sonia H Y, Sun, Bei, Parra Nuñez, Ana Karla, Sanchez, Christophe, Chan, Novia, Ung, Lauren, Altıntaş, Umut Berkay, Bui, Jennifer M, Wang, Yuzhuo, Fazli, Ladan, Oo, Htoo Zarni, Rennie, Paul S, Lack, Nathan A, Cherkasov, Artem, Gleave, Martin E, Gsponer, Jörg, Lallous, Nada

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Oncolytic Virotherapy Blockade by Microglia and Macrophages Requires STAT1/3 von Delwar, Zahid M, Kuo, Yvonne, Wen, Yan H, Rennie, Paul S, Jia, William

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The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis von Massie, Charles E, Lynch, Andy, Ramos-Montoya, Antonio, Boren, Joan, Stark, Rory, Fazli, Ladan, Warren, Anne, Scott, Helen, Madhu, Basetti, Sharma, Naomi, Bon, Helene, Zecchini, Vinny, Smith, Donna-Michelle, DeNicola, Gina M, Mathews, Nik, Osborne, Michelle, Hadfield, James, MacArthur, Stewart, Adryan, Boris, Lyons, Scott K, Brindle, Kevin M, Griffiths, John, Gleave, Martin E, Rennie, Paul S, Neal, David E, Mills, Ian G

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Functional analysis of androgen receptor mutations that confer anti-androgen resistance identified in circulating cell-free DNA from prostate cancer patients von Lallous, Nada, Volik, Stanislav V, Awrey, Shannon, Leblanc, Eric, Tse, Ronnie, Murillo, Josef, Singh, Kriti, Azad, Arun A, Wyatt, Alexander W, LeBihan, Stephane, Chi, Kim N, Gleave, Martin E, Rennie, Paul S, Collins, Colin C, Cherkasov, Artem

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Androgen-regulated processing of the oncomir MiR-27a, which targets Prohibitin in prostate cancer von FLETCHER, Claire E, DART, D. Alwyn, SITA-LUMSDEN, Ailsa, CHENG, Helen, RENNIE, Paul S, BEAN, Charlotte L

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Computer-Aided Discovery of Small Molecule Inhibitors of Transcriptional Activity of TLX (NR2E1) Nuclear Receptor von Dueva, Evgenia, Singh, Kriti, Kalyta, Anastasia, LeBlanc, Eric, Rennie, Paul S, Cherkasov, Artem

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Development of Novel Inhibitors Targeting the D-Box of the DNA Binding Domain of Androgen Receptor von Radaeva, Mariia, Ban, Fuqiang, Zhang, Fan, LeBlanc, Eric, Lallous, Nada, Rennie, Paul S, Gleave, Martin E, Cherkasov, Artem

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Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor through Virtual Screening von Lack, Nathan A, Axerio-Cilies, Peter, Tavassoli, Peyman, Han, Frank Q, Chan, Ka Hong, Feau, Clementine, LeBlanc, Eric, Guns, Emma Tomlinson, Guy, R. Kiplin, Rennie, Paul S, Cherkasov, Artem

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Selectively Targeting the DNA-binding Domain of the Androgen Receptor as a Prospective Therapy for Prostate Cancer von Dalal, Kush, Roshan-Moniri, Mani, Sharma, Aishwariya, Li, Huifang, Ban, Fuqiang, Hessein, Mohamed, Hsing, Michael, Singh, Kriti, LeBlanc, Eric, Dehm, Scott, Tomlinson Guns, Emma S., Cherkasov, Artem, Rennie, Paul S.

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Author Correction: IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling von Sheng, Xia, Nenseth, Hatice Zeynep, Qu, Su, Kuzu, Omer F., Frahnow, Turid, Simon, Lukas, Greene, Stephanie, Zeng, Qingping, Fazli, Ladan, Rennie, Paul S., Mills, Ian G., Danielsen, Håvard, Theis, Fabian, Patterson, John B., Jin, Yang, Saatcioglu, Fahri

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