ABT-414, an Antibody-Drug Conjugate Targeting a Tumor-Selective EGFR Epitope von Phillips, Andrew C, Boghaert, Erwin R, Vaidya, Kedar S, Mitten, Michael J, Norvell, Suzanne, Falls, Hugh D, DeVries, Peter J, Cheng, Dong, Meulbroek, Jonathan A, Buchanan, Fritz G, McKay, Laura M, Goodwin, Neal C, Reilly, Edward B

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ABBV-176, a PRLR antibody drug conjugate with a potent DNA-damaging PBD cytotoxin and enhanced activity with PARP inhibition von Anderson, Mark G, Zhang, Qian, Rodriguez, Luis E, Hecquet, Claudie M, Donawho, Cherrie K, Ansell, Peter J, Reilly, Edward B

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Biodistribution Analysis of an Anti-EGFR Antibody in the Rat Brain: Validation of CSF Microcirculation as a Viable Pathway to Circumvent the Blood-Brain Barrier for Drug Delivery von Naseri Kouzehgarani, Ghazal, Kumar, Pankaj, Bolin, Susan E., Reilly, Edward B., Lefebvre, Didier R.

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Characterization of ABBV-221, a Tumor-Selective EGFR-Targeting Antibody Drug Conjugate von Phillips, Andrew C, Boghaert, Erwin R, Vaidya, Kedar S, Falls, Hugh D, Mitten, Michael J, DeVries, Peter J, Benatuil, Lorenzo, Hsieh, Chung-Ming, Meulbroek, Jonathan A, Panchal, Sanjay C, Buchanan, Fritz G, Durbin, Kenneth R, Voorbach, Martin J, Reuter, David R, Mudd, Sarah R, Loberg, Lise I, Ralston, Sherry L, Cao, Diana, Gan, Hui K, Scott, Andrew M, Reilly, Edward B

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Novel p-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 2. Mechanism of Inhibition and Structure-Based... von Liu, Gang, Huth, Jeffrey R, Olejniczak, Edward T, Mendoza, Renaldo, DeVries, Peter, Leitza, Sandra, Reilly, Edward B, Okasinski, Gregory F, Fesik, Stephen W, von Geldern, Thomas W

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Targeting and Efficacy of Novel mAb806-Antibody-Drug Conjugates in Malignant Mesothelioma von Chia, Puey-Ling, Parakh, Sagun, Tsao, Ming-Sound, Pham, Nhu-An, Gan, Hui K, Cao, Diana, Burvenich, Ingrid J G, Rigopoulos, Angela, Reilly, Edward B, John, Thomas, Scott, Andrew M

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First-in-Human Phase I, Dose-Escalation and -Expansion Study of Telisotuzumab Vedotin, an Antibody-Drug Conjugate Targeting c-Met, in Patients With Advanced Solid Tumors von Strickler, John H, Weekes, Colin D, Nemunaitis, John, Ramanathan, Ramesh K, Heist, Rebecca S, Morgensztern, Daniel, Angevin, Eric, Bauer, Todd M, Yue, Huibin, Motwani, Monica, Parikh, Apurvasena, Reilly, Edward B, Afar, Daniel, Naumovski, Louie, Kelly, Karen

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ABBV-399, a c-Met Antibody-Drug Conjugate that Targets Both MET -Amplified and c-Met-Overexpressing Tumors, Irrespective of MET Pathway Dependence von Wang, Jieyi, Anderson, Mark G, Oleksijew, Anatol, Vaidya, Kedar S, Boghaert, Erwin R, Tucker, Lora, Zhang, Qian, Han, Edward K, Palma, Joann P, Naumovski, Louie, Reilly, Edward B

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Discovery of Novel p-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 1. Identification of an Additional... von Liu, Gang, Link, J. T, Pei, Zhonghua, Reilly, Edward B, Leitza, Sandra, Nguyen, Bach, Marsh, Kennan C, Okasinski, Gregory F, von Geldern, Thomas W, Ormes, Mark, Fowler, Kerry, Gallatin, Mike

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Targeting Multiple EGFR-expressing Tumors with a Highly Potent Tumor-selective Antibody–Drug Conjugate von Anderson, Mark G., Falls, Hugh D., Mitten, Michael J., Oleksijew, Anatol, Vaidya, Kedar S., Boghaert, Erwin R., Gao, Wenqing, Palma, Joann P., Cao, Diana, Chia, Puey-Ling, John, Thomas, Gan, Hui K., Scott, Andrew M., Reilly, Edward B.

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A Phase 1 and Biodistribution Study of ABT-806i, an 111In-Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806 von Gan, Hui K, Burge, Matthew, Solomon, Benjamin, Lee, Sze Ting, Holen, Kyle D, Zhang, Yumin, Ciprotti, Marika, Lee, FT, Munasinghe, Wijith, Fischer, JuDee, Ansell, Peter, Fox, Gerard, Xiong, Hao, Reilly, Edward B, Humerickhouse, Rod, Scott, Andrew M

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ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies von Chervin, Adam S, Stone, Jennifer D, Konieczna, Iwona, Calabrese, Kelly M, Wang, Ningyan, Haribhai, Dipica, Dong, Feng, White, Michael K, Rodriguez, Luis E, Bukofzer, Gail T, Ellis, Paul A, Cosgrove, Cormac, Hecquet, Claudie, Clarin, Jerry D, Palma, Joann P, Reilly, Edward B

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Efficacy and safety results of depatuxizumab mafodotin (ABT‐414) in patients with advanced solid tumors likely to overexpress epidermal growth factor receptor von Goss, Glenwood D., Vokes, Everett E., Gordon, Michael S., Gandhi, Leena, Papadopoulos, Kyriakos P., Rasco, Drew W., Fischer, JuDee S., Chu, Katharine L., Ames, William W., Mittapalli, Rajendar K., Lee, Ho‐Jin, Zeng, Jiewei, Roberts‐Rapp, Lisa A., Loberg, Lise I., Ansell, Peter J., Reilly, Edward B., Ocampo, Christopher J., Holen, Kyle D., Tolcher, Anthony W.

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Characterization of ABT-806, a Humanized Tumor-Specific Anti-EGFR Monoclonal Antibody von Reilly, Edward B, Phillips, Andrew C, Buchanan, Fritz G, Kingsbury, Gillian, Zhang, Yumin, Meulbroek, Jonathan A, Cole, Todd B, DeVries, Peter J, Falls, Hugh D, Beam, Christine, Gu, Jinming, Digiammarino, Enrico L, Palma, Joann P, Donawho, Cherrie K, Goodwin, Neal C, Scott, Andrew M

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Synergistic therapeutic benefit by combining the antibody drug conjugate, depatux-m with temozolomide in pre-clinical models of glioblastoma with overexpression of EGFR von Vaidya, Kedar S., Mitten, Michael J., Zelaya-Lazo, Adelyn L., Oleksijew, Anatol, Alvey, Cory, Falls, Hugh D., Mishra, Sasmita, Palma, Joann, Ansell, Peter, Phillips, Andrew C., Reilly, Edward B., Anderson, Mark, Boghaert, Erwin R.

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A potent erythropoietin-mimicking human antibody interacts through a novel binding site von Liu, Zhihong, Stoll, Vincent S., DeVries, Peter J., Jakob, Clarissa G., Xie, Nancy, Simmer, Robert L., Lacy, Susan E., Egan, David A., Harlan, John E., Lesniewski, Richard R., Reilly, Edward B.

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Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification von Wang, Jieyi, Goetsch, Liliane, Tucker, Lora, Zhang, Qian, Gonzalez, Alexandra, Vaidya, Kedar S, Oleksijew, Anatol, Boghaert, Erwin, Song, Minghao, Sokolova, Irina, Pestova, Ekaterina, Anderson, Mark, Pappano, William N, Ansell, Peter, Bhathena, Anahita, Naumovski, Louie, Corvaia, Nathalie, Reilly, Edward B

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Cytotoxicity of the CD3×CD20 bispecific antibody epcoritamab in CLL is increased by concurrent BTK or BCL-2 targeting von Mhibik, Maissa, Gaglione, Erika M., Eik, David, Herrick, John, Le, Janet, Ahn, Inhye E., Chiu, Christopher, Wielgos-Bonvallet, Monica, Hiemstra, Ida H., Breij, Esther C. W., Chen, Jenny, Reilly, Edward B., Epling-Burnette, Pearlie K., Szafer-Glusman, Edith, Sun, Clare, Wiestner, Adrian

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A phase 1 study of ABT-806 in subjects with advanced solid tumors von Cleary, James M., Reardon, David A., Azad, Nilofer, Gandhi, Leena, Shapiro, Geoffrey I., Chaves, Jorge, Pedersen, Michelle, Ansell, Peter, Ames, William, Xiong, Hao, Munasinghe, Wijith, Dudley, Matt, Reilly, Edward B., Holen, Kyle, Humerickhouse, Rod

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Phase I study of anti-epidermal growth factor receptor antibody-drug conjugate serclutamab talirine: Safety, pharmacokinetics, and antitumor activity in advanced glioblastoma von Carneiro, Benedito A, Papadopoulos, Kyriakos P, Strickler, John H, Lassman, Andrew B, Waqar, Saiama N, Chae, Young Kwang, Patel, Jyoti D, Shacham-Shmueli, Einat, Kelly, Karen, Khasraw, Mustafa, Bestvina, Christine M, Merrell, Ryan, Huang, Kevin, Atluri, Harisha, Ansell, Peter, Li, Rachel, Jin, Janet, Anderson, Mark G, Reilly, Edward B, Morrison-Thiele, Gladys, Patel, Kalpesh, Robinson, Randy R, Aristide, Martha R Neagu, Gan, Hui K

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