CNS delivery of targeted protein degraders von Agarwal, Prashant, Reid, Darren L., Amiji, Mansoor

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Trends in small molecule drug properties: A developability molecule assessment perspective von Agarwal, Prashant, Huckle, James, Newman, Jake, Reid, Darren L.

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In Silico Prediction of Pharmaceutical Degradation Pathways: A Benchmarking Study von Kleinman, Mark H, Baertschi, Steven W, Alsante, Karen M, Reid, Darren L, Mowery, Mark D, Shimanovich, Roman, Foti, Chris, Smith, William K, Reynolds, Dan W, Nefliu, Marcela, Ott, Martin A

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Clearance prediction for Amgen molecules against Extended Clearance Classification System (ECCS) and future directions von Agarwal, Prashant, Ishida, Kazuya, Reid, Darren L., Gupta, Anshul

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Structural characterization and developability assessment of sustained release hydrogels for rapid implementation during preclinical studies von Agarwal, Prashant, Greene, Daniel G., Sherman, Scott, Wendl, Kaitlyn, Vega, Leonela, Park, Hyunsoo, Shimanovich, Roman, Reid, Darren L.

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Emerging Process Modeling Capabilities for Dry Powder Operations for Inhaled Formulations von Lou, Hao, Ding, Li, Wu, Tian, Li, Weikun, Khalaf, Ryan, Smyth, Hugh D. C., Reid, Darren L.

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Entropies in Solution from Entropies in the Gas Phase von Leung, Bonnie O, Reid, Darren L, Armstrong, David A, Rauk, Arvi

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The Evolving Druggability and Developability Space: Chemically Modified New Modalities and Emerging Small Molecules von Yang, Wenzhan, Gadgil, Prajakta, Krishnamurthy, Venkata R., Landis, Margaret, Mallick, Pankajini, Patel, Dipal, Patel, Phenil J., Reid, Darren L., Sanchez-Felix, Manuel

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Modulating target engagement of small molecules via drug delivery: approaches and applications in drug discovery and development von Yang, Wenzhan, Bhattachar, Shobha N., Patel, Phenil J., Landis, Margaret, Patel, Dipal, Reid, Darren L., Duvnjak Romic, Marieta

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Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors von Wurz, Ryan P., Sastri, Christine, D’Amico, Derin C., Herberich, Brad, Jackson, Claire L.M., Pettus, Liping H., Tasker, Andrew S., Wu, Bin, Guerrero, Nadia, Lipford, J. Russell, Winston, Jeffrey T., Yang, Yajing, Wang, Paul, Nguyen, Yen, Andrews, Kristin L., Huang, Xin, Lee, Matthew R., Mohr, Christopher, Zhang, J.D., Reid, Darren L., Xu, Yang, Zhou, Yihong, Wang, Hui-Ling

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A Quantitative Kinetic Study of Polysorbate Autoxidation: The Role of Unsaturated Fatty Acid Ester Substituents von Yao, Jia, Dokuru, Dushyanth K., Noestheden, Matthew, Park, SungAe S., Kerwin, Bruce A., Jona, Janan, Ostovic, Drazen, Reid, Darren L.

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The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors von Wurz, Ryan P., Pettus, Liping H., Jackson, Claire, Wu, Bin, Wang, Hui-Ling, Herberich, Brad, Cee, Victor, Lanman, Brian A., Reed, Anthony B., Chavez, Frank, Nixey, Thomas, Laszlo, Jimmy, Wang, Paul, Nguyen, Yen, Sastri, Christine, Guerrero, Nadia, Winston, Jeff, Lipford, J. Russell, Lee, Matthew R., Andrews, Kristin L., Mohr, Christopher, Xu, Yang, Zhou, Yihong, Reid, Darren L., Tasker, Andrew S.

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Novel Cytochrome P450 Bioactivation of a Terminal Phenyl Acetylene Group: Formation of a One-Carbon Loss Benzaldehyde and Other Oxidative Products in the Presence of N-Acetyl Cyste... von Subramanian, Raju, Tam, Janet, Aidasani, Divesh, Reid, Darren L, Skiles, Gary L

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H-atom abstraction from thiols by C-centered radicals. A theoretical and experimental study of reaction rates von Reid, Darren L., Shustov, Gennady V., Armstrong, David A., Rauk, Arvi, Schuchmann, Man Nien, Akhlaq, M. Shahid, von Sonntag, Clemens

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pH control of nucleophilic/electrophilic oxidation von Freed, Anita L., Strohmeyer, Holly E., Mahjour, Majid, Sadineni, Vikram, Reid, Darren L., Kingsmill, Carol A.

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Discovery of 2-methylpyridine-based biaryl amides as γ-secretase modulators for the treatment of Alzheimer’s disease von Chen, Jian Jeffrey, Qian, Wenyuan, Biswas, Kaustav, Yuan, Chester, Amegadzie, Albert, Liu, Qingyian, Nixey, Thomas, Zhu, Joe, Ncube, Mqhele, Rzasa, Robert M., Chavez, Frank, Chen, Ning, DeMorin, Frenel, Rumfelt, Shannon, Tegley, Christopher M., Allen, Jennifer R., Hitchcock, Stephen, Hungate, Randy, Bartberger, Michael D., Zalameda, Leeanne, Liu, Yichin, McCarter, John D., Zhang, Jianhua, Zhu, Li, Babu-Khan, Safura, Luo, Yi, Bradley, Jodi, Wen, Paul H., Reid, Darren L., Koegler, Frank, Dean, Charles, Hickman, Dean, Correll, Tiffany L., Williamson, Toni, Wood, Stephen

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Oxopyrido[2,3‑d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors von Wurz, Ryan P, Pettus, Liping H, Ashton, Kate, Brown, James, Chen, Jian Jeffrey, Herberich, Brad, Hong, Fang-Tsao, Hu-Harrington, Essa, Nguyen, Tom, St. Jean, David J, Tadesse, Seifu, Bauer, David, Kubryk, Michele, Zhan, Jinghui, Cooke, Keegan, Mitchell, Petia, Andrews, Kristin L, Hsieh, Faye, Hickman, Dean, Kalyanaraman, Nataraj, Wu, Tian, Reid, Darren L, Lobenhofer, Edward K, Andrews, Dina A, Everds, Nancy, Guzman, Roberto, Parsons, Andrew T, Hedley, Simon J, Tedrow, Jason, Thiel, Oliver R, Potter, Matthew, Radinsky, Robert, Beltran, Pedro J, Tasker, Andrew S

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H-atom abstraction by thiyl radicals from peptides and cyclic dipeptides. A theoretical study of reaction rates von REID, Darren L, ARMSTRONG, David A, RAUK, Arvi, VON SONNTAG, Clemens

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Early prediction of pharmaceutical oxidation pathways by computational chemistry and forced degradation von Reid, Darren L, Calvitt, C Jeffrey, Zell, Mark T, Miller, Kenneth G, Kingsmill, Carol A

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In Silico Prediction of Pharmaceutical Degradation Pathways: A Benchmarking Study Using the Software Program Zeneth von Hemingway, Rachel, Baertschi, Steven W., Benstead, David, Campbell, John M., Coombs, Maggie, Huang, Zongyun, Khalaf, Ryan, Ott, Martin A., Ponting, David J., Reid, Darren L., Stevenson, Neil G., Webb, Samuel J., White, Angela, Zelesky, Todd

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