A genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicity von Pettitt, Stephen J, Rehman, Farah L, Bajrami, Ilirjana, Brough, Rachel, Wallberg, Fredrik, Kozarewa, Iwanka, Fenwick, Kerry, Assiotis, Ioannis, Chen, Lina, Campbell, James, Lord, Christopher J, Ashworth, Alan

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Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity von BAJRAMI, Ilirjana, FRANKUM, Jessica R, CHEN, Lina, KOZAREWA, Iwanka, ASSIOTIS, Ioannis, FENWICK, Kerry, NATRAJAN, Rachael, LORD, Christopher J, ASHWORTH, Alan, KONDE, Asha, MILLER, Rowan E, REHMAN, Farah L, BROUGH, Rachel, CAMPBELL, James, SIMS, David, RAFIQ, Rumana, HOOPER, Sean

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Personalized Detection of Circulating Tumor DNA Antedates Breast Cancer Metastatic Recurrence von Coombes, Raoul Charles, Page, Karen, Salari, Raheleh, Hastings, Robert K, Armstrong, Anne, Ahmed, Samreen, Ali, Simak, Cleator, Susan, Kenny, Laura, Stebbing, Justin, Rutherford, Mark, Sethi, Himanshu, Boydell, Anna, Swenerton, Ryan, Fernandez-Garcia, Daniel, Gleason, Kelly L T, Goddard, Katie, Guttery, David S, Assaf, Zoe J, Wu, Hsin-Ta, Natarajan, Prashanthi, Moore, David A, Primrose, Lindsay, Dashner, Scott, Tin, Antony S, Balcioglu, Mustafa, Srinivasan, Ramya, Shchegrova, Svetlana V, Olson, Alexander, Hafez, Dina, Billings, Paul, Aleshin, Alexey, Rehman, Farah, Toghill, Bradley J, Hills, Allison, Louie, Maggie C, Lin, Cheng-Ho Jimmy, Zimmermann, Bernhard G, Shaw, Jaqueline A

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The promise of combining inhibition of PI3K and PARP as cancer therapy von Rehman, Farah L, Lord, Christopher J, Ashworth, Alan

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Comparison of two targeted ultra-deep sequencing technologies for analysis of plasma circulating tumour DNA in endocrine-therapy-resistant breast cancer patients von Nteliopoulos, Georgios, Page, Karen, Hills, Allison, Howarth, Karen, Emmett, Warren, Green, Emma, Martinson, Luke J., Fernadez-Garcia, Daniel, Hastings, Robert, Guttery, David S., Kenny, Laura, Stebbing, Justin, Cleator, Susan, Rehman, Farah, Gleason, Kelly L. T., Sanela, Andrijac, Ion, Charlotte, Rushton, Amelia J., Rosenfeld, Nitzan, Coombes, R. Charles, Shaw, Jacqueline A.

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Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells von Pettitt, Stephen J., Krastev, Dragomir B., Pemberton, Helen N., Fontebasso, Yari, Frankum, Jessica, Rehman, Farah L., Brough, Rachel, Song, Feifei, Bajrami, Ilirjana, Rafiq, Rumana, Wallberg, Fredrik, Kozarewa, Iwanka, Fenwick, Kerry, Armisen-Garrido, Javier, Swain, Amanda, Gulati, Aditi, Campbell, James, Ashworth, Alan, Lord, Christopher J.

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BMN 673, a Novel and Highly Potent PARP1/2 Inhibitor for the Treatment of Human Cancers with DNA Repair Deficiency von YUQIAO SHEN, REHMAN, Farah L, YING FENG, BOSHUIZEN, Julia, BAJRAMI, Ilirjana, ELLIOTT, Richard, BING WANG, LORD, Christopher J, POST, Leonard E, ASHWORTH, Alan

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Sequence based analysis of U-2973, a cell line established from a double-hit B-cell lymphoma with concurrent MYC and BCL2 rearrangements von Hooper, Sean D, Jiao, Xiang, Sundström, Elisabeth, Rehman, Farah L, Tellgren-Roth, Christian, Sjöblom, Tobias, Cavelier, Lucia

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Immobilization of acrylamide-modified oligonucleotides by co-polymerization von Rehman, Farah N., Audeh, Mark, Abrams, Ezra S., Hammond, Philip W., Kenney, Mary, Boles, T. Christian

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ASA404: update on drug development von Rehman, Farah, Rustin, Gordon

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Contraceptive Practices and the Reasons for Non-Utilization of Contraceptives among Married Women in an Urban Slum von Butt, Zarabia Pervaiz, Usmani, Rabia Arshed, Kashmiri, Misbah Jehangir, Hasnain, Seema, Khalil, Kashif Ur Rehman, Rehman, Farah

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Serial postoperative ctDNA monitoring of breast cancer recurrence von Shaw, Jacqueline, Page, Karen, Ambasger, Bana, De Bruin, Elza, Kalashnikova, Ekaterina, Hastings, Rob, McEwen, Robert, Allsopp, Rebecca Amanda, Sethi, Himanshu, Gleason, Kelly L.T., Stetson, Daniel, Fernandez Garci, Daniel, Guttery, David, Rehman, Farah, Renner, Derrick, Ali, Simak, Ahmed, Samreen, Armstrong, Anne C., Coombes, R. Charles

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Development of the HT&Me intervention to support women with breast cancer to adhere to adjuvant endocrine therapy and improve quality of life von Stewart, Sarah-Jane F., Slodkowska-Barabasz, Joanna, McGeagh, Lucy, Moon, Zoe, Brett, Jo, Wells, Mary, Brown, Morven C., Turner, Mark, Horne, Robert, Fenlon, Deborah, Rehman, Farah, Cain, Henry, Donnelly, Peter, Harmer, Victoria, Turner, Lesley, Rose, Jan, Sharp, Linda, Watson, Eila

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Palbociclib and endocrine therapy in heavily pretreated hormone receptor-positive HER2-negative advanced breast cancer: the UK Compassionate Access Programme experience von Battisti, Nicolò Matteo Luca, Kingston, Belinda, King, Judy, Denton, Arshi, Waters, Simon, Sita-Lumsden, Ailsa, Rehman, Farah, Stavraka, Chara, Kristeleit, Hartmut, Sawyer, Elinor, Houghton, David, Davidson, Neville, Howell, Sacha, Choy, Julia, Harper, Peter, Roylance, Rebecca, Fharat, Raja, Mohammed, Kabir, Ring, Alistair, Johnston, Stephen

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Abstract P1-17-08: Abemaciclib and endocrine therapy for hormone receptor-positive, HER2-negative advanced breast cancer: A real-world UK multicentre experience von Battisti, Nicolò Matteo Luca, Morrison, Laura, Nash, Tamsin, Senthivel, Nishanti, Kestenbaum, Samantha, Begum, Parvin, Obeid, Mariam, Hayhurst, William, Yang, Dorothy, Gafoor, Shafiah, Brown, Caroline, Rehman, Farah, Kenny, Laura, Hatcher, Olivia, Susan, Susan, Williams, Jennet, Brown, Anna, Rozati, Hamoun, Alexandros, Alexandros, Sawyer, Elinor, Gousis, Charalampos, Karapanagiotou, Eleni, Rigg, Anna, Rapti, Kleopatra, Roylance, Rebecca, Beresford, Mark, Gee, Abigail L, Konstantis, Apostolos, King, Judy, Nathan, Mark, Spurrell, Emma, Pearce, Mark, Bradwell, Dane, Denton, Arshi, Swain, Kate, McGrath, Sophie, Allen, Mark, Ring, Alistair, Johnston, Stephen, Raja, Fharat

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Fulvestrant in hormone receptor-positive advanced breast cancer: A UK retrospective multicenter study von Keshwani, Karim, lerner, anna, Sanderson, Benjamin, Board, Ruth E., Flynn, Michael, Sharkey, Elizabeth, Okines, Alicia Frances Clare, Konstantis, Apostolos, Roylance, Rebecca, Hanna, Daire, King, Judy, Murphy, Ravindhi, Rehman, Farah, Guppy, Amy Elizabeth, Westbury, Charlotte, Takeuchi, Elena, Spurrell, Emma, Raja, Fharat

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Development of the HT Me intervention to support women with breast cancer to adhere to adjuvant endocrine therapy and improve quality of life von Sarah-Jane F. Stewart, Joanna Slodkowska-Barabasz, Lucy McGeagh, Zoe Moon, Jo Brett, Mary Wells, Morven C. Brown, Mark Turner, Robert Horne, Deborah Fenlon, Farah Rehman, Henry Cain, Peter Donnelly, Victoria Harmer, Lesley Turner, Jan Rose, Linda Sharp, Eila Watson

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Y chromosome specific markers and the evolution of dioecy in the genus Silene von Zhang, Y. Hi, Stilio, Veronica S., Rehman, Farah, Avery, Amy, Mulcahy, David, Kesseli, Rick

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Developing rational drug combination strategies for PARP inhibitors von Rehman, Farah, Elliott, Richard, Brough, Rachel, Frankum, Jessica, Ragab, Anan, Lord, Christopher J., Ashworth, Alan

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Abstract A36: A transposon-based genetic screen in haploid mouse embryonic stem cells identifies Parp1 as a major mediator of olaparib toxicity von Pettitt, Stephen J., Rehman, Farah L., Bajrami, Ilirjana, Pemberton, Helen, Brough, Rachel, Kozarewa, Iwanka, Lord, Christopher J., Ashworth, Alan

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