Challenges and Opportunities in Adapting Clinical Trial Design for Immunotherapies von Siu, Lillian L, Ivy, S Percy, Dixon, Erica L, Gravell, Amy E, Reeves, Steven A, Rosner, Gary L

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SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis von Luthi-Carter, Ruth, Taylor, David M, Pallos, Judit, Lambert, Emmanuel, Amore, Allison, Parker, Alex, Moffitt, Hilary, Smith, Donna L, Runne, Heike, Gokce, Ozgun, Kuhn, Alexandre, Xiang, Zhongmin, Maxwell, Michele M, Reeves, Steven A, Bates, Gillian P, Neri, Christian, Thompson, Leslie M, Marsh, J. Lawrence, Kazantsev, Aleksey G

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Factors Affecting Combination Trial Success (FACTS): Investigator Survey Results on Early-Phase Combination Trials von Paller, Channing J, Huang, Erich P, Luechtefeld, Thomas, Massett, Holly A, Williams, Christopher C, Zhao, Jinxiu, Gravell, Amy E, Tamashiro, Tami, Reeves, Steven A, Rosner, Gary L, Carducci, Michael A, Rubinstein, Lawrence, Ivy, S Percy

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15d-PGJ2 induces apoptosis of mouse oligodendrocyte precursor cells von Xiang, Zhongmin, Lin, Tong, Reeves, Steven A

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Considerations on Integrating Prostate-Specific Membrane Antigen Positron Emission Tomography Imaging Into Clinical Prostate Cancer Trials by National Clinical Trials Network Coope... von Schöder, Heiko, Hope, Thomas A, Knopp, Michael, Kelly, William K, Michalski, Jeff M, Lerner, Seth P, Tawab-Amiri, Abdul, Mann, Bhupinder S, Lin, Daniel W, Yu, Evan Y, Chen, Ronald C, Beach, Gillian C, Reeves, Steven A, Shankar, Lalitha K

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Seamless Designs: Current Practice and Considerations for Early-Phase Drug Development in Oncology von Hobbs, Brian P, Barata, Pedro C, Kanjanapan, Yada, Paller, Channing J, Perlmutter, Jane, Pond, Gregory R, Prowell, Tatiana M, Rubin, Eric H, Seymour, Lesley K, Wages, Nolan A, Yap, Timothy A, Feltquate, David, Garrett-Mayer, Elizabeth, Grossman, William, Hong, David S, Ivy, S Percy, Siu, Lillian L, Reeves, Steven A, Rosner, Gary L

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Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease von Xiang, Zhongmin, Valenza, Marta, Cui, Libin, Leoni, Valerio, Jeong, Hyun-Kyung, Brilli, Elisa, Zhang, Jiangyang, Peng, Qi, Duan, Wenzhen, Reeves, Steven A, Cattaneo, Elena, Krainc, Dimitri

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Harnessing imaging tools to guide immunotherapy trials: summary from the National Cancer Institute Cancer Imaging Steering Committee workshop von Shankar, Lalitha K, Schöder, Heiko, Sharon, Elad, Wolchok, Jedd, Knopp, Michael V, Wahl, Richard L, Ellingson, Benjamin M, Hall, Nathan C, Yaffe, Martin J, Towbin, Alexander J, Farwell, Michael D, Pryma, Daniel, Poussaint, Tina Young, Wright, Chadwick L, Schwartz, Lawrence, Harisinghani, Mukesh, Mahmood, Umar, Wu, Anna M, Leung, David, de Vries, Elisabeth G E, Tang, Ying, Beach, Gillian, Reeves, Steven A

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Simvastatin induces cell death in a mouse cerebellar slice culture (CSC) model of developmental myelination von Xiang, Zhongmin, Reeves, Steven A.

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Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR von Yokogami, Kiyotaka, Wakisaka, Shinichiro, Avruch, Joseph, Reeves, Steven A.

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Regulated ectopic expression of cyclin D1 induces transcriptional activation of the cdk inhibitor p21 gene without altering cell cycle progression von HIYAMA, H, IAVARONE, A, LABAER, J, REEVES, S. A

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The protein tyrosine phosphatase SHP-2 negatively regulates ciliary neurotrophic factor induction of gene expression von Symes, Aviva, Stahl, Neil, Reeves, Steven A, Farruggella, Thomas, Servidei, Tiziana, Gearan, Tom, Yancopoulos, George, Fink, J.Stephen

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New mouse oligodendrocyte precursor (mOP) cells for studies on oligodendrocyte maturation and function von Lin, Tong, Xiang, Zhongmin, Cui, Libin, Stallcup, William, Reeves, Steven A.

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Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons von DiFiglia, Marian, Sapp, Ellen, Chase, Kathryn, Schwarz, Cordula, Meloni, Alison, Young, Christine, Martin, Eileen, Vonsattel, Jean-Paul, Carraway, Robert, Reeves, Steven A, Boyce, Frederick M, Aronin, Neil

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Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F von HIYAMA, H, IAVARONE, A, REEVES, S. A

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Detection of Myelination Using a Novel Histological Probe von Xiang, Zhongmin, Nesterov, Evgueni E, Skoch, Jesse, Lin, Tong, Hyman, Bradley T, Swager, Timothy M, Bacskai, Brian J, Reeves, Steven A

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Dual Control of Neurogenesis by PC3 through Cell Cycle Inhibition and Induction of Math1 von Canzoniere, Daniela, Farioli-Vecchioli, Stefano, Conti, Filippo, Ciotti, Maria Teresa, Tata, Ada Maria, Augusti-Tocco, Gabriella, Mattei, Elisabetta, Lakshmana, Madepalli K, Krizhanovsky, Valery, Reeves, Steven A, Giovannoni, Roberto, Castano, Francesca, Servadio, Antonio, Ben-Arie, Nissim, Tirone, Felice

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Role for cyclin D1 in UVC-induced and p53-mediated apoptosis von Hiyama, H, Reeves, S A

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Increased susceptibility to ischemia‐induced brain damage in transgenic mice overexpressing a dominant negative form of SHP2 von Aoki, Yoko, Huang, Zhihong, Thomas, Sunu S., Bhide, Pradeep G., Huang, Ivana, Moskowltz, Michael A., Reeves, Steven A.

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FACTS: Factors affecting combination trial success von Paller, Channing Judith, Huang, Erich, Luechtefeld, Thomas, Massett, Holly A., Williams, Christopher, Zhao, Jinxiu, Gravell, Amy, Reeves, Steven A., Rosner, Gary L., Carducci, Michael Anthony, Rubinstein, Larry, Ivy, S. Percy

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