Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing von Clancy, Danielle M., Sullivan, Graeme P., Moran, Hannah B.T., Henry, Conor M., Reeves, Emer P., McElvaney, Noel G., Lavelle, Ed C., Martin, Seamus J.

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Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α von Afonina, Inna S., Tynan, Graham A., Logue, Susan E., Cullen, Sean P., Bots, Michael, Lüthi, Alexander U., Reeves, Emer P., McElvaney, Noel G., Medema, Jan P., Lavelle, Ed C., Martin, Seamus J.

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A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy von Pohl, Kerstin, Hayes, Elaine, Keenan, Joanne, Henry, Michael, Meleady, Paula, Molloy, Kevin, Jundi, Bakr, Bergin, David A., McCarthy, Cormac, McElvaney, Oliver J., White, Michelle M., Clynes, Martin, Reeves, Emer P., McElvaney, Noel G.

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A Review of Alpha-1 Antitrypsin Binding Partners for Immune Regulation and Potential Therapeutic Application von O'Brien, Michael E, Murray, Grace, Gogoi, Debananda, Yusuf, Azeez, McCarthy, Cormac, Wormald, Mark R, Casey, Michelle, Gabillard-Lefort, Claudie, McElvaney, Noel G, Reeves, Emer P

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The vacuolar anti- Pseudomonal activity of neutrophil primary granule peptidyl-arginine deiminase enzymes von Baird, Rory, Yusuf, Azeez, Forde, Luke, Pohl, Kerstin, Kavanagh, Kevin, Fitzpatrick, Fidelma, Gogoi, Debananda, Reeves, Emer P

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Targeting of Glycosaminoglycans in Genetic and Inflammatory Airway Disease von Caird, Robin, Williamson, Michael, Yusuf, Azeez, Gogoi, Debananda, Casey, Michelle, McElvaney, Noel G., Reeves, Emer P.

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Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens von Kavanagh, Kevin, Reeves, Emer P.

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The Aspergillus fumigatus toxin fumagillin suppresses the immune response of Galleria mellonella larvae by inhibiting the action of haemocytes von FALLON, John P, REEVES, Emer P, KAVANAGH, Kevin

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Altered Degranulation and pH of Neutrophil Phagosomes Impacts Antimicrobial Efficiency in Cystic Fibrosis von Hayes, Elaine, Murphy, Mark P., Pohl, Kerstin, Browne, Niall, McQuillan, Karen, Saw, Le Er, Foley, Clare, Gargoum, Fatma, McElvaney, Oliver J., Hawkins, Padraig, Gunaratnam, Cedric, McElvaney, Noel G., Reeves, Emer P.

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Killing activity of neutrophils is mediated through activation of proteases by K + flux von Segal, Anthony W, Reeves, Emer P, Lu, Hui, Jacobs, Hugues Lortat, Messina, Carlo G. M, Bolsover, Steve, Gabella, Giorgio, Potma, Eric O, Warley, Alice, Roes, Jürgen

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Galectin-9 signaling through TIM-3 is involved in neutrophil-mediated Gram-negative bacterial killing: an effect abrogated within the cystic fibrosis lung von Vega-Carrascal, Isabel, Bergin, David A, McElvaney, Oliver J, McCarthy, Cormac, Banville, Nessa, Pohl, Kerstin, Hirashima, Mitsuomi, Kuchroo, Vijay K, Reeves, Emer P, McElvaney, Noel G

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Hypertonic Saline in Treatment of Pulmonary Disease in Cystic Fibrosis von Reeves, Emer P., Molloy, Kevin, Pohl, Kerstin, McElvaney, Noel G.

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Superoxide Production in Galleria mellonella Hemocytes: Identification of Proteins Homologous to the NADPH Oxidase Complex of Human Neutrophils von Bergin, David, Reeves, Emer P, Renwick, Julie, Wientjes, Frans B, Kavanagh, Kevin

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Targeting IgG Autoantibodies for Improved Cytotoxicity of Bactericidal Permeability Increasing Protein in Cystic Fibrosis von McQuillan, Karen, Gargoum, Fatma, Murphy, Mark P., McElvaney, Oliver J., McElvaney, Noel G., Reeves, Emer P.

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Alpha-1 Antitrypsin Augmentation Inhibits Proteolysis of Neutrophil Membrane Voltage-Gated Proton Channel-1 in Alpha-1 Deficient Individuals von Hawkins, Padraig, Sya, Julian, Hup, Nee Kee, Murphy, Mark P., McElvaney, Noel G., Reeves, Emer P.

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Inhibition of neutrophil function following exposure to the Aspergillus fumigatus toxin fumagillin von FALLON, John P, REEVES, Emer P, KAVANAGH, Kevin

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Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications von McElvaney, Oisin F., Asakura, Takanori, Meinig, Suzanne L., Torres-Castillo, Jose L., Hagan, Robert S., Gabillard-Lefort, Claudie, Murphy, Mark P., Thorne, Leigh B., Borczuk, Alain, Reeves, Emer P., Zumwalt, Ross E., Mikami, Yu, Carroll, Tomas P., Okuda, Kenichi, Hogan, Grace, McElvaney, Oliver J., Clarke, Jennifer, McEvoy, Natalie L., Mallon, Patrick W., McCarthy, Cormac, Curley, Ger, Wolfgang, Matthew C., Boucher, Richard C., McElvaney, Noel G.

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C3d Elicits Neutrophil Degranulation and Decreases Endothelial Cell Migration, with Implications for Patients with Alpha-1 Antitrypsin Deficiency von Fee, Laura T., Gogoi, Debananda, O'Brien, Michael E., McHugh, Emer, Casey, Michelle, Gough, Ciara, Murphy, Mark, Hopkins, Ann M., Carroll, Tomas P., McElvaney, Noel G., Reeves, Emer P.

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In vitro and in vivo modulation of NADPH oxidase activity and reactive oxygen species production in human neutrophils by α1-antitrypsin von Hawkins, Padraig, McEnery, Thomas, Gabillard-Lefort, Claudie, Bergin, David A, Alfawaz, Bader, Shutchaidat, Vipatsorn, Meleady, Paula, Henry, Michael, Coleman, Orla, Murphy, Mark, McElvaney, Noel G, Reeves, Emer P

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The Role of Neutrophils in Alpha-1 Antitrypsin Deficiency von McCarthy, Cormac, Reeves, Emer P, McElvaney, Noel G

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