Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction von England, Elizabeth, Rees, D. Gareth, Scott, Ian Christopher, Carmen, Sara, Chan, Denice T. Y., Chaillan Huntington, Catherine E., Houslay, Kirsty F., Erngren, Teodor, Penney, Mark, Majithiya, Jayesh B., Rapley, Laura, Sims, Dorothy A., Hollins, Claire, Hinchy, Elizabeth C., Strain, Martin D., Kemp, Benjamin P., Corkill, Dominic J., May, Richard D., Vousden, Katherine A., Butler, Robin J., Mustelin, Tomas, Vaughan, Tristan J., Lowe, David C., Colley, Caroline, Cohen, E. Suzanne

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A simeprevir-inducible molecular switch for the control of cell and gene therapies von Chin, Stacey E., Schindler, Christina, Vinall, Lisa, Dodd, Roger B., Bamber, Lisa, Legg, Sandrine, Sigurdardottir, Anna, Rees, D. Gareth, Malcolm, Tim I. M., Spratley, Samantha J., Granéli, Cecilia, Sumner, Jonathan, Tigue, Natalie J.

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Microemulsion-based media as novel drug delivery systems von Lawrence, M. Jayne, Rees, Gareth D.

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A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding von Douthwaite, Julie, Moisan, Jacques, Privezentzev, Cyril, Soskic, Blagoje, Sabbah, Shereen, Cohen, Suzanne, Collinson, Andie, England, Elizabeth, Huntington, Catherine, Kemp, Ben, Zhuang, Li, Hudak, Suzanne, Rees, D Gareth, Goldberg, Debbie, Barton, Chris, Chang, Linda, Vainshtein, Inna, Liang, Meina, Iciek, Laurie, Ambery, Philip, Peakman, Mark, Vaughan, Tristan J, Tree, Tim I M, Sansom, David M, Bowen, Michael A, Minter, Ralph R, Jermutus, Lutz

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Chitosan microparticles for the controlled delivery of fluoride von Keegan, Gemma M, Smart, John D, Ingram, Matthew J, Barnes, Lara-Marie, Burnett, Gary R, Rees, Gareth D

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Targeted protein degradation using chimeric human E2 ubiquitin-conjugating enzymes von Taylor, Jonathan D., Barrett, Nathalie, Martinez Cuesta, Sergio, Cassidy, Katelyn, Pachl, Fiona, Dodgson, James, Patel, Radhika, Eriksson, Tuula M., Riley, Aidan, Burrell, Matthew, Bauer, Christin, Rees, D. Gareth, Cimbro, Raffaello, Zhang, Andrew X., Minter, Ralph R., Hunt, James, Legg, Sandrine

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Affinity maturation of phage display antibody populations using ribosome display von Groves, Maria, Lane, Steven, Douthwaite, Julie, Lowne, David, Gareth Rees, D., Edwards, Bryan, Jackson, Ronald H.

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Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding von Douthwaite, Julie, Moisan, Jacques, Privezentzev, Cyril, Soskic, Blagoje, Sabbah, Shereen, Cohen, Suzanne, Collinson, Andie, England, Elizabeth, Huntington, Catherine, Kemp, Ben, Zhuang, Li, Hudak, Suzanne, Rees, D Gareth, Goldberg, Debbie, Barton, Chris, Chang, Linda, Vainshtein, Inna, Liang, Meina, Iciek, Laurie, Ambery, Philip, Peakman, Mark, Vaughan, Tristan J, Tree, Tim I M, Sansom, David M, Bowen, Michael A, Minter, Ralph R, Jermutus, Lutz

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Interactions between dodecyl phosphates and hydroxyapatite or tooth enamel: relevance to inhibition of dental erosion von Jones, Siân B, Barbour, Michele E, Shellis, R Peter, Rees, Gareth D

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MEDI1873, a potent, stabilized hexameric agonist of human GITR with regulatory T-cell targeting potential von Tigue, Natalie J., Bamber, Lisa, Andrews, John, Ireland, Samantha, Hair, James, Carter, Edward, Sridharan, Sudharsan, Jovanović, Jelena, Rees, D. Gareth, Springall, Jeremy S., Solier, Emilie, Li, Yi-Ming, Chodorge, Matthieu, Perez-Martinez, David, Higazi, Daniel R., Oberst, Michael, Kennedy, Maureen, Black, Chelsea M., Yan, Li, Schwickart, Martin, Maguire, Shaun, Cann, Jennifer A., de Haan, Lolke, Young, Lesley L., Vaughan, Tristan, Wilkinson, Robert W., Stewart, Ross

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A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthma von Cohen, E Suzanne, Dobson, Claire L, Käck, Helena, Wang, Bing, Sims, Dorothy A, Lloyd, Christopher O, England, Elizabeth, Rees, D Gareth, Guo, Hongwei, Karagiannis, Sophia N, O'Brien, Siobhan, Persdotter, Sofia, Ekdahl, Helena, Butler, Robin, Keyes, Feenagh, Oakley, Sarah, Carlsson, Mats, Briend, Emmanuel, Wilkinson, Trevor, Anderson, Ian K, Monk, Phillip D, von Wachenfeldt, Karin, Eriksson, Per-Olof F, Gould, Hannah J, Vaughan, Tristan J, May, Richard D

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1169 AZD5863: a specific, potent, affinity-optimized claudin 18.2 and CD3 binding T cell-engager that elicits low cytokine release and is capable of bystander killing von Gaspar, Miguel, Natoli, Marina, Castan, Laure, Rahmy, Sharif, Kelton, Cathryn, Mulgrew, Kathy, Korade, Martin, Huhn, Oisin, Gareth Rees, D, Sigurdardottir, Anna, Lloyd, Christopher, He, Yun, Rong, Yiping, Pollizzi, Kristen, Hammond, Scott, Cemerski, Saso, Dovedi, Simon, Cobbold, Mark, Ridgway, Benjamin, Broggi, Maria AS, Palmer, Douglas C, Ball, Kathryn, McFarlane, Mary, Vargas, Fred Arce, Ceaicovscaia, Natalia, Pouliot, Gayle, Szekeres, Philip, Fitzgerald, Jonathan, Kumar, Rakesh

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In vitro evolution of antibody affinity via insertional scanning mutagenesis of an entire antibody variable region von Skamaki, Kalliopi, Emond, Stephane, Chodorge, Matthieu, Andrews, John, Rees, D. Gareth, Cannon, Daniel, Popovic, Bojana, Buchanan, Andrew, Minter, Ralph R., Hollfelder, Florian

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Polymeric Microspheres for Drug Delivery to the Oral Cavity: An In Vitro Evaluation of Mucoadhesive Potential von Kockisch, Sandra, Rees, Gareth D., Young, Simon A., Tsibouklis, John, Smart, John D.

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Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation von Cohen, E. Suzanne, Scott, Ian C., Majithiya, Jayesh B., Rapley, Laura, Kemp, Benjamin P., England, Elizabeth, Rees, D. Gareth, Overed-Sayer, Catherine L., Woods, Joanne, Bond, Nicholas J., Veyssier, Christel Séguy, Embrey, Kevin J., Sims, Dorothy A., Snaith, Michael R., Vousden, Katherine A., Strain, Martin D., Chan, Denice T. Y., Carmen, Sara, Huntington, Catherine E., Flavell, Liz, Xu, Jianqing, Popovic, Bojana, Brightling, Christopher E., Vaughan, Tristan J., Butler, Robin, Lowe, David C., Higazi, Daniel R., Corkill, Dominic J., May, Richard D., Sleeman, Matthew A., Mustelin, Tomas

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Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex von Strickson, Sam, Houslay, Kirsty F., Negri, Victor A., Ohne, Yoichiro, Ottosson, Tomas, Dodd, Roger B., Huntington, Catherine Chaillan, Baker, Tina, Li, Jingjing, Stephenson, Katherine E., O’Connor, Andy J., Sagawe, J. Sophie, Killick, Helen, Moore, Tom, Rees, D. Gareth, Koch, Sofia, Sanden, Caroline, Wang, Yixin, Gubbins, Elise, Ghaedi, Mahboobe, Kolbeck, Roland, Saumyaa, Saumyaa, Erjefält, Jonas S., Sims, Gary P., Humbles, Alison A., Scott, Ian C., Ros, Xavier Romero, Cohen, E. Suzanne

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Formation and Morphology of Calcium Sulfate Nanoparticles and Nanowires in Water-in-Oil Microemulsions von Rees, Gareth D, Evans-Gowing, Richard, Hammond, Stephen J, Robinson, Brian H

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Microemulsion-based media as novel drug delivery systems von Lawrence, M.Jayne, Rees, Gareth D.

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Robust Prediction of Relative Binding Energies for Protein–Protein Complex Mutations Using Free Energy Perturbation Calculations von Sampson, Jared M., Cannon, Daniel A., Duan, Jianxin, Epstein, Jordan C.K., Sergeeva, Alina P., Katsamba, Phinikoula S., Mannepalli, Seetha M., Bahna, Fabiana A., Adihou, Hélène, Guéret, Stéphanie M., Gopalakrishnan, Ranganath, Geschwindner, Stefan, Rees, D. Gareth, Sigurdardottir, Anna, Wilkinson, Trevor, Dodd, Roger B., De Maria, Leonardo, Mobarec, Juan Carlos, Shapiro, Lawrence, Honig, Barry, Buchanan, Andrew, Friesner, Richard A., Wang, Lingle

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Novel quartz crystal microbalance based biosensor for detection of oral epithelial cell–microparticle interaction in real-time von Elsom, Jacqueline, Lethem, Michael I., Rees, Gareth D., Hunter, A. Christy

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