Overexpression of smad7 blocks primary tumor growth and lung metastasis development in osteosarcoma von Lamora, Audrey, Talbot, Julie, Bougras, Gwenola, Amiaud, Jérôme, Leduc, Marion, Chesneau, Julie, Taurelle, Julien, Stresing, Verena, Le Deley, Marie Cécile, Heymann, Marie Françoise, Heymann, Dominique, Redini, Françoise, Verrecchia, Franck

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Results of methotrexate-etoposide-ifosfamide based regimen (M-EI) in osteosarcoma patients included in the French OS2006/sarcome-09 study von Gaspar, Nathalie, Occean, Bob-Valéry, Pacquement, Hélène, Bompas, Emmanuelle, Bouvier, Corine, Brisse, Hervé J., Castex, Marie-Pierre, Cheurfa, Nadir, Corradini, Nadège, Delaye, Jessy, Entz-Werlé, Natacha, Gentet, Jean-Claude, Italiano, Antoine, Lervat, Cyril, Marec-Berard, Perrine, Mascard, Eric, Redini, Françoise, Saumet, Laure, Schmitt, Claudine, Tabone, Marie-Dominique, Verite-Goulard, Cécile, Le Deley, Marie-Cécile, Piperno-Neumann, Sophie, Brugieres, Laurence

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Current therapeutic strategies and novel approaches in osteosarcoma von Ando, Kosei, Heymann, Marie-Françoise, Stresing, Verena, Mori, Kanji, Rédini, Françoise, Heymann, Dominique

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Osteoprotegerin: Multiple partners for multiple functions von Baud’huin, Marc, Duplomb, Laurence, Teletchea, Stéphane, Lamoureux, François, Ruiz-Velasco, Carmen, Maillasson, Mike, Redini, Françoise, Heymann, Marie-Françoise, Heymann, Dominique

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12b80 – Hydroxybisphosphonate Linked Doxorubicin: Bone Targeted Strategy for Treatment of Osteosarcoma von David, Emmanuelle, Cagnol, Sébastien, Goujon, Jean-Yves, Egorov, Maxim, Taurelle, Julien, Benesteau, Charlène, Morandeau, Laëtitia, Moal, Christelle, Sicard, Marie, Pairel, Samuel, Heymann, Dominique, Redini, Françoise, Gouin, François, Le Bot, Ronan

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Therapeutic relevance of osteoprotegerin gene therapy in osteosarcoma : Blockade of the vicious cycle between tumor cell proliferation and bone resorption von LAMOUREUX, Francois, RICHARD, Peggy, REDINI, Francoise, WITTRANT, Yohann, BATTAGLIA, Séverine, PILET, Paul, TRICHET, Valérie, BLANCHARD, Frédéric, GOUIN, Francois, PITARD, Bruno, HEYMANN, Dominique

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TRAIL delivered by mesenchymal stromal/stem cells counteracts tumor development in orthotopic Ewing sarcoma models von Guiho, Romain, Biteau, Kevin, Grisendi, Giulia, Taurelle, Julien, Chatelais, Mathias, Gantier, Malika, Heymann, Dominique, Dominici, Massimo, Redini, Françoise

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Bone Tumor Environment as a Potential Therapeutic Target in Ewing Sarcoma von Redini, Françoise, Heymann, Dominique

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Imatinib mesylate exerts anti-proliferative effects on osteosarcoma cells and inhibits the tumour growth in immunocompetent murine models von Gobin, Bérengère, Moriceau, Gatien, Ory, Benjamin, Charrier, Céline, Brion, Régis, Blanchard, Frederic, Redini, Françoise, Heymann, Dominique

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Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases von Lamora, Audrey, Mullard, Mathilde, Amiaud, Jérôme, Brion, Régis, Heymann, Dominique, Redini, Françoise, Verrecchia, Franck

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Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis von Morice, Sarah, Danieau, Geoffroy, Tesfaye, Robel, Mullard, Mathilde, Brion, Régis, Dupuy, Maryne, Ory, Benjamin, Brounais-Le Royer, Bénédicte, Corre, Isabelle, Redini, Françoise, Verrecchia, Franck

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Oncostatin M Is a Growth Factor for Ewing Sarcoma von David, Emmanuelle, Tirode, Franck, Baud'huin, Marc, Guihard, Pierre, Laud, Karine, Delattre, Olivier, Heymann, Marie F, Heymann, Dominique, Redini, Françoise, Blanchard, Frédéric

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BYL719, a new α‐specific PI3K inhibitor: Single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma von Gobin, Bérengère, Huin, Marc Baud', Lamoureux, François, Ory, Benjamin, Charrier, Céline, Lanel, Rachel, Battaglia, Séverine, Redini, Françoise, Lezot, Frédéric, Blanchard, Frédéric, Heymann, Dominique

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In vitro and in vivo discrepancy in inducing apoptosis by mesenchymal stromal cells delivering membrane-bound tumor necrosis factor–related apoptosis inducing ligand in osteosarcom... von Guiho, ROMAIN, BITEAU, KEVIN, GRISENDI, GIULIA, CHATELAIS, MATHIAS, BRION, REGIS, TAURELLE, JULIEN, RENAULT, SARAH, HEYMANN, DOMINIQUE, DOMINICI, MASSIMO, REDINI, FRANÇOISE

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Immune Infiltrate and Tumor Microenvironment Transcriptional Programs Stratify Pediatric Osteosarcoma into Prognostic Groups at Diagnosis von Marchais, Antonin, Marques da Costa, Maria Eugenia, Job, Bastien, Abbas, Rachid, Drubay, Damien, Piperno-Neumann, Sophie, Fromigué, Olivia, Gomez-Brouchet, Anne, Redini, Françoise, Droit, Robin, Lervat, Cyril, Entze-Werle, Natacha, Pacquement, Hélène, Devoldere, Catherine, Cupissol, Didier, Bodet, Damien, Gandemer, Virginie, Berger, Marc, Marec-Berard, Perrine, Jimenez, Marta, Vassal, Gilles, Geoerger, Birgit, Brugières, Laurence, Gaspar, Nathalie

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Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment von Verrecchia, Franck, Rédini, Françoise

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Severe Compromise of Preosteoblasts in a Surgical Mouse Model of Bisphosphonate-Associated Osteonecrosis of the Jaw von Córdova, Luis A., DDS, PhD, Guilbaud, Florian, BSc, Amiaud, Jérôme, BSc, Battaglia, Séverine, BSc, Charrier, Céline, BSc, Lezot, Frédéric, PhD, Piot, Benoît, MD, PhD, Redini, Françoise, PhD, Heymann, Dominique, PhD

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The Osteosarcoma Microenvironment: A Complex But Targetable Ecosystem von Corre, Isabelle, Verrecchia, Franck, Crenn, Vincent, Redini, Francoise, Trichet, Valérie

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Impact of oncopediatric dosing regimen of zoledronic acid on bone growth: Preclinical studies and case report of an osteosarcoma pediatric patient von Battaglia, Séverine, Dumoucel, Sophie, Chesneau, Julie, Heymann, Marie‐Françoise, Picarda, Gaëlle, Gouin, François, Corradini, Nadège, Heymann, Dominique, Redini, Françoise

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TRAIL-based therapy in pediatric bone tumors: how to overcome resistance von Guiho, Romain, Biteau, Kevin, Heymann, Dominique, Redini, Françoise

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