The folate receptor as a rational therapeutic target for personalized cancer treatment von Assaraf, Yehuda G, Leamon, Christopher P, Reddy, Joseph A

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Pre-clinical evaluation of EC1456, a folate-tubulysin anti-cancer therapeutic von Reddy, Joseph A., Dorton, Ryan, Bloomfield, Alicia, Nelson, Melissa, Dircksen, Christina, Vetzel, Marilynn, Kleindl, Paul, Santhapuram, Hari, Vlahov, Iontcho R., Leamon, Christopher P.

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Pre-clinical studies of EC2629, a highly potent folate- receptor-targeted DNA crosslinking agent von Reddy, Joseph A., Nelson, Melissa, Dircksen, Christina, Vetzel, Marilynn, Johnson, Theresa, Cross, Vicky, Westrick, Elaine, Qi, LongWu, Hahn, Spencer, Santhapuram, Hari Krishna, Parham, Garth, Wang, Kevin, Vaughn, Jeremy F., Felten, Albert, Pugh, Michael, Lu, June, Klein, Patrick, Vlahov, Iontcho R., Leamon, Christopher P.

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Preclinical evaluation of EC145, a folate-Vinca alkaloid conjugate von REDDY, Joseph A, DORTON, Ryan, WESTRICK, Elaine, DAWSON, Alicia, SMITH, Terri, XU, Le-Cun, VETZEL, Marilynn, KLEINDL, Paul, VLAHOV, Iontcho R, LEAMON, Christopher P

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Ligand Binding and Kinetics of Folate Receptor Recycling in Vivo: Impact on Receptor-Mediated Drug Delivery von Paulos, Chrystal M, Reddy, Joseph A, Leamon, Christopher P, Turk, Mary Jo, Low, Philip S

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Targeting Folate Receptors to Treat Invasive Urinary Bladder Cancer von DHAWAN, Deepika, RAMOS-VARA, Jose A, REDDY, Joseph A, KOCH, Michael, MURPHY, Linda, FOUREZ, Lindsey M, STEWART, Jane C, KNAPP, Deborah W, NAUGHTON, James F, LIANG CHENG, LOW, Philip S, ROTHENBUHLER, Ryan, LEAMON, Christopher P, PARKER, Nikki, KLEIN, Patrick J, VLAHOV, Lontcho R

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High Levels of Expression of P-glycoprotein/Multidrug Resistance Protein Result in Resistance to Vintafolide von Guertin, Amy D, O'Neil, Jennifer, Stoeck, Alexander, Reddy, Joseph A, Cristescu, Razvan, Haines, Brian B, Hinton, Marlene C, Dorton, Ryan, Bloomfield, Alicia, Nelson, Melissa, Vetzel, Marilynn, Lejnine, Serguei, Nebozhyn, Michael, Zhang, Theresa, Loboda, Andrey, Picard, Kristen L, Schmidt, Emmett V, Dussault, Isabelle, Leamon, Christopher P

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Comparative preclinical activity of the folate‐targeted Vinca alkaloid conjugates EC140 and EC145 von Leamon, Christopher P., Reddy, Joseph A., Vlahov, Iontcho R., Westrick, Elaine, Parker, Nikki, Nicoson, Jeffrey S., Vetzel, Marilynn

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Surface modification technique to enhance metallurgical and mechanical properties of alloy C-276 weldment by laser shock peening without coating von Nithin Joseph Reddy, S A, Thrinadh, E, Prabhakaran, S, Kalainathan, S, Arivazhagan, N, Manikandan, M

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Folate-targeted chemotherapy von Leamon, Christopher P, Reddy, Joseph A

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Prostate-Specific Membrane Antigen-Specific Antitumor Activity of a Self-Immolative Tubulysin Conjugate von Leamon, Christopher P, Reddy, Joseph A, Bloomfield, Alicia, Dorton, Ryan, Nelson, Melissa, Vetzel, Marilynn, Kleindl, Paul, Hahn, Spencer, Wang, Kevin, Vlahov, Iontcho R

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Preclinical pharmacokinetics, tissue distribution, and antitumor activity of a folate-hapten conjugate–targeted immunotherapy in hapten-immunized mice von Lu, Yingjuan, Xu, Le-Cun, Parker, Nikki, Westrick, Elaine, Reddy, Joseph A, Vetzel, Marilynn, Low, Philip S, Leamon, Christopher P

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An Assembly Concept for the Consecutive Introduction of Unsymmetrical Disulfide Bonds:  Synthesis of a Releasable Multidrug Conjugate of Folic Acid von Vlahov, Iontcho R, Santhapuram, Hari Krishna R, Wang, Yu, Kleindl, Paul J, You, Fei, Howard, Stephen J, Westrick, Elaine, Reddy, Joseph A, Leamon, Christopher P

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Rational Combination Therapy of Vintafolide (EC145) with Commonly Used Chemotherapeutic Drugs von REDDY, Joseph A, DORTON, Ryan, BLOOMFIELD, Alicia, NELSON, Melissa, VETZEL, Marilynn, GUAN, John, LEAMON, Christopher P

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Folate–Vinca Alkaloid Conjugates for Cancer Therapy: A Structure–Activity Relationship von Leamon, Christopher P, Vlahov, Iontcho R, Reddy, Joseph A, Vetzel, Marilynn, Santhapuram, Hari Krishna R, You, Fei, Bloomfield, Alicia, Dorton, Ryan, Nelson, Melissa, Kleindl, Paul, Vaughn, Jeremy F, Westrick, Elaine

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Folate targeting enables durable and specific antitumor responses from a therapeutically null tubulysin B analogue von Leamon, Christopher P, Reddy, Joseph A, Vetzel, Marilynn, Dorton, Ryan, Westrick, Elaine, Parker, Nikki, Wang, Yu, Vlahov, Iontcho

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Detecting Functional and Accessible Folate Receptor Expression in Cancer and Polycystic Kidneys von Chu, Haiyan, Shillingford, Jonathan M, Reddy, Joseph A, Westrick, Elaine, Nelson, Melissa, Wang, Emilia Z, Parker, Nikki, Felten, Albert E, Vaughn, Jeremy F, Xu, Le-Cun, Lu, Yingjuan J, Vlahov, Iontcho R, Leamon, Christopher P

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Preclinical Antitumor Activity of a Novel Folate-Targeted Dual Drug Conjugate von Leamon, Christopher P, Reddy, Joseph A, Vlahov, Iontcho R, Westrick, Elaine, Dawson, Alicia, Dorton, Ryan, Vetzel, Marilynn, Santhapuram, Hari Krishna, Wang, Yu

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Abstract 3754: Pre-clinical studies of a highly potent folate receptor targeted DNA crosslinking agent von Reddy, Joseph A., Nelson, Melissa, Johnson, Theresa, Dirksen, Christina, Vetzel, Marilynn, Hahn, Spencer, Qi, LongWu, Vlahov, Iontcho, Leamon, Christopher

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Enhancing the therapeutic range of a targeted small-molecule tubulysin conjugate for folate receptor-based cancer therapy von Leamon, Christopher P., Reddy, Joseph A., Vlahov, Iontcho R., Dorton, Ryan, Bloomfield, Alicia, Vetzel, Marilynn, Klein, Patrick J., Westrick, Elaine, Xu, Le-cun, Wang, Yu

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