Alanine aminotransferase isoenzymes: Molecular cloning and quantitative analysis of tissue expression in rats and serum elevation in liver toxicity von Yang, Rong‐Ze, Park, Soohyun, Reagan, William J., Goldstein, Rick, Zhong, Shao, Lawton, Michael, Rajamohan, Francis, Qian, Kun, Liu, Li, Gong, Da‐Wei

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Effects of Monoclonal Antibodies against Nerve Growth Factor on Healthy Bone and Joint Tissues in Mice, Rats, and Monkeys: Histopathologic, Biomarker, and Microcomputed Tomographic... von Gropp, Kathryn E., Carlson, Cathy S., Evans, Mark G., Bagi, Cedo M., Reagan, William J., Hurst, Susan I., Shelton, David L., Zorbas, Mark A.

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To Clot or Not to Clot: Deepening Our Understanding of Alterations in the Hemostatic System von Reagan, William J., Brooks, Marjory B., Grozovsky, Renata, Pittman, Debra, Vitsky, Allison, Brenneman, Karrie

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A translational approach to detecting drug-induced cardiac injury with cardiac troponins: Consensus and recommendations from the Cardiac Troponins Biomarker Working Group of the He... von Berridge, Brian R., DVM, PhD, Pettit, Syril, MS, Walker, Dana B., DVM, PhD, Jaffe, Alan S., MD, Schultze, Albert E., DVM, PhD, Herman, Eugene, PhD, Reagan, William J., DVM, PhD, Lipshultz, Steven E., MD, Apple, Fred S., PhD, York, Malcolm J., MPhil

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Comparison of Cardiac Troponin I and T, Including the Evaluation of an Ultrasensitive Assay, as Indicators of Doxorubicin-induced Cardiotoxicity von Reagan, William J., York, Malcolm, Berridge, Brian, Schultze, Eric, Walker, Dana, Pettit, Syril

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Circulating microRNAs as promising testicular translatable safety biomarkers: current state and future perspectives von Zhang, Jiangwei, Campion, Sarah, Catlin, Natasha, Reagan, William J., Palyada, Kiran, Ramaiah, Shashi K., Ramanathan, Ragu

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Troponin as a Biomarker of Cardiac Toxicity: Past, Present, and Future von Reagan, William J.

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Evaluation of Rat Acute Phase Proteins as Inflammatory Biomarkers for Vaccine Nonclinical Safety Studies von Reagan, William J., Shoieb, Ahmed M., Schomaker, Shelli J., Markiewicz, Victoria R., Clarke, David W., Sellers, Rani S.

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Comprehensive Nonclinical Safety Assessment of Nirmatrelvir Supporting Timely Development of the SARS-COV-2 Antiviral Therapeutic, Paxlovid von Sathish, Jean G., Bhatt, Siddhartha, DaSilva, Jamie K., Flynn, Declan, Jenkinson, Stephen, Kalgutkar, Amit S., Liu, Maggie, Manickam, Balasubramanian, Pinkstaff, Jason, Reagan, William J., Shirai, Norimitsu, Shoieb, Ahmed M., Sirivelu, Madhu, Vispute, Saurabh, Vitsky, Allison, Walters, Karen, Wisialowski, Todd A., Updyke, Lawrence W.

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Assessment of Cardiac Troponin I Responses in Nonhuman Primates during Restraint, Blood Collection, and Dosing in Preclinical Safety Studies von Reagan, William J., Barnes, Robert, Harris, Peter, Summers, Sandy, Lopes, Sarah, Stubbs, Makeida, Blackwell, David, Steidl-Nichols, Jill

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Principles for Assessing Adversity in Toxicologic Clinical Pathology von Ramaiah, Lila, Tomlinson, Lindsay, Tripathi, Niraj K., Cregar, Laura C., Vitsky, Allison, Beust, Barbara von, Barlow, Valerie G., Reagan, William J., Ennulat, Daniela

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Expression, purification, and initial characterization of human alanine aminotransferase (ALT) isoenzyme 1 and 2 in High-five insect cells von Liu, Li, Zhong, Shao, Yang, Rongze, Hu, Hong, Yu, Daozhan, Zhu, Dalong, Hua, Zichun, Shuldiner, Alan R., Goldstein, Richard, Reagan, William J., Gong, Da-Wei

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Analytic Evaluation of a Human ELISA Kit for Measurement of Inhibin B in Rat Samples von Coulson, Michelle, Bickerton, Sue, Betts, Catherine J, Jacobsen, Matt, Stewart, Jane, Chapin, Robert E., Reagan, William J., Alvey, James, Erdos, Zoltan, Saldutti, Louise Parks, Sonee, Manisha, Bogdan, Nancy, Singer, Monica, Vinken, Petra, Barlow, Valerie, Czajkowski, Karen, Kim, James H.

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Confounding Factors in the Interpretation of Preclinical Studies von Morton, Laura Dill, Sanders, Martin, Reagan, William J., Crabbs, Torrie A., McVean, Maralee, Funk, Kathleen A.

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Evaluation of Cardiac Toxicity Biomarkers in Rats from Different Laboratories von Kim, Kyuri, Chini, Naseem, Fairchild, David G., Engle, Steven K., Reagan, William J., Summers, Sandra D., Mirsalis, Jon C.

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The use of emerging safety biomarkers in nonclinical and clinical safety assessment – The current and future state: An IQ DruSafe industry survey von Zabka, Tanja S., Burkhardt, John, Reagan, William J., Gautier, Jean-Charles, Glaab, Warren E., Guffroy, Magali, Harding, Joanna, Brees, Dominique, McDuffie, Eric, Ramaiah, Lila, Schultze, A. Eric, Smith, James D., Wolfreys, Alison, Dalmas, Deidre A.

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Metabolic Adaptive ALT Isoenzyme Response in Livers of C57/BL6 Mice Treated with Dexamethasone von Reagan, William J., Yang, Rong-Ze, Park, Soohyun, Goldstein, Richard, Brees, Dominique, Gong, Da-Wei

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Toxicities Associated with 1-month Treatment with Propylthiouracil (PTU) and Methimazole (MMI) in Male Rats von Nambiar, Prashant R., Palanisamy, Gopinath S., Okerberg, Carlin, Wolford, Angela, Walters, Karen, Buckbinder, Leonard, Reagan, William J.

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De novo lipogenesis is essential for platelet production in humans von Kelly, Kenneth L., Reagan, William J., Sonnenberg, Gabriele E., Clasquin, Michelle, Hales, Katherine, Asano, Shoh, Amor, Paul A., Carvajal-Gonzalez, Santos, Shirai, Norimitsu, Matthews, Marcy D., Li, Kelvin W., Hellerstein, Marc K., Vera, Nicholas B., Ross, Trenton T., Cappon, Gregg, Bergman, Arthur, Buckeridge, Clare, Sun, Zhongyuan, Qejvanaj, Enida Ziso, Schmahai, Theodore, Beebe, David, Pfefferkorn, Jeffrey A., Esler, William P.

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The American Society for Veterinary Clinical Pathology Regulatory Affairs Committee's clinical pathology best practices recommendations will impact the discipline of veterinary tox... von Reagan, William J.

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