Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19 von Rodda, Lauren B., Netland, Jason, Shehata, Laila, Pruner, Kurt B., Morawski, Peter A., Thouvenel, Christopher D., Takehara, Kennidy K., Eggenberger, Julie, Hemann, Emily A., Waterman, Hayley R., Fahning, Mitchell L., Chen, Yu, Hale, Malika, Rathe, Jennifer, Stokes, Caleb, Wrenn, Samuel, Fiala, Brooke, Carter, Lauren, Hamerman, Jessica A., King, Neil P., Gale, Michael, Campbell, Daniel J., Rawlings, David J., Pepper, Marion

Volltext

B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity von Arkatkar, Tanvi, Du, Samuel W, Jacobs, Holly M, Dam, Elizabeth M, Hou, Baidong, Buckner, Jane H, Rawlings, David J, Jackson, Shaun W

Volltext

Somatically Hypermutated Plasmodium-Specific IgM+ Memory B Cells Are Rapid, Plastic, Early Responders upon Malaria Rechallenge von Krishnamurty, Akshay T., Thouvenel, Christopher D., Portugal, Silvia, Keitany, Gladys J., Kim, Karen S., Holder, Anthony, Crompton, Peter D., Rawlings, David J., Pepper, Marion

Volltext

The role of PTPN22 risk variant in the development of autoimmunity: finding common ground between mouse and human von Rawlings, David J, Dai, Xuezhi, Buckner, Jane H

Volltext

Engineering Protein-Secreting Plasma Cells by Homology-Directed Repair in Primary Human B Cells von Hung, King L., Meitlis, Iana, Hale, Malika, Chen, Chun-Yu, Singh, Swati, Jackson, Shaun W., Miao, Carol H., Khan, Iram F., Rawlings, David J., James, Richard G.

Volltext

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22 von Spalinger, Marianne R, Kasper, Stephanie, Gottier, Claudia, Lang, Silvia, Atrott, Kirstin, Vavricka, Stephan R, Scharl, Sylvie, Raselli, Tina, Frey-Wagner, Isabelle, Gutte, Petrus M, Grütter, Markus G, Beer, Hans-Dietmar, Contassot, Emmanuel, Chan, Andrew C, Dai, Xuezhi, Rawlings, David J, Mair, Florian, Becher, Burkhard, Falk, Werner, Fried, Michael, Rogler, Gerhard, Scharl, Michael

Volltext

A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models von Dai, Xuezhi, James, Richard G, Habib, Tania, Singh, Swati, Jackson, Shaun, Khim, Socheath, Moon, Randall T, Liggitt, Denny, Wolf-Yadlin, Alejandro, Buckner, Jane H, Rawlings, David J

Volltext

Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation von Jackson, Shaun W, Scharping, Nicole E, Kolhatkar, Nikita S, Khim, Socheath, Schwartz, Marc A, Li, Quan-Zhen, Hudkins, Kelly L, Alpers, Charles E, Liggitt, Denny, Rawlings, David J

Volltext

B cells take the front seat: dysregulated B cell signals orchestrate loss of tolerance and autoantibody production von Jackson, Shaun W, Kolhatkar, Nikita S, Rawlings, David J

Volltext

Novel Suppressive Function of Transitional 2 B Cells in Experimental Arthritis von Evans, Jamie G, Chavez-Rueda, Karina A, Eddaoudi, Ayad, Meyer-Bahlburg, Almut, Rawlings, David J, Ehrenstein, Michael R, Mauri, Claudia

Volltext

Activated PIK3CD drives innate B cell expansion yet limits B cell-intrinsic immune responses von Wray-Dutra, Michelle N, Al Qureshah, Fahd, Metzler, Genita, Oukka, Mohamed, James, Richard G, Rawlings, David J

Volltext

SEC-seq: association of molecular signatures with antibody secretion in thousands of single human plasma cells von Cheng, Rene Yu-Hong, de Rutte, Joseph, Ito, Cade Ellis K., Ott, Andee R., Bosler, Lucie, Kuo, Wei-Ying, Liang, Jesse, Hall, Brian E., Rawlings, David J., Di Carlo, Dino, James, Richard G.

Volltext

Ex vivo engineered human plasma cells exhibit robust protein secretion and long-term engraftment in vivo von Cheng, Rene Yu-Hong, Hung, King L., Zhang, Tingting, Stoffers, Claire M., Ott, Andee R., Suchland, Emmaline R., Camp, Nathan D., Khan, Iram F., Singh, Swati, Yang, Ying-Jen, Rawlings, David J., James, Richard G.

Volltext

In Vivo Outcome of Homology-Directed Repair at the HBB Gene in HSC Using Alternative Donor Template Delivery Methods von Pattabhi, Sowmya, Lotti, Samantha N., Berger, Mason P., Singh, Swati, Lux, Christopher T., Jacoby, Kyle, Lee, Calvin, Negre, Olivier, Scharenberg, Andrew M., Rawlings, David J.

Volltext

Germline SAMD9L truncation variants trigger global translational repression von Allenspach, Eric J, Soveg, Frank, Finn, Laura S, So, Lomon, Gorman, Jacquelyn A, Rosen, Aaron B I, Skoda-Smith, Suzanne, Wheeler, Marsha M, Barrow, Kaitlyn A, Rich, Lucille M, Debley, Jason S, Bamshad, Michael J, Nickerson, Deborah A, Savan, Ram, Torgerson, Troy R, Rawlings, David J

Volltext

Cutting Edge: BAFF Overexpression Reduces Atherosclerosis via TACI-Dependent B Cell Activation von Jackson, Shaun W, Scharping, Nicole E, Jacobs, Holly M, Wang, Shari, Chait, Alan, Rawlings, David J

Volltext

Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells von Wang, Cathy X., Sather, Blythe D., Wang, Xuefeng, Adair, Jennifer, Khan, Iram, Singh, Swati, Lang, Shanshan, Adams, Amie, Curinga, Gabrielle, Kiem, Hans-Peter, Miao, Carol H., Rawlings, David J., Torbett, Bruce E.

Volltext

Optimizing lentiviral vector transduction of hematopoietic stem cells for gene therapy von Jang, Yoonjeong, Kim, Yoon-Sang, Wielgosz, Matthew M., Ferrara, Francesca, Ma, Zhijun, Condori, Jose, Palmer, Lance E., Zhao, Xiwen, Kang, Guolian, Rawlings, David J., Zhou, Sheng, Ryu, Byoung Y.

Volltext

PTPN22 R620W gene editing in T cells enhances low-avidity TCR responses von Anderson, Warren, Barahmand-Pour-Whitman, Fariba, Linsley, Peter S, Cerosaletti, Karen, Buckner, Jane H, Rawlings, David J

Volltext

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22 von Spalinger, Marianne R, Kasper, Stephanie, Gottier, Claudia, Lang, Silvia, Atrott, Kirstin, Vavricka, Stephan R, Scharl, Sylvie, Gutte, Petrus M, Grütter, Markus G, Beer, Hans-Dietmar, Contassot, Emmanuel, Chan, Andrew C, Dai, Xuezhi, Rawlings, David J, Mair, Florian, Becher, Burkhard, Falk, Werner, Fried, Michael, Rogler, Gerhard, Scharl, Michael

Volltext