Beyond Hox: the role of ParaHox genes in normal and malignant hematopoiesis von Rawat, Vijay P.S., Humphries, R. Keith, Buske, Christian

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Differences in expression and function of LEF1 isoforms in normal versus leukemic hematopoiesis von Feder, Kristin, Edmaier-Schröger, Katrin, Rawat, Vijay P. S., Kirsten, Nicole, Metzeler, Klaus, Kraus, Johann M., Döhner, Konstanze, Döhner, Hartmut, Kestler, Hans A., Feuring-Buske, Michaela, Buske, Christian

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The microRNA miR-196b acts as a tumor suppressor in Cdx2-driven acute myeloid leukemia von Rawat, Vijay P S, Götze, Maria, Rasalkar, Avinash, Vegi, Naidu M, Ihme, Susann, Thoene, Silvia, Pastore, Alessandro, Bararia, Deepak, Döhner, Hartmut, Döhner, Konstanze, Feuring-Buske, Michaela, Quintanilla-Fend, Leticia, Buske, Christian

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High expression of lymphoid enhancer-binding factor-1 (LEF1) is a novel favorable prognostic factor in cytogenetically normal acute myeloid leukemia von Metzeler, Klaus H., Heilmeier, Bernhard, Edmaier, Katrin E., Rawat, Vijay P.S., Dufour, Annika, Döhner, Konstanze, Feuring-Buske, Michaela, Braess, Jan, Spiekermann, Karsten, Büchner, Thomas, Sauerland, Maria C., Döhner, Hartmut, Hiddemann, Wolfgang, Bohlander, Stefan K., Schlenk, Richard F., Bullinger, Lars, Buske, Christian

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vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia von Rawat, Vijay P.S, Arseni, Natalia, Ahmed, Farid, Mulaw, Medhanie A, Thoene, Silvia, Heilmeier, Bernhard, Sadlon, Tim, D'Andrea, Richard J, Hiddemann, Wolfgang, Bohlander, Stefan K, Buske, Christian, Feuring-Buske, Michaela

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MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML von Vegi, Naidu M., Klappacher, Josef, Oswald, Franz, Mulaw, Medhanie A., Mandoli, Amit, Thiel, Verena N., Bamezai, Shiva, Feder, Kristin, Martens, Joost H.A., Rawat, Vijay P.S., Mandal, Tamoghna, Quintanilla-Martinez, Leticia, Spiekermann, Karsten, Hiddemann, Wolfgang, Döhner, Konstanze, Döhner, Hartmut, Stunnenberg, Hendrik G., Feuring-Buske, Michaela, Buske, Christian

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A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis von Petropoulos, Konstantin, Arseni, Natalia, Schessl, Christina, Stadler, Christiane R, Rawat, Vijay P S, Deshpande, Aniruddha J, Heilmeier, Bernhard, Hiddemann, Wolfgang, Quintanilla-Martinez, Leticia, Bohlander, Stefan K, Feuring-Buske, Michaela, Buske, Christian

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Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human... von Rawat, Vijay P.S., Thoene, Silvia, Naidu, Vegi M., Arseni, Natalia, Heilmeier, Bernhard, Metzeler, Klaus, Petropoulos, Konstantin, Deshpande, Aniruddha, Quintanilla-Martinez, Leticia, Bohlander, Stefan K., Spiekermann, Karsten, Hiddemann, Wolfgang, Feuring-Buske, Michaela, Buske, Christian

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TET3 promotes AML growth and epigenetically regulates glucose metabolism and leukemic stem cell associated pathways von Pulikkottil, Alex Jose, Bamezai, Shiva, Ammer, Tobias, Mohr, Fabian, Feder, Kristin, Vegi, Naidu M., Mandal, Tamoghna, Kohlhofer, Ursula, Quintanilla-Martinez, Leticia, Sinha, Amit, Buske, Christian, Rawat, Vijay P. S.

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Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia von Deshpande, Aniruddha J., Cusan, Monica, Rawat, Vijay P.S., Reuter, Hendrik, Krause, Alexandre, Pott, Christiane, Quintanilla-Martinez, Leticia, Kakadia, Purvi, Kuchenbauer, Florian, Ahmed, Farid, Delabesse, Eric, Hahn, Meinhard, Lichter, Peter, Kneba, Michael, Hiddemann, Wolfgang, Macintyre, Elizabeth, Mecucci, Cristina, Ludwig, Wolf-Dieter, Humphries, R. Keith, Bohlander, Stefan K., Feuring-Buske, Michaela, Buske, Christian

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TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition von Bamezai, Shiva, Demir, Deniz, Pulikkottil, Alex Jose, Ciccarone, Fabio, Fischbein, Elena, Sinha, Amit, Borga, Chiara, te Kronnie, Geertruy, Meyer, Lüder-Hinrich, Mohr, Fabian, Götze, Maria, Caiafa, Paola, Debatin, Klaus-Michael, Döhner, Konstanze, Döhner, Hartmut, González-Menéndez, Irene, Quintanilla-Fend, Leticia, Herold, Tobias, Jeremias, Irmela, Feuring-Buske, Michaela, Buske, Christian, Rawat, Vijay P. S.

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Concise Review: The Piwi-piRNA Axis: Pivotal Beyond Transposon Silencing von Bamezai, Shiva, Rawat, Vijay P.S., Buske, Christian

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Ectopic Expression of the Homeobox Gene Cdx2 Is the Transforming Event in a Mouse Model of t(12;13)(p13;q12) Acute Myeloid Leukemia von Vijay P. S. Rawat, Cusan, Monica, Deshpande, Aniruddha, Hiddemann, Wolfgang, Quintanilla-Martinez, Leticia, Humphries, R. Keith, Bohlander, Stefan K., Feuring-Buske, Michaela, Buske, Christian

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A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML von Bamezai, Shiva, Pulikkottil, Alex Jose, Yadav, Tribhuwan, Vegi, Naidu M., Mueller, Julia, Mark, Jasmin, Mandal, Tamoghna, Feder, Kristin, Ihme, Susann, Song, Chenlin, Rosler, Reinhild, Wiese, Sebastian, Hoell, Jessica I., Kloetgen, Andreas, Karsan, Aly, Kumari, Ankita, Wojenski, Luke, Sinha, Amit U., Gonzalez-Menendez, Irene, Quintanilla-Martinez, Leticia, Donato, Elisa, Trumpp, Andreas, Kruse, Elisabeth, Hamperl, Stephan, Zou, Lee, Rawat, Vijay P. S., Buske, Christian

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TET Genes: new players in DNA demethylation and important determinants for stemness von Mohr, Fabian, Döhner, Konstanze, Buske, Christian, Rawat, Vijay P.S

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Somatostatin receptor mediated targeting of acute myeloid leukemia by photodynamic metal complexes for light induced apoptosis von Vegi, Naidu M., Chakrabortty, Sabyasachi, Zegota, Maksymilian M., Kuan, Seah Ling, Stumper, Anne, Rawat, Vijay P. S., Sieste, Stefanie, Buske, Christian, Rau, Sven, Weil, Tanja, Feuring-Buske, Michaela

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Targeting of CXCR4 by the Naturally Occurring CXCR4 Antagonist EPI-X4 in Waldenström's Macroglobulinemia von Kaiser, Lisa Marie, Harms, Mirja, Sauter, Daniel, Rawat, Vijay P S, Glitscher, Mirco, Hildt, Eberhard, Tews, Daniel, Hunter, Zachary, Münch, Jan, Buske, Christian

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Npm1 haploinsufficiency in collaboration with MEIS1 is sufficient to induce AML in mice von Muranyi, Andrew, Ammer, Tobias, Kechter, Anna, Rawat, Vijay P. S., Sinha, Amit, Gonzalez-Menendez, Irene, Quintanilla-Martinez, Leticia, Azoitei, Anca, Günes, Cagatay, Mupo, Annalisa, Vassiliou, George, Bamezai, Shiva, Buske, Christian

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VENTX induces expansion of primitive erythroid cells and contributes to the development of acute myeloid leukemia in mice von Gentner, Eva, Vegi, Naidu M, Mulaw, Medhanie A, Mandal, Tamoghna, Bamezai, Shiva, Claus, Rainer, Tasdogan, Alpaslan, Quintanilla-Martinez, Leticia, Grunenberg, Alexander, Döhner, Konstanze, Döhner, Hartmut, Bullinger, Lars, Haferlach, Torsten, Buske, Christian, Rawat, Vijay P S, Feuring-Buske, Michaela

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The ParaHox gene Cdx4 induces acute erythroid leukemia in mice von Thoene, Silvia, Mandal, Tamoghna, Vegi, Naidu M., Quintanilla-Martinez, Leticia, Rösler, Reinhild, Wiese, Sebastian, Metzeler, Klaus H., Herold, Tobias, Haferlach, Torsten, Döhner, Konstanze, Döhner, Hartmut, Schwarzmüller, Luisa, Klingmüller, Ursula, Buske, Christian, Rawat, Vijay P.S., Feuring-Buske, Michaela

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