Dysregulation of a family of short noncoding RNAs, tsRNAs, in human cancer von Pekarsky, Yuri, Balatti, Veronica, Palamarchuk, Alexey, Rizzotto, Lara, Veneziano, Dario, Nigita, Giovanni, Rassenti, Laura Z., Pass, Harvey I., Kipps, Thomas J., Liu, Chang-gong, Croce, Carlo M.

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A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation von Lazarian, Gregory, Yin, Shanye, ten Hacken, Elisa, Sewastianik, Tomasz, Uduman, Mohamed, Font-Tello, Alba, Gohil, Satyen H., Li, Shuqiang, Kim, Ekaterina, Joyal, Heather, Billington, Leah, Witten, Elizabeth, Zheng, Mei, Huang, Teddy, Severgnini, Mariano, Lefebvre, Valerie, Rassenti, Laura Z., Gutierrez, Catherine, Georgopoulos, Katia, Ott, Christopher J., Wang, Lili, Kipps, Thomas J., Burger, Jan A., Livak, Kenneth J., Neuberg, Donna S., Baran-Marszak, Fanny, Cymbalista, Florence, Carrasco, Ruben D., Wu, Catherine J.

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Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome von Parry, Erin M., Leshchiner, Ignaty, Guièze, Romain, Johnson, Connor, Tausch, Eugen, Parikh, Sameer A., Lemvigh, Camilla, Broséus, Julien, Hergalant, Sébastien, Messer, Conor, Utro, Filippo, Levovitz, Chaya, Rhrissorrakrai, Kahn, Li, Liang, Rosebrock, Daniel, Yin, Shanye, Deng, Stephanie, Slowik, Kara, Jacobs, Raquel, Huang, Teddy, Li, Shuqiang, Fell, Geoff, Redd, Robert, Lin, Ziao, Knisbacher, Binyamin A., Livitz, Dimitri, Schneider, Christof, Ruthen, Neil, Elagina, Liudmila, Taylor-Weiner, Amaro, Persaud, Bria, Martinez, Aina, Fernandes, Stacey M., Purroy, Noelia, Anandappa, Annabelle J., Ma, Jialin, Hess, Julian, Rassenti, Laura Z., Kipps, Thomas J., Jain, Nitin, Wierda, William, Cymbalista, Florence, Feugier, Pierre, Kay, Neil E., Livak, Kenneth J., Danysh, Brian P., Stewart, Chip, Neuberg, Donna, Davids, Matthew S., Brown, Jennifer R., Parida, Laxmi, Stilgenbauer, Stephan, Getz, Gad, Wu, Catherine J.

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Dysregulation of different classes of tRNA fragments in chronic lymphocytic leukemia von Veneziano, Dario, Tomasello, Luisa, Balatti, Veronica, Palamarchuk, Alexey, Rassenti, Laura Z., Kipps, Thomas J., Pekarsky, Yuri, Croce, Carlo M.

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miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1 von Mraz, Marek, Chen, Liguang, Rassenti, Laura Z., Ghia, Emanuela M., Li, Hongying, Jepsen, Kristen, Smith, Erin N., Messer, Karen, Frazer, Kelly A., Kipps, Thomas J.

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Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia von Wang, Lili, Brooks, Angela N., Fan, Jean, Wan, Youzhong, Gambe, Rutendo, Li, Shuqiang, Hergert, Sarah, Yin, Shanye, Freeman, Samuel S., Levin, Joshua Z., Fan, Lin, Seiler, Michael, Buonamici, Silvia, Smith, Peter G., Chau, Kevin F., Cibulskis, Carrie L., Zhang, Wandi, Rassenti, Laura Z., Ghia, Emanuela M., Kipps, Thomas J., Fernandes, Stacey, Bloch, Donald B., Kotliar, Dylan, Landau, Dan A., Shukla, Sachet A., Aster, Jon C., Reed, Robin, DeLuca, David S., Brown, Jennifer R., Neuberg, Donna, Getz, Gad, Livak, Kenneth J., Meyerson, Matthew M., Kharchenko, Peter V., Wu, Catherine J.

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cyCombine allows for robust integration of single-cell cytometry datasets within and across technologies von Pedersen, Christina Bligaard, Dam, Søren Helweg, Barnkob, Mike Bogetofte, Leipold, Michael D., Purroy, Noelia, Rassenti, Laura Z., Kipps, Thomas J., Nguyen, Jennifer, Lederer, James Arthur, Gohil, Satyen Harish, Wu, Catherine J., Olsen, Lars Rønn

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Targeting ROR1 Inhibits Epithelial―Mesenchymal Transition and Metastasis von BING CUI, SUPING ZHANG, LIGUANG CHEN, JIANQIANG YU, WIDHOPF, George F, FECTEAU, Jessie-F, RASSENTI, Laura Z, KIPPS, Thomas J

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NOTCH1 mutations in CLL associated with trisomy 12 von Balatti, Veronica, Bottoni, Arianna, Palamarchuk, Alexey, Alder, Hansjuerg, Rassenti, Laura Z., Kipps, Thomas J., Pekarsky, Yuri, Croce, Carlo M.

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Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report From the International Microarray Innovations in Leukemia... von HAFERLACH, Torsten, KOHLMANN, Alexander, GILKES, Amanda, CHIARETTI, Sabina, SHURTLEFF, Sheila A, KIPPS, Thomas J, RASSENTI, Laura Z, YEOH, Allen E, PAPENHAUSEN, Peter R, LIU, Wei-Min, WILLIAMS, P. Mickey, FOA, Robin, WIECZOREK, Lothar, BASSO, Giuseppe, TE KRONNIE, Geertruy, BONO, Marie-Christine, DE VOS, John, HERNINDEZ, Jesus M, HOFMANN, Wolf-Karsten, MILLS, Ken I

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Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia von Choi, Michael Y., Widhopf, George F., Ghia, Emanuela M., Kidwell, Reilly L., Hasan, Md Kamrul, Yu, Jian, Rassenti, Laura Z., Chen, Liguang, Chen, Yun, Pittman, Emily, Pu, Minya, Messer, Karen, Prussak, Charles E., Castro, Januario E., Jamieson, Catriona, Kipps, Thomas J.

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NF-κB-p62-NRF2 survival signaling is associated with high ROR1 expression in chronic lymphocytic leukemia von Sanchez-Lopez, Elsa, Ghia, Emanuela M., Antonucci, Laura, Sharma, Natasha, Rassenti, Laura Z., Xu, Jinyi, Sun, Beicheng, Kipps, Thomas J., Karin, Michael

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miR-125a and miR-34a expression predicts Richter syndrome in chronic lymphocytic leukemia patients von Balatti, Veronica, Tomasello, Luisa, Rassenti, Laura Z., Veneziano, Dario, Nigita, Giovanni, Wang, Huan-You, Thorson, John A., Kipps, Thomas J., Pekarsky, Yuri, Croce, Carlo M.

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Idelalisib given front-line for treatment of chronic lymphocytic leukemia causes frequent immune-mediated hepatotoxicity von Lampson, Benjamin L., Kasar, Siddha N., Matos, Tiago R., Morgan, Elizabeth A., Rassenti, Laura, Davids, Matthew S., Fisher, David C., Freedman, Arnold S., Jacobson, Caron A., Armand, Philippe, Abramson, Jeremy S., Arnason, Jon E., Kipps, Thomas J., Fein, Joshua, Fernandes, Stacey, Hanna, John, Ritz, Jerome, Kim, Haesook T., Brown, Jennifer R.

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A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion von Yin, Shanye, Gambe, Rutendo G., Sun, Jing, Martinez, Aina Zurita, Cartun, Zachary J., Regis, Fara Faye D., Wan, Youzhong, Fan, Jean, Brooks, Angela N., Herman, Sarah E.M., ten Hacken, Elisa, Taylor-Weiner, Amaro, Rassenti, Laura Z., Ghia, Emanuela M., Kipps, Thomas J., Obeng, Esther A., Cibulskis, Carrie L., Neuberg, Donna, Campagna, Dean R., Fleming, Mark D., Ebert, Benjamin L., Wiestner, Adrian, Leshchiner, Ignaty, DeCaprio, James A., Getz, Gad, Reed, Robin, Carrasco, Ruben D., Wu, Catherine J., Wang, Lili

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Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia von Biran, Anat, Yin, Shanye, Kretzmer, Helene, ten Hacken, Elisa, Parvin, Salma, Lucas, Fabienne, Uduman, Mohamed, Gutierrez, Catherine, Dangle, Nathan, Billington, Leah, Regis, Fara Faye, Rassenti, Laura Z., Mohammad, Arman, Hoffmann, Gabriela Brunsting, Stevenson, Kristen, Zheng, Mei, Witten, Elizabeth, Fernandes, Stacey M., Tausch, Eugen, Sun, Clare, Stilgenbauer, Stephan, Brown, Jennifer R., Kipps, Thomas J., Aster, John C., Gnirke, Andreas, Neuberg, Donna S., Letai, Anthony, Wang, Lili, Carrasco, Ruben D., Meissner, Alexander, Wu, Catherine J.

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Molecular map of chronic lymphocytic leukemia and its impact on outcome von Knisbacher, Binyamin A., Lin, Ziao, Hahn, Cynthia K., Nadeu, Ferran, Duran-Ferrer, Martí, Stevenson, Kristen E., Tausch, Eugen, Delgado, Julio, Barbera-Mourelle, Alex, Taylor-Weiner, Amaro, Bousquets-Muñoz, Pablo, Diaz-Navarro, Ander, Dunford, Andrew, Anand, Shankara, Kretzmer, Helene, Gutierrez-Abril, Jesus, López-Tamargo, Sara, Fernandes, Stacey M., Sun, Clare, Sivina, Mariela, Rassenti, Laura Z., Schneider, Christof, Li, Shuqiang, Parida, Laxmi, Meissner, Alexander, Aguet, François, Burger, Jan A., Wiestner, Adrian, Kipps, Thomas J., Brown, Jennifer R., Hallek, Michael, Stewart, Chip, Neuberg, Donna S., Martín-Subero, José I., Puente, Xose S., Stilgenbauer, Stephan, Wu, Catherine J., Campo, Elias, Getz, Gad

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Wnt5a enhances proliferation of chronic lymphocytic leukemia and ERK1/2 phosphorylation via a ROR1/DOCK2-dependent mechanism von Hasan, Md Kamrul, Ghia, Emanuela M., Rassenti, Laura Z., Widhopf, George F., Kipps, Thomas J.

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DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia von Oakes, Christopher C, Seifert, Marc, Assenov, Yassen, Gu, Lei, Przekopowitz, Martina, Ruppert, Amy S, Wang, Qi, Imbusch, Charles D, Serva, Andrius, Koser, Sandra D, Brocks, David, Lipka, Daniel B, Bogatyrova, Olga, Weichenhan, Dieter, Brors, Benedikt, Rassenti, Laura, Kipps, Thomas J, Mertens, Daniel, Zapatka, Marc, Lichter, Peter, Döhner, Hartmut, Küppers, Ralf, Zenz, Thorsten, Stilgenbauer, Stephan, Byrd, John C, Plass, Christoph

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MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia von Cui, Bing, Chen, Liguang, Zhang, Suping, Mraz, Marek, Fecteau, Jessie-F., Yu, Jian, Ghia, Emanuela M., Zhang, Ling, Bao, Lei, Rassenti, Laura Z., Messer, Karen, Calin, George A., Croce, Carlo M., Kipps, Thomas J.

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