Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi von Nicholson, Donald W, Gervais, François G, Singaraja, Roshni, Xanthoudakis, Steven, Gutekunst, Claire-Anne, Leavitt, Blair R, Metzler, Martina, Hackam, Abigail S, Tam, John, Vaillancourt, John P, Houtzager, Vicky, Rasper, Dita M, Roy, Sophie, Hayden, Michael R

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Purification and catalytic properties of human caspase family members von Garcia-Calvo, M, Peterson, E P, Rasper, D M, Vaillancourt, J P, Zamboni, R, Nicholson, D W, Thornberry, N A

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The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis von Rotonda, Jennifer, Nicholson, Donald W, Fazil, Kimberly M, Gallant, Michel, Gareau, Yves, Labelle, Marc, Peterson, Erin P, Rasper, Dita M, Ruel, Réjean, Vaillancourt, John P, Thornberry, Nancy A, Becker, Joseph W

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A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B von Thornberry, Nancy A., Rano, Thomas A., Peterson, Erin P., Rasper, Dita M., Timkey, Tracy, Garcia-Calvo, Margarita, Houtzager, Vicky M., Nordstrom, Penny A., Roy, Sophie, Vaillancourt, John P., Chapman, Kevin T., Nicholson, Donald W.

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Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex von Rasper, D M, Vaillancourt, J P, Hadano, S, Houtzager, V M, Seiden, I, Keen, S L, Tawa, P, Xanthoudakis, S, Nasir, J, Martindale, D, Koop, B F, Peterson, E P, Thornberry, N A, Huang, J, MacPherson, D P, Black, S C, Hornung, F, Lenardo, M J, Hayden, M R, Roy, S, Nicholson, D W

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis von Thornberry, N A, Rano, T A, Peterson, E P, Rasper, D M, Timkey, T, Garcia-Calvo, M, Houtzager, V M, Nordstrom, P A, Roy, S, Vaillancourt, J P, Chapman, K T, Nicholson, D W

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Novel pyrazinone mono-amides as potent and reversible caspase-3 inhibitors von Han, Yongxin, Giroux, André, Colucci, John, Bayly, Christopher I., Mckay, Daniel J., Roy, Sophie, Xanthoudakis, Steve, Vaillancourt, John, Rasper, Dita M., Tam, John, Tawa, Paul, Nicholson, Donald W., Zamboni, Robert J.

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Discovery of novel aspartyl ketone dipeptides as potent and selective caspase-3 inhibitors von Han, Yongxin, Giroux, André, Grimm, Erich L., Aspiotis, Renée, Francoeur, Sébastien, Bayly, Christopher I., Mckay, Daniel J., Roy, Sophie, Xanthoudakis, Steve, Vaillancourt, John P., Rasper, Dita M., Tam, John, Tawa, Paul, Thornberry, Nancy A., Paterson, Erin P., Garcia-Calvo, Margarita, Becker, Joseph W., Rotonda, Jennifer, Nicholson, Donald W., Zamboni, Robert J.

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Solid-phase analogue synthesis of caspase-3 inhibitors via palladium-catalyzed amination of 3-bromopyrazinones von Isabel, Elise, Aspiotis, Renee, Black, W. Cameron, Colucci, John, Fortin, Réjean, Giroux, André, Grimm, Erich L., Han, Yongxin, Mellon, Christophe, Nicholson, Donald W., Rasper, Dita M., Renaud, Johanne, Roy, Sophie, Tam, John, Tawa, Paul, Vaillancourt, John P., Xanthoudakis, Steven, Zamboni, Robert J.

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Nicotinyl aspartyl ketones as inhibitors of caspase-3 von Isabel, Elise, Black, W.Cameron, Bayly, Christopher I, Grimm, Erich L, Janes, Marc K, McKay, Daniel J, Nicholson, Donald W, Rasper, Dita M, Renaud, Johanne, Roy, Sophie, Tam, John, Thornberry, Nancy A, Vaillancourt, John P, Xanthoudakis, Steven, Zamboni, Robert

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Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors von MELLON, Christophe, ASPIOTIS, Reneé, RASPER, Dita M, ROY, Sophie, TAM, John, THORNBERRY, Nancy A, VAILLANCOURT, John P, XANTHOUDAKIS, Steven, ZAMBONI, Robert, BLACK, Cameron W, BAYLY, Christopher I, GRIMM, Erich L, GIROUX, André, YONGXIN HAN, ISABEL, Elise, MCKAY, Daniel J, NICHOLSON, Donald W

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Solid phase synthesis of selective caspase-3 peptide inhibitors von GRIMM, Erich L, ROY, Bruno, VAILLANCOURT, John P, XANTHOUDAKIS, Steven, ZAMBONI, Robert J, ASPIOTIS, Renee, BAYLY, Christopher I, NICHOLSON, Donald W, RASPER, Dita M, RENAUD, Johanne, ROY, Sophie, TAM, John, TAWA, Paul

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HIP12 is a non-proapoptotic member of a gene family including HIP1, an interacting protein with huntingtin von Chopra, V S, Metzler, M, Rasper, D M, Engqvist-Goldstein, A E, Singaraja, R, Gan, L, Fichter, K M, McCutcheon, K, Drubin, D, Nicholson, D W, Hayden, M R

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Evidence for the modulation of Pseudomonas aeruginosa Exotoxin A-Induced Pore Formation by Membrane Surface Charge Density von Rasper, Dita M, Merrill, A. Rod

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Lipophilic versus hydrogen-bonding effect in P 3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors von Mellon, Christophe, Aspiotis, Reneé, Black, Cameron W., Bayly, Christopher I., Grimm, Erich L., Giroux, André, Han, Yongxin, Isabel, Elise, McKay, Daniel J., Nicholson, Donald W., Rasper, Dita M., Roy, Sophie, Tam, John, Thornberry, Nancy A., Vaillancourt, John P., Xanthoudakis, Steven, Zamboni, Robert

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Genomic organization of the human caspase-9 gene on Chromosome 1p36.1-p36.3 von Hadano , † , Jamal Nasir, Shinji, Nichol, Kerrie, Rasper, Dita M., Vaillancourt, John P., Sherer, Stephen W., Beatty, Barbara G., Ikeda †, †† , Donald, Joh-E, Hayden, Michael R.

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Purification of human leukotriene C4 synthase from dimethylsulfoxide‐differentiated U937 cells von NICHOLSON, Donald W., KLEMBA, Michael W., RASPER, Dita M., METTERS, Kathleen M., ZAMBONI, Robert J., FORD‐HUTCHINSON, Anthony W.

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Purification of human leukotriene C 4 synthase from dimethylsulfoxide‐differentiated U937 cells von NICHOLSON, Donald W., KLEMBA, Michael W., RASPER, Dita M., METTERS, Kathleen M., ZAMBONI, Robert J., FORD‐HUTCHINSON, Anthony W.

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USURPIN, A MAMMALIAN DED-CASPASE HOMOLOGUE THAT PRECLUDES CASPASE-8 RECRUITMENT AND ACTIVATION BY THE CD-95 (FAS, APO-1) RECEPTOR COMPLEX von RASPER, DITA, M, XANTHOUDAKIS, STEVE, NICHOLSON, DONALD, W, ROY, SOPHIE

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USURPIN, A MAMMALIAN DED-CASPASE HOMOLOGUE THAT PRECLUDES CASPASE-8 RECRUITMENT AND ACTIVATION BY THE CD-95 (FAS, APO-1) RECEPTOR COMPLEX von RASPER, DITA, M, XANTHOUDAKIS, STEVE, NICHOLSON, DONALD, W, ROY, SOPHIE

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