From strain engineering to process development: monoclonal antibody production with an unnatural amino acid in Pichia pastoris von Tir, Nora, Heistinger, Lina, Grünwald-Gruber, Clemens, Jakob, Leo A, Dickgiesser, Stephan, Rasche, Nicolas, Mattanovich, Diethard

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Engineering hydrophobicity and manufacturability for optimized biparatopic antibody-drug conjugates targeting c-MET von Evers, Andreas, Krah, Simon, Demir, Deniz, Gaa, Ramona, Elter, Desislava, Schroeter, Christian, Zielonka, Stefan, Rasche, Nicolas, Dotterweich, Julia, Knuehl, Christine, Doerner, Achim

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Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein von Schmitzová, Jana, Rasche, Nicolas, Dybkov, Olexander, Kramer, Katharina, Fabrizio, Patrizia, Urlaub, Henning, Lührmann, Reinhard, Pena, Vladimir

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Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug Conjugates von Sellmann, Carolin, Doerner, Achim, Knuehl, Christine, Rasche, Nicolas, Sood, Vanita, Krah, Simon, Rhiel, Laura, Messemer, Annika, Wesolowski, John, Schuette, Mark, Becker, Stefan, Toleikis, Lars, Kolmar, Harald, Hock, Bjoern

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Site-Specific Antibody–Drug Conjugation Using Microbial Transglutaminase von Dickgiesser, Stephan, Deweid, Lukas, Kellner, Roland, Kolmar, Harald, Rasche, Nicolas

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Generation and Biological Evaluation of Fc Antigen Binding Fragment-Drug Conjugates as a Novel Antibody-Based Format for Targeted Drug Delivery von Jäger, Sebastian, Wagner, Tim R, Rasche, Nicolas, Kolmar, Harald, Hecht, Stefan, Schröter, Christian

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Sortagged anti-EGFR immunoliposomes exhibit increased cytotoxicity on target cells von Wöll, Steffen, Dickgiesser, Stephan, Rasche, Nicolas, Schiller, Stefan, Scherließ, Regina

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Site-Specific Conjugation of Thiol-Reactive Cytotoxic Agents to Nonnative Cysteines of Engineered Monoclonal Antibodies von Dickgiesser, Stephan, Kellner, Roland, Kolmar, Harald, Rasche, Nicolas

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Effect of Conjugation Site and Technique on the Stability and Pharmacokinetics of Antibody-Drug Conjugates von Kaempffe, Anna, Dickgiesser, Stephan, Rasche, Nicolas, Paoletti, Andrea, Bertotti, Elisa, De Salve, Ilse, Sirtori, Federico Riccardi, Kellner, Roland, Könning, Doreen, Hecht, Stefan, Anderl, Jan, Kolmar, Harald, Schröter, Christian

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Site-Specific Conjugation of Native Antibodies Using Engineered Microbial Transglutaminases von Dickgiesser, Stephan, Rieker, Marcel, Mueller-Pompalla, Dirk, Schröter, Christian, Tonillo, Jason, Warszawski, Shira, Raab-Westphal, Sabine, Kühn, Stefanie, Knehans, Tim, Könning, Doreen, Dotterweich, Julia, Betz, Ulrich A. K, Anderl, Jan, Hecht, Stefan, Rasche, Nicolas

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Generation and Characterization of Iduronidase-Cleavable ADCs von Jäger, Sebastian, Könning, Doreen, Rasche, Nicolas, Hart, Felix, Sensbach, Janike, Krug, Carina, Raab-Westphal, Sabine, Richter, Konstantin, Unverzagt, Carlo, Hecht, Stefan, Anderl, Jan, Schröter, Christian

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Welding PROxAb Shuttles: A Modular Approach for Generating Bispecific Antibodies via Site-Specific Protein–Protein Conjugation von Lehmann, Tanja, Schneider, Hendrik, Tonillo, Jason, Schanz, Jennifer, Schwarz, Daniel, Schröter, Christian, Jäger, Sebastian, Kolmar, Harald, Hecht, Stefan, Anderl, Jan, Rasche, Nicolas, Rieker, Marcel, Dickgiesser, Stephan

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Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre von Rasche, Nicolas, Dybkov, Olexandr, Schmitzová, Jana, Akyildiz, Berktan, Fabrizio, Patrizia, Lührmann, Reinhard

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A Chemoenzymatic Approach to Protein Immobilization onto Crystalline Cellulose Nanoscaffolds von Uth, Christina, Zielonka, Stefan, Hörner, Sebastian, Rasche, Nicolas, Plog, Andreas, Orelma, Hannes, Avrutina, Olga, Zhang, Kai, Kolmar, Harald

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Efficient spontaneous site-selective cysteine-mediated toxin attachment within a structural loop of antibodies von Stadlmayr, Gerhard, Stracke, Florian, Stadlbauer, Katharina, Rybka, Jakub, Dickgiesser, Stephan, Rasche, Nicolas, Becker, Stefan, Toleikis, Lars, Rüker, Florian, Knopp, Gordana Wozniak

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Proteome Analysis of Arabidopsis Leaf Peroxisomes Reveals Novel Targeting Peptides, Metabolic Pathways, and Defense Mechanisms von Reumann, Sigrun, Babujee, Lavanya, Ma, Changle, Wienkoop, Stephanie, Siemsen, Tanja, Antonicelli, Gerardo E., Rasche, Nicolas, Lüder, Franziska, Weckwerth, Wolfram, Jahn, Olaf

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Generation of human bispecific common light chain antibodies by combining animal immunization and yeast display von Krah, Simon, Schröter, Christian, Eller, Carla, Rhiel, Laura, Rasche, Nicolas, Beck, Jan, Sellmann, Carolin, Günther, Ralf, Toleikis, Lars, Hock, Björn, Kolmar, Harald, Becker, Stefan

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Isolation of Anti-Hapten Antibodies by Fluorescence-Activated Cell Sorting of Yeast-Displayed B-Cell Receptor Gene Repertoires von Jäger, Sebastian, Krah, Simon, Könning, Doreen, Rosskopf, Janis, Dickgiesser, Stephan, Rasche, Nicolas, Kolmar, Harald, Hecht, Stefan, Schröter, Christian

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Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS von Ohrt, Thomas, Prior, Mira, Dannenberg, Julia, Odenwälder, Peter, Dybkov, Olexandr, Rasche, Nicolas, Schmitzová, Jana, Gregor, Ingo, Fabrizio, Patrizia, Enderlein, Jörg, Lührmann, Reinhard

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Self-Assembled Hybrid Aptamer-Fc Conjugates for Targeted Delivery: A Modular Chemoenzymatic Approach von Dickgiesser, Stephan, Rasche, Nicolas, Nasu, Daichi, Middel, Stephen, Hörner, Sebastian, Avrutina, Olga, Diederichsen, Ulf, Kolmar, Harald

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