Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure von Shi, Gang, Johnson, Toby, Johnson, Andrew D, Bochud, Murielle, Rice, Kenneth M, Ehret, Georg B, Amin, Najaf, Mooser, Vincent, Dörr, Marcus, Esko, Tõnu, Pirastu, Nicola, Pichler, Irene, Jackson, Anne U, Zhang, Feng, Peden, John F, Schmidt, Helena, Tanaka, Toshiko, Igl, Wilmar, Vitart, Veronique, Chasman, Daniel I, Trompet, Stella, Bragg-Gresham, Jennifer L, Kühnel, Brigitte, Lopez, Lorna M, Polašek, Ozren, Boban, Mladen, Morrison, Alanna C, Pihur, Vasyl, Mattace-Raso, Francesco U S, Rivadeneira, Fernando, Uitterlinden, Andre G, Bergmann, Sven, Waeber, Gérard, Laitinen, Jaana, Pouta, Anneli, McArdle, Wendy L, Glazer, Nicole L, Alavere, Helene, Keis, Aime, Tammesoo, Mari-Liis, Barroso, Inês, Eyheramendy, Susana, Penninx, Brenda W, Groop, Leif, Salomaa, Veikko, d'Adamo, Adamo Pio, Fabretto, Antonella, Faletra, Flavio, Ulivi, Sheila, Collins, Francis S, Shin, So-Youn, Soranzo, Nicole, Watkins, Hugh, Hamsten, Anders, Gider, Pierre, Zeginigg, Marion, Najjar, Samer S, Wild, Sarah H, Corsi, Anna Maria, de Geus, Eco J C, Parker, Alex N, Buckley, Brendan, van der Klauw, Melanie M, Zhang, Weihua, Kähönen, Mika, Viikari, Jorma, Meitinger, Thomas, Emilsson, Valur, König, Inke R, Felix, Janine F, Hopewell, Jemma C, Breteler, Monique, Debette, Stéphanie, DeStefano, Anita L, Smith, Nicholas L, Thorleifsson, Gudmar, Preuss, Michael, Raitakari, Olli T, Stolk, Ronald P, Jukema, J Wouter, Farrall, Martin, Pfeufer, Arne, Altshuler, David, Loos, Ruth J F, Toniolo, Daniela, Gieger, Christian, Metspalu, Andres, Launer, Lenore, Strachan, David P, Beckmann, Jacques S, Witteman, Jacqueline C M, van Dijk, Ko Willems, Boehnke, Michael, Jarvelin, Marjo-Riitta, Abecasis, Goncalo R, Gudnason, Vilmundur, Levy, Daniel, Psaty, Bruce M, Rao, Dabeeru C, Tobin, Martin D

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A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk von Heinig, Matthias, Petretto, Enrico, Wallace, Chris, Bottolo, Leonardo, Rotival, Maxime, Lu, Han, Li, Yoyo, Sarwar, Rizwan, Langley, Sarah R., Bauerfeind, Anja, Hummel, Oliver, Lee, Young-Ae, Paskas, Svetlana, Rintisch, Carola, Saar, Kathrin, Cooper, Jason, Buchan, Rachel, Gray, Elizabeth E., Cyster, Jason G., Erdmann, Jeanette, Hengstenberg, Christian, Maouche, Seraya, Ouwehand, Willem H., Rice, Catherine M., Samani, Nilesh J., Schunkert, Heribert, Goodall, Alison H., Schulz, Herbert, Roider, Helge G., Vingron, Martin, Blankenberg, Stefan, Münzel, Thomas, Zeller, Tanja, Szymczak, Silke, Ziegler, Andreas, Tiret, Laurence, Smyth, Deborah J., Pravenec, Michal, Aitman, Timothy J., Cambien, Francois, Clayton, David, Todd, John A., Hubner, Norbert, Cook, Stuart A.

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A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways von Jones, Chris I., Bray, Sarah, Garner, Stephen F., Stephens, Jonathan, de Bono, Bernard, Angenent, Will G.J., Bentley, David, Burns, Philippa, Coffey, Alison, Deloukas, Panos, Earthrowl, Mark, Farndale, Richard W., Hoylaerts, Marc F., Koch, Kerstin, Rankin, Angela, Rice, Catherine M., Rogers, Jane, Samani, Nilesh J., Steward, Michael, Walker, Adam, Watkins, Nicholas A., Akkerman, Jan-Willem, Dudbridge, Frank, Goodall, Alison H., Ouwehand, Willem H.

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Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts von Floto, R Andres, Clatworthy, Menna R, Heilbronn, Karen R, Rosner, Dalya R, MacAry, Paul A, Rankin, Angela, Lehner, Paul J, Ouwehand, Willem H, Allen, Janet M, Watkins, Nicholas A, Smith, Kenneth G C

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Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation von Huang, Jie, Sabater-Lleal, Maria, Asselbergs, Folkert W., Tregouet, David, Shin, So-Youn, Ding, Jingzhong, Baumert, Jens, Oudot-Mellakh, Tiphaine, Folkersen, Lasse, Johnson, Andrew D., Smith, Nicholas L., Williams, Scott M., Ikram, Mohammad A., Kleber, Marcus E., Becker, Diane M., Truong, Vinh, Mychaleckyj, Josyf C., Tang, Weihong, Yang, Qiong, Sennblad, Bengt, Moore, Jason H., Williams, Frances M.K., Dehghan, Abbas, Silbernagel, Günther, Schrijvers, Elisabeth M.C., Smith, Shelly, Karakas, Mahir, Tofler, Geoffrey H., Silveira, Angela, Navis, Gerjan J., Lohman, Kurt, Chen, Ming-Huei, Peters, Annette, Goel, Anuj, Hopewell, Jemma C., Chambers, John C., Saleheen, Danish, Lundmark, Per, Psaty, Bruce M., Strawbridge, Rona J., Boehm, Bernhard O., Carter, Angela M., Meisinger, Christa, Peden, John F., Bis, Joshua C., McKnight, Barbara, Öhrvik, John, Taylor, Kent, Franzosi, Maria Grazia, Seedorf, Udo, Collins, Rory, Franco-Cereceda, Anders, Syvänen, Ann-Christine, Goodall, Alison H., Yanek, Lisa R., Cushman, Mary, Müller-Nurasyid, Martina, Folsom, Aaron R., Basu, Saonli, Matijevic, Nena, van Gilst, Wiek H., Kooner, Jaspal S., Hofman, Albert, Danesh, John, Clarke, Robert, Meigs, James B., Kathiresan, Sekar, Reilly, Muredach P., Klopp, Norman, Harris, Tamara B., Winkelmann, Bernhard R., Grant, Peter J., Hillege, Hans L., Watkins, Hugh, Spector, Timothy D., Becker, Lewis C., Tracy, Russell P., März, Winfried, Uitterlinden, Andre G., Eriksson, Per, Cambien, Francois, Morange, Pierre-Emmanuel, Koenig, Wolfgang, Soranzo, Nicole, van der Harst, Pim, Liu, Yongmei, O'Donnell, Christopher J., Hamsten, Anders

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A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function von Soranzo, Nicole, Rendon, Augusto, Gieger, Christian, Jones, Chris I., Watkins, Nicholas A., Menzel, Stephan, Döring, Angela, Stephens, Jonathan, Prokisch, Holger, Erber, Wendy, Potter, Simon C., Bray, Sarah L., Burns, Philippa, Jolley, Jennifer, Falchi, Mario, Kühnel, Brigitte, Erdmann, Jeanette, Schunkert, Heribert, Samani, Nilesh J., Illig, Thomas, Garner, Stephen F., Rankin, Angela, Meisinger, Christa, Bradley, John R., Thein, Swee Lay, Goodall, Alison H., Spector, Tim D., Deloukas, Panos, Ouwehand, Willem H.

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Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene von Davison, Lucy J., Wallace, Chris, Cooper, Jason D., Cope, Nathan F., Wilson, Nicola K., Smyth, Deborah J., Howson, Joanna M.M., Saleh, Nada, Al-Jeffery, Abdullah, Angus, Karen L., Stevens, Helen E., Nutland, Sarah, Duley, Simon, Coulson, Richard M.R., Walker, Neil M., Burren, Oliver S., Rice, Catherine M., Cambien, Francois, Zeller, Tanja, Munzel, Thomas, Lackner, Karl, Blankenberg, Stefan, Fraser, Peter, Gottgens, Berthold, Todd, John A.

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Genome-wide haplotype analysis of cis expression quantitative trait loci in monocytes von Garnier, Sophie, Truong, Vinh, Brocheton, Jessy, Zeller, Tanja, Rovital, Maxime, Wild, Philipp S, Ziegler, Andreas, Munzel, Thomas, Tiret, Laurence, Blankenberg, Stefan, Deloukas, Panos, Erdmann, Jeannette, Hengstenberg, Christian, Samani, Nilesh J, Schunkert, Heribert, Ouwehand, Willem H, Goodall, Alison H, Cambien, François, Trégouët, David-Alexandre

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A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential von Rocanin-Arjo, Ares, Cohen, William, Carcaillon, Laure, Frère, Corinne, Saut, Noémie, Letenneur, Luc, Alhenc-Gelas, Martine, Dupuy, Anne-Marie, Bertrand, Marion, Alessi, Marie-Christine, Germain, Marine, Wild, Philipp S., Zeller, Tanja, Cambien, Francois, Goodall, Alison H., Amouyel, Philippe, Scarabin, Pierre-Yves, Trégouët, David-Alexandre, Morange, Pierre-Emmanuel

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PECAM-1 expression and activity negatively regulate multiple platelet signaling pathways von Jones, Chris I., Garner, Stephen F., Moraes, Leonardo A., Kaiser, William J., Rankin, Angela, Ouwehand, Willem H., Goodall, Alison H., Gibbins, Jonathan M.

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The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression von Joutsi-Korhonen, Lotta, Smethurst, Peter A., Rankin, Angela, Gray, Elaine, IJsseldijk, Martin, Onley, Catherine M., Watkins, Nicholas A., Williamson, Lorna M., Goodall, Alison H., de Groot, Philip G., Farndale, Richard W., Ouwehand, Willem H.

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Alloantibodies against low-frequency human platelet antigens do not account for a significant proportion of cases of fetomaternal alloimmune thrombocytopenia: evidence from 1054 ca... von Ghevaert, Cedric, Rankin, Angela, Huiskes, Elly, Porcelijn, Leendert, Javela, Kaija, Kekomaki, Riitta, Bakchoul, Tamam, Santoso, Sentot, Nutland, Sarah, Smyth, Deborah J., Smith, Graham A., McBride, Simon, Watkins, Nicholas A., Ouwehand, Willem H.

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Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes von Almlöf, Jonas Carlsson, Lundmark, Per, Lundmark, Anders, Ge, Bing, Pastinen, Tomi, Goodall, Alison H, Cambien, François, Deloukas, Panos, Ouwehand, Willem H, Syvänen, Ann-Christine

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A single-nucleotide polymorphism in the human ITGB3 gene is associated with the platelet-specific alloantigen Vaa (HPA-17bw) involved in fetal maternal alloimmune thrombocytopenia von Stafford, Prachi, Garner, Stephen F., Rankin, Angela, Kekomaki, Riitta, Watkins, Nicholas A., Ouwehand, Willem H.

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Comprehensive exploration of the effects of miRNA SNPs on monocyte gene expression von Greliche, Nicolas, Zeller, Tanja, Wild, Philipp S, Rotival, Maxime, Schillert, Arne, Ziegler, Andreas, Deloukas, Panos, Erdmann, Jeanette, Hengstenberg, Christian, Ouwehand, Willem H, Samani, Nilesh J, Schunkert, Heribert, Munzel, Thomas, Lackner, Karl J, Cambien, François, Goodall, Alison H, Tiret, Laurence, Blankenberg, Stefan, Trégouët, David-Alexandre

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A single-nucleotide polymorphism in the human ITGB3 gene is associated with the platelet-specific alloantigen Va (HPA-17bw) involved in fetal maternal alloimmune thrombocytopenia von Stafford, Prachi, Garner, Stephen F, Rankin, Angela, Kekomaki, Riitta, Watkins, Nicholas A, Ouwehand, Willem H

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Correction: Comprehensive Exploration of the Effects of miRNA SNPs on Monocyte Gene Expression von Greliche, Nicolas, Zeller, Tanja, Wild, Philipp S., Rotival, Maxime, Schillert, Arne, Ziegler, Andreas, Attwood, Tony, Stephanie, Belz, Braund, Peter, Brocheton, Jessy, Cooper, Jason, Crisp-Hihn, Abi, Diemert, Patrick (formerly Linsel-Nitschke), Foad, Nicola, Godefroy, Tiphaine, Gracey, Jay, Gray, Emma, Gwilliams, Rhian, Heimerl, Susanne, Jolley, Jennifer, Krishnan, Unni, Lloyd-Jones, Heather, Liljedahl, Ulrika, Lugauer, Ingrid, Lundmark, Per, Maouche, Seraya, Moore, Jasbir S, Gilles, Montalescot, Muir, David, Murray, Elizabeth, Nelson, Chris P, Neudert, Jessica, Niblett, David, O.Leary, Karen, Pollard, Helen, Proust, Carole, Rankin, Angela, Rendon, Augusto, Rice, Catherine M, Sager, Hendrik, Sambrook, Jennifer, Gerd, Schmitz, Scholz, Michael, Schroeder, Laura, Stephens, Jonathan, Syvannen, Ann-Christine, Tennstedt, Stefanie (formerlyGulde), Wallace, Chris

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A naturally occurring Leu33Val mutation in β3-integrin impairs the HPA-1a epitope: the third allele of HPA-1 von Santoso, Sentot, Kroll, Hartmut, Andrei-Selmer, Cornelia L., Socher, Ines, Rankin, Angela, Kretzschmar, Evelyne, Watkins, Nicholas A., Ouwehand, Willem H.

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A Common Single Nucleotide Polymorphism in the Chromosome 7q22.3 Region, Which Is Frequently Deleted in Myeloid Malignancies, Is Associated with Mean Platelet Volume and Platelet F... von Soranzo, Nicole, Tijssen, Marloes R., Rendon, Augusto, Meisinger, Christine, Jones, Chris I., Gieger, Christian, Watkins, Nicholas A., Menzel, Stephan, Prokisch, Holger, Stephens, Jonathan, Doering, Angela, Erber, Wendy N., Potter, Simon C., Burns, Philippa, Jolley, Jennifer, Falchi, Mario, Garner, Stephen F., Rankin, Angela, Thein, Swee Lay, Wichmann, H-Erich, Goodall, Alison H., Illig, Thomas, Spector, Tim D., Deloukas, Panos, Ouwehand, Willem H.

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A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the αIIbβ3 integrin and cosegregates dominantly with abnormal proplatelet... von Ghevaert, Cedric, Salsmann, Alexandre, Watkins, Nicholas A., Schaffner-Reckinger, Elisabeth, Rankin, Angela, Garner, Stephen F., Stephens, Jonathan, Smith, Graham A., Debili, Najet, Vainchenker, William, de Groot, Philip G., Huntington, James A., Laffan, Mike, Kieffer, Nelly, Ouwehand, Willem H.

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