Mechanisms of Cancer Cell Dormancy--Another Hallmark of Cancer? von Yeh, Albert C, Ramaswamy, Sridhar

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MYC and Metastasis von WOLFER, Anita, RAMASWAMY, Sridhar

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Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models von Wang, Zebin, Sun, Kaiming, Xiao, Yonghong, Feng, Bin, Mikule, Keith, Ma, XiaoYan, Feng, Ningping, Vellano, Christopher P., Federico, Lorenzo, Marszalek, Joseph R., Mills, Gordon B., Hanke, Jeffrey, Ramaswamy, Sridhar, Wang, Jing

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Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism von Perera, Rushika M., Stoykova, Svetlana, Nicolay, Brandon N., Ross, Kenneth N., Fitamant, Julien, Boukhali, Myriam, Lengrand, Justine, Deshpande, Vikram, Selig, Martin K., Ferrone, Cristina R., Settleman, Jeff, Stephanopoulos, Gregory, Dyson, Nicholas J., Zoncu, Roberto, Ramaswamy, Sridhar, Haas, Wilhelm, Bardeesy, Nabeel

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Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells von Yang, Wanjuan, Soares, Jorge, Greninger, Patricia, Edelman, Elena J, Lightfoot, Howard, Forbes, Simon, Bindal, Nidhi, Beare, Dave, Smith, James A, Thompson, I Richard, Ramaswamy, Sridhar, Futreal, P Andrew, Haber, Daniel A, Stratton, Michael R, Benes, Cyril, McDermott, Ultan, Garnett, Mathew J

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Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis von Aceto, Nicola, Bardia, Aditya, Miyamoto, David T., Donaldson, Maria C., Wittner, Ben S., Spencer, Joel A., Yu, Min, Pely, Adam, Engstrom, Amanda, Zhu, Huili, Brannigan, Brian W., Kapur, Ravi, Stott, Shannon L., Shioda, Toshi, Ramaswamy, Sridhar, Ting, David T., Lin, Charles P., Toner, Mehmet, Haber, Daniel A., Maheswaran, Shyamala

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ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells von Yazinski, Stephanie A, Comaills, Valentine, Buisson, Rémi, Genois, Marie-Michelle, Nguyen, Hai Dang, Ho, Chu Kwen, Todorova Kwan, Tanya, Morris, Robert, Lauffer, Sam, Nussenzweig, André, Ramaswamy, Sridhar, Benes, Cyril H, Haber, Daniel A, Maheswaran, Shyamala, Birrer, Michael J, Zou, Lee

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RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance von Miyamoto, David T., Zheng, Yu, Wittner, Ben S., Lee, Richard J., Zhu, Huili, Broderick, Katherine T., Desai, Rushil, Fox, Douglas B., Brannigan, Brian W., Trautwein, Julie, Arora, Kshitij S., Desai, Niyati, Dahl, Douglas M., Sequist, Lecia V., Smith, Matthew R., Kapur, Ravi, Wu, Chin-Lee, Shioda, Toshi, Ramaswamy, Sridhar, Ting, David T., Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.

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Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility von Yu, Min, Bardia, Aditya, Aceto, Nicola, Bersani, Francesca, Madden, Marissa W., Donaldson, Maria C., Desai, Rushil, Zhu, Huili, Comaills, Valentine, Zheng, Zongli, Wittner, Ben S., Stojanov, Petar, Brachtel, Elena, Sgroi, Dennis, Kapur, Ravi, Shioda, Toshihiro, Ting, David T., Ramaswamy, Sridhar, Getz, Gad, Iafrate, A. John, Benes, Cyril, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.

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Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition von Yu, Min, Bardia, Aditya, Wittner, Ben S., Stott, Shannon L, Smas, Malgorzata E., Ting, David T., Isakoff, Steven J., Ciciliano, Jordan C., Wells, Marissa N., Shah, Ajay M., Concannon, Kyle F., Donaldson, Maria C., Sequist, Lecia V., Brachtel, Elena, Sgroi, Dennis, Baselga, Jose, Ramaswamy, Sridhar, Toner, Mehmet, Haber, Daniel A., Maheswaran, Shyamala

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Statistical assessment and visualization of synergies for large-scale sparse drug combination datasets von Amzallag, Arnaud, Ramaswamy, Sridhar, Benes, Cyril H

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Customer Perception Analysis Using Deep Learning and NLP von Ramaswamy, Sridhar, DeClerck, Natalie

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Patient-derived models of acquired resistance can identify effective drug combinations for cancer von Crystal, Adam S., Shaw, Alice T., Sequist, Lecia V., Friboulet, Luc, Niederst, Matthew J., Lockerman, Elizabeth L., Frias, Rosa L., Gainor, Justin F., Amzallag, Arnaud, Greninger, Patricia, Lee, Dana, Kalsy, Anuj, Gomez-Caraballo, Maria, Elamine, Leila, Howe, Emily, Hur, Wooyoung, Lifshits, Eugene, Robinson, Hayley E., Katayama, Ryohei, Faber, Anthony C., Awad, Mark M., Ramaswamy, Sridhar, Mino-Kenudson, Mari, Iafrate, A. John, Benes, Cyril H., Engelman, Jeffrey A.

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A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations von Sharma, Sreenath V., Lee, Diana Y., Li, Bihua, Quinlan, Margaret P., Takahashi, Fumiyuki, Maheswaran, Shyamala, McDermott, Ultan, Azizian, Nancy, Zou, Lee, Fischbach, Michael A., Wong, Kwok-Kin, Brandstetter, Kathleyn, Wittner, Ben, Ramaswamy, Sridhar, Classon, Marie, Settleman, Jeff

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A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models von Sun, Kaiming, Mikule, Keith, Wang, Zebin, Poon, Grace, Vaidyanathan, Aparajitha, Smith, Gillian, Zhang, Zhi-Yi, Hanke, Jeffrey, Ramaswamy, Sridhar, Wang, Jing

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The IGF2 intronic miR-483 selectively enhances transcription from IGF2 fetal promoters and enhances tumorigenesis von Liu, Mingzhu, Roth, Anna, Yu, Min, Morris, Robert, Bersani, Francesca, Rivera, Miguel N, Lu, Jun, Shioda, Toshihiro, Vasudevan, Shobha, Ramaswamy, Sridhar, Maheswaran, Shyamala, Diederichs, Sven, Haber, Daniel A

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Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer von Bersani, Francesca, Lee, Eunjung, Kharchenko, Peter V., Xu, Andrew W., Liu, Mingzhu, Xega, Kristina, MacKenzie, Olivia C., Brannigan, Brian W., Wittner, Ben S., Jung, Hyunchul, Ramaswamy, Sridhar, Park, Peter J., Maheswaran, Shyamala, Ting, David T., Haber, Daniel A.

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Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy von Hong, Xin, Sullivan, Ryan J., Kalinich, Mark, Kwan, Tanya Todorova, Giobbie-Hurder, Anita, Pan, Shiwei, LiCausi, Joseph A., Milner, John D., Nieman, Linda T., Wittner, Ben S., Ho, Uyen, Chen, Tianqi, Kapur, Ravi, Lawrence, Donald P., Flaherty, Keith T., Sequist, Lecia V., Ramaswamy, Sridhar, Miyamoto, David T., Lawrence, Michael, Toner, Mehmet, Isselbacher, Kurt J., Maheswaran, Shyamala, Haber, Daniel A.

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REDD1 loss reprograms lipid metabolism to drive progression of RAS mutant tumors von Qiao, Shuxi, Koh, Siang-Boon, Vivekanandan, Varunika, Salunke, Devika, Patra, Krushna Chandra, Zaganjor, Elma, Ross, Kenneth, Mizukami, Yusuke, Jeanfavre, Sarah, Chen, Athena, Mino-Kenudson, Mari, Ramaswamy, Sridhar, Clish, Clary, Haigis, Marcia, Bardeesy, Nabeel, Ellisen, Leif W

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AR Expression in Breast Cancer CTCs Associates with Bone Metastases von Aceto, Nicola, Bardia, Aditya, Wittner, Ben S, Donaldson, Maria C, O'Keefe, Ryan, Engstrom, Amanda, Bersani, Francesca, Zheng, Yu, Comaills, Valentine, Niederhoffer, Kira, Zhu, Huili, Mackenzie, Olivia, Shioda, Toshi, Sgroi, Dennis, Kapur, Ravi, Ting, David T, Moy, Beverly, Ramaswamy, Sridhar, Toner, Mehmet, Haber, Daniel A, Maheswaran, Shyamala

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