Deep mutational scanning and machine learning reveal structural and molecular rules governing allosteric hotspots in homologous proteins von Leander, Megan, Liu, Zhuang, Cui, Qiang, Raman, Srivatsan

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Epistasis shapes the fitness landscape of an allosteric specificity switch von Nishikawa, Kyle K., Hoppe, Nicholas, Smith, Robert, Bingman, Craig, Raman, Srivatsan

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Mapping the functional landscape of the receptor binding domain of T7 bacteriophage by deep mutational scanning von Huss, Phil, Meger, Anthony, Leander, Megan, Nishikawa, Kyle, Raman, Srivatsan

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Evolution-guided optimization of biosynthetic pathways von Raman, Srivatsan, Rogers, Jameson K., Taylor, Noah D., Church, George M.

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A parameterized two-domain thermodynamic model explains diverse mutational effects on protein allostery von Liu, Zhuang, Gillis, Thomas G, Raman, Srivatsan, Cui, Qiang

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Engineering an allosteric transcription factor to respond to new ligands von Taylor, Noah D, Garruss, Alexander S, Moretti, Rocco, Chan, Sum, Arbing, Mark A, Cascio, Duilio, Rogers, Jameson K, Isaacs, Farren J, Kosuri, Sriram, Baker, David, Fields, Stanley, Church, George M, Raman, Srivatsan

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Computation-guided optimization of split protein systems von Dolberg, Taylor B., Meger, Anthony T., Boucher, Jonathan D., Corcoran, William K., Schauer, Elizabeth E., Prybutok, Alexis N., Raman, Srivatsan, Leonard, Joshua N.

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De novo design of programmable inducible promoters von Liu, Xiangyang, Gupta, Sanjan T P, Bhimsaria, Devesh, Reed, Jennifer L, Rodríguez-Martínez, José A, Ansari, Aseem Z, Raman, Srivatsan

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High-resolution structure prediction and the crystallographic phase problem von Qian, Bin, Raman, Srivatsan, Das, Rhiju, Bradley, Philip, McCoy, Airlie J., Read, Randy J., Baker, David

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NMR Structure Determination for Larger Proteins Using Backbone-Only Data von Raman, Srivatsan, Lange, Oliver F, Rossi, Paolo, Tyka, Michael, Wang, Xu, Aramini, James, Liu, Gaohua, Ramelot, Theresa A, Eletsky, Alexander, Szyperski, Thomas, Kennedy, Michael A, Prestegard, James, Montelione, Gaetano T, Baker, David

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Highly multiplexed design of an allosteric transcription factor to sense new ligands von Nishikawa, Kyle K., Chen, Jackie, Acheson, Justin F., Harbaugh, Svetlana V., Huss, Phil, Frenkel, Max, Novy, Nathan, Sieren, Hailey R., Lodewyk, Ella C., Lee, Daniel H., Chávez, Jorge L., Fox, Brian G., Raman, Srivatsan

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Systems Approaches to Understanding and Designing Allosteric Proteins von Raman, Srivatsan

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Engineered bacteriophages as programmable biocontrol agents von Huss, Phil, Raman, Srivatsan

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Discovering mechanisms of human genetic variation and controlling cell states at scale von Frenkel, Max, Raman, Srivatsan

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Designing highly specific protein‐based small molecule biosensors von Raman, Srivatsan

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Functional plasticity and evolutionary adaptation of allosteric regulation von Leander, Megan, Yuan, Yuchen, Meger, Anthony, Cui, Qiang, Raman, Srivatsan

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High-throughput approaches to understand and engineer bacteriophages von Huss, Phil, Chen, Jackie, Raman, Srivatsan

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Accurate Automated Protein NMR Structure Determination Using Unassigned NOESY Data von Raman, Srivatsan, Huang, Yuanpeng J, Mao, Binchen, Rossi, Paolo, Aramini, James M, Liu, Gaohua, Montelione, Gaetano T, Baker, David

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CASD-NMR: critical assessment of automated structure determination by NMR von Rosato, Antonio, Bagaria, Anurag, Baker, David, Bardiaux, Benjamin, Cavalli, Andrea, Doreleijers, Jurgen F, Giachetti, Andrea, Guerry, Paul, Güntert, Peter, Herrmann, Torsten, Huang, Yuanpeng J, Jonker, Hendrik R A, Mao, Binchen, Malliavin, Thérèse E, Montelione, Gaetano T, Nilges, Michael, Raman, Srivatsan, van der Schot, Gijs, Vranken, Wim F, Vuister, Geerten W, Bonvin, Alexandre M J J

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Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: Four approaches that performed well in CASP8 von Krieger, Elmar, Joo, Keehyoung, Lee, Jinwoo, Lee, Jooyoung, Raman, Srivatsan, Thompson, James, Tyka, Mike, Baker, David, Karplus, Kevin

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