Targeted Ablation, Silencing, and Activation Establish Glycinergic Dorsal Horn Neurons as Key Components of a Spinal Gate for Pain and Itch von Foster, Edmund, Wildner, Hendrik, Tudeau, Laetitia, Haueter, Sabine, Ralvenius, William T., Jegen, Monika, Johannssen, Helge, Hösli, Ladina, Haenraets, Karen, Ghanem, Alexander, Conzelmann, Karl-Klaus, Bösl, Michael, Zeilhofer, Hanns Ulrich

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Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors von Ralvenius, William T., Neumann, Elena, Pagani, Martina, Acuña, Mario A., Wildner, Hendrik, Benke, Dietmar, Fischer, Nina, Rostaher, Ana, Schwager, Simon, Detmar, Michael, Frauenknecht, Katrin, Aguzzi, Adriano, Hubbs, Jed Lee, Rudolph, Uwe, Favrot, Claude, Zeilhofer, Hanns Ulrich

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Modeling Alzheimer’s disease with iPSC-derived brain cells von Penney, Jay, Ralvenius, William T., Tsai, Li-Huei

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Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration von Morshed, Nader, Ralvenius, William T, Nott, Alexi, Watson, L Ashley, Rodriguez, Felicia H, Akay, Leyla A, Joughin, Brian A, Pao, Ping‐Chieh, Penney, Jay, LaRocque, Lauren, Mastroeni, Diego, Tsai, Li‐Huei, White, Forest M

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GABAA receptor subtypes in the mouse brain: Regional mapping and diazepam receptor occupancy by in vivo [18F]flumazenil PET von Müller Herde, Adrienne, Benke, Dietmar, Ralvenius, William T., Mu, Linjing, Schibli, Roger, Zeilhofer, Hanns Ulrich, Krämer, Stefanie D.

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APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes von Blanchard, Joel W., Akay, Leyla Anne, Davila-Velderrain, Jose, von Maydell, Djuna, Mathys, Hansruedi, Davidson, Shawn M., Effenberger, Audrey, Chen, Chih-Yu, Maner-Smith, Kristal, Hajjar, Ihab, Ortlund, Eric A., Bula, Michael, Agbas, Emre, Ng, Ayesha, Jiang, Xueqiao, Kahn, Martin, Blanco-Duque, Cristina, Lavoie, Nicolas, Liu, Liwang, Reyes, Ricardo, Lin, Yuan-Ta, Ko, Tak, R’Bibo, Lea, Ralvenius, William T., Bennett, David A., Cam, Hugh P., Kellis, Manolis, Tsai, Li-Huei

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Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype von Ralvenius, William T., Benke, Dietmar, Acuña, Mario A., Rudolph, Uwe, Zeilhofer, Hanns Ulrich

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Acetaminophen Relieves Inflammatory Pain through CB 1 Cannabinoid Receptors in the Rostral Ventromedial Medulla von Klinger-Gratz, Pascal P, Ralvenius, William T, Neumann, Elena, Kato, Ako, Nyilas, Rita, Lele, Zsolt, Katona, István, Zeilhofer, Hanns Ulrich

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Nanoparticle‐Mediated Delivery of Anti‐PU.1 siRNA via Localized Intracisternal Administration Reduces Neuroinflammation von Ralvenius, William T., Andresen, Jason L., Huston, Margaret M., Penney, Jay, Bonner, Julia Maeve, Fenton, Owen S., Langer, Robert, Tsai, Li‐Huei

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A virus-like particle-based anti-nerve growth factor vaccine reduces inflammatory hyperalgesia: potential long-term therapy for chronic pain von Röhn, Till A, Ralvenius, William T, Paul, Jolly, Borter, Petra, Hernandez, Marcela, Witschi, Robert, Grest, Paula, Zeilhofer, Hanns Ulrich, Bachmann, Martin F, Jennings, Gary T

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iPSC‐derived microglia carrying the TREM2 R47H/+ mutation are proinflammatory and promote synapse loss von Penney, Jay, Ralvenius, William T., Loon, Anjanet, Cerit, Oyku, Dileep, Vishnu, Milo, Blerta, Pao, Ping‐Chieh, Woolf, Hannah, Tsai, Li‐Huei

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Acetaminophen Relieves Inflammatory Pain through CB1 Cannabinoid Receptors in the Rostral Ventromedial Medulla von Klinger-Gratz, Pascal P., Ralvenius, William T., Neumann, Elena, Kato, Ako, Nyilas, Rita, Lele, Zsolt, Katona, István, Zeilhofer, Hanns Ulrich

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A novel PU.1 inhibitor for the treatment of Alzheimer’s disease von Ralvenius, William T, Tsai, Li‐Huei, Woolf, Hannah, Cam, Hugh, Mungenast, Alison

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A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation von Ralvenius, William T, Mungenast, Alison E, Woolf, Hannah, Huston, Margaret M, Gillingham, Tyler Z, Godin, Stephen K, Penney, Jay, Cam, Hugh P, Gao, Fan, Fernandez, Celia G, Czako, Barbara, Lightfoot, Yaima, Ray, William J, Beckmann, Adrian, Goate, Alison M, Marcora, Edoardo, Romero-Molina, Carmen, Ayata, Pinar, Schaefer, Anne, Gjoneska, Elizabeta, Tsai, Li-Huei

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The positive allosteric GABAB receptor modulator rac-BHFF enhances baclofen-mediated analgesia in neuropathic mice von Zemoura, Khaled, Ralvenius, William T., Malherbe, Pari, Benke, Dietmar

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Author Correction: APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes von Blanchard, Joel W., Akay, Leyla Anne, Davila-Velderrain, Jose, von Maydell, Djuna, Mathys, Hansruedi, Davidson, Shawn M., Effenberger, Audrey, Chen, Chih-Yu, Maner-Smith, Kristal, Hajjar, Ihab, Ortlund, Eric A., Bula, Michael, Agbas, Emre, Ng, Ayesha, Jiang, Xueqiao, Kahn, Martin, Blanco-Duque, Cristina, Lavoie, Nicolas, Liu, Liwang, Reyes, Ricardo, Lin, Yuan-Ta, Ko, Tak, R’Bibo, Lea, Ralvenius, William T., Bennett, David A., Cam, Hugh P., Kellis, Manolis, Tsai, Li-Huei

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Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain von Acuña, Mario A, Yévenes, Gonzalo E, Ralvenius, William T, Benke, Dietmar, Di Lio, Alessandra, Lara, Cesar O, Muñoz, Braulio, Burgos, Carlos F, Moraga-Cid, Gustavo, Corringer, Pierre-Jean, Zeilhofer, Hanns Ulrich

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TP003 is a non-selective benzodiazepine site agonist that induces anxiolysis via α2GABAA receptors von Neumann, Elena, Ralvenius, William T., Acuña, Mario A., Rudolph, Uwe, Zeilhofer, Hanns Ulrich

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Mice lacking spinal α2GABAA receptors: Altered GABAergic neurotransmission, diminished GABAergic antihyperalgesia, and potential compensatory mechanisms preventing a hyperalgesic p... von Tudeau, Laetitia, Acuña, Mario A., Albisetti, Gioele W., Neumann, Elena, Ralvenius, William T., Scheurer, Louis, Poe, Michael, Cook, James M., Johannssen, Helge C., Zeilhofer, Hanns Ulrich

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The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia von Ralvenius, William T., Acuña, Mario A., Benke, Dietmar, Matthey, Alain, Daali, Youssef, Rudolph, Uwe, Desmeules, Jules, Zeilhofer, Hanns Ulrich, Besson, Marie

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