Small Rho GTPases in the control of cell shape and mobility von Murali, Arun, Rajalingam, Krishnaraj

Volltext

Prohibitin ligands: a growing armamentarium to tackle cancers, osteoporosis, inflammatory, cardiac and neurological diseases von Wang, Dong, Tabti, Redouane, Elderwish, Sabria, Abou-Hamdan, Hussein, Djehal, Amel, Yu, Peng, Yurugi, Hajime, Rajalingam, Krishnaraj, Nebigil, Canan G., Désaubry, Laurent

Volltext

Druggable genome and precision medicine in cancer: current challenges von Dupont, Camille Amandine, Riegel, Kristina, Pompaiah, Malvika, Juhl, Hartmut, Rajalingam, Krishnaraj

Volltext

ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization von Bogucka-Janczi, Katarzyna, Harms, Gregory, Coissieux, Marie-May, Bentires-Alj, Mohamed, Thiede, Bernd, Rajalingam, Krishnaraj

Volltext

Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas von Krishnan, Aswini, Berthelet, Jean, Renaud, Emilie, Rosigkeit, Sebastian, Distler, Ute, Stawiski, Eric, Wang, Jing, Modrusan, Zora, Fiedler, Marc, Bienz, Mariann, Tenzer, Stefan, Schad, Arno, Roth, Wilfried, Thiede, Bernd, Seshagiri, Somasekar, Musholt, Thomas J., Rajalingam, Krishnaraj

Volltext

ERK5 modulates IL-6 secretion and contributes to tumor-induced immune suppression von Riegel, Kristina, Yurugi, Hajime, Schlöder, Janine, Jonuleit, Helmut, Kaulich, Manuel, Kirschner, Friederike, Arnold-Schild, Danielle, Tenzer, Stefan, Schild, Hansjörg, Rajalingam, Krishnaraj

Volltext

Flotillin-1/Reggie-2 Protein Plays Dual Role in Activation of Receptor-tyrosine Kinase/Mitogen-activated Protein Kinase Signaling von Amaddii, Monia, Meister, Melanie, Banning, Antje, Tomasovic, Ana, Mooz, Juliane, Rajalingam, Krishnaraj, Tikkanen, Ritva

Volltext

RAF kinases are stabilized and required for dendritic cell differentiation and function von Riegel, Kristina, Schlöder, Janine, Sobczak, Marco, Jonuleit, Helmut, Thiede, Bernd, Schild, Hansjörg, Rajalingam, Krishnaraj

Volltext

Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection von Mukherjee, Rukmini, Bhattacharya, Anshu, Bojkova, Denisa, Mehdipour, Ahmad Reza, Shin, Donghyuk, Khan, Khadija Shahed, Hei-Yin Cheung, Hayley, Wong, Kam-Bo, Ng, Wai-Lung, Cinatl, Jindrich, Geurink, Paul P., van der Heden van Noort, Gerbrand J., Rajalingam, Krishnaraj, Ciesek, Sandra, Hummer, Gerhard, Dikic, Ivan

Volltext

ERK3/MAPK6 controls IL-8 production and chemotaxis von Bogucka, Katarzyna, Pompaiah, Malvika, Marini, Federico, Binder, Harald, Harms, Gregory, Kaulich, Manuel, Klein, Matthias, Michel, Christian, Radsak, Markus P, Rosigkeit, Sebastian, Grimminger, Peter, Schild, Hansjörg, Rajalingam, Krishnaraj

Volltext

The Myb-related protein MYPOP is a novel intrinsic host restriction factor of oncogenic human papillomaviruses von Wüstenhagen, Elena, Boukhallouk, Fatima, Negwer, Inka, Rajalingam, Krishnaraj, Stubenrauch, Frank, Florin, Luise

Volltext

Targeting prohibitins at the cell surface prevents Th17‐mediated autoimmunity von Buehler, Ulrike, Schulenburg, Katharina, Yurugi, Hajime, Šolman, Maja, Abankwa, Daniel, Ulges, Alexander, Tenzer, Stefan, Bopp, Tobias, Thiede, Bernd, Zipp, Frauke, Rajalingam, Krishnaraj

Volltext

The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions von Eichler, Madeleine, Distler, Ute, Nasrullah, Usman, Krishnan, Aswini, Kaulich, Manuel, Husnjak, Koraljka, Eberhardt, Wolfgang, Rajalingam, Krishnaraj, Tenzer, Stefan, Pfeilschifter, Josef, Imre, Gergely

Volltext

Integrate and conquer: pan-cancer proteogenomics uncovers cancer vulnerabilities and therapeutic opportunities von Chakraborty, Debomita, Romero, Rossana, Rajalingam, Krishnaraj

Volltext

SAMHD1 in cancer: curse or cure? von Schott, Kerstin, Majer, Catharina, Bulashevska, Alla, Childs, Liam, Schmidt, Mirko H. H., Rajalingam, Krishnaraj, Munder, Markus, König, Renate

Volltext

A blood transcriptome-based analysis of disease progression, immune regulation, and symptoms in coronavirus-infected patients von Sadanandam, Anguraj, Bopp, Tobias, Dixit, Santosh, Knapp, David J. H. F., Emperumal, Chitra Priya, Vergidis, Paschalis, Rajalingam, Krishnaraj, Melcher, Alan, Kannan, Nagarajan

Volltext

Multiomic analysis of papillary thyroid cancers identifies BAIAP2L1-BRAF fusion and requirement of TRIM25, PDE5A and PKCδ for tumorigenesis von Renaud, Emilie, Riegel, Kristina, Romero, Rossana, Suryamohan, Kushal, Distler, Ute, Tenzer, Stefan, Schad, Arno, Musholt, Thomas J., Rajalingam, Krishnaraj

Volltext

Cationic Amino Acid Transporter-1-Mediated Arginine Uptake Is Essential for Chronic Lymphocytic Leukemia Cell Proliferation and Viability von Werner, Anke, Pieh, Daniel, Echchannaoui, Hakim, Rupp, Johanna, Rajalingam, Krishnaraj, Theobald, Matthias, Closs, Ellen I, Munder, Markus

Volltext

The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in multiple myeloma von Crawford, Lisa J., Campbell, David C., Morgan, Jonathan J., Lawson, Michelle A., Down, Jennifer M., Chauhan, Dharminder, McAvera, Roisin M., Morris, Treen C., Hamilton, Claudia, Krishnan, Aswini, Rajalingam, Krishnaraj, Chantry, Andrew D., Irvine, Alexandra E.

Volltext

ERK3/MAPK6 is required for KRAS-mediated NSCLC tumorigenesis von Bogucka, Katarzyna, Marini, Federico, Rosigkeit, Sebastian, Schloeder, Janine, Jonuleit, Helmut, David, Kerstin, Schlackow, Margarita, Rajalingam, Krishnaraj

Volltext