Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway von Bumcrot, David, John, Matthias, Constien, Rainer, Akinc, Akin, Goldberg, Michael, Moon, Young-Ah, Spranger, Martina, Hadwiger, Philipp, Soutschek, Jürgen, Vornlocher, Hans-Peter, Manoharan, Muthiah, Stoffel, Markus, Langer, Robert, Anderson, Daniel G, Horton, Jay D, Koteliansky, Victor

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Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line von Constien, Rainer, Forde, Anne, Liliensiek, Birgit, Gröne, Hermann-Josef, Nawroth, Peter, Hämmerling, Günter, Arnold, Bernd

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Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements von Forde, Anne, Constien, Rainer, Gröne, Hermann-Josef, Hämmerling, Günter, Arnold, Bernd

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A combinatorial library of lipid-like materials for delivery of RNAi therapeutics von Anderson, Daniel G, Akinc, Akin, Zumbuehl, Andreas, Goldberg, Michael, Leshchiner, Elizaveta S, Busini, Valentina, Hossain, Naushad, Bacallado, Sergio A, Nguyen, David N, Fuller, Jason, Alvarez, Rene, Borodovsky, Anna, Borland, Todd, Constien, Rainer, de Fougerolles, Antonin, Dorkin, J Robert, Narayanannair Jayaprakash, K, Jayaraman, Muthusamy, John, Matthias, Koteliansky, Victor, Manoharan, Muthiah, Nechev, Lubomir, Qin, June, Racie, Timothy, Raitcheva, Denitza, Rajeev, Kallanthottathil G, Sah, Dinah W Y, Soutschek, Jürgen, Toudjarska, Ivanka, Vornlocher, Hans-Peter, Zimmermann, Tracy S, Langer, Robert

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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs von Soutschek, Jürgen, Akinc, Akin, Bramlage, Birgit, Charisse, Klaus, Constien, Rainer, Donoghue, Mary, Elbashir, Sayda, Geick, Anke, Hadwiger, Philipp, Harborth, Jens, John, Matthias, Kesavan, Venkitasamy, Lavine, Gary, Pandey, Rajendra K, Racie, Timothy, Rajeev, Kallanthottathil G, Röhl, Ingo, Toudjarska, Ivanka, Wang, Gang, Wuschko, Silvio, Bumcrot, David, Koteliansky, Victor, Limmer, Stefan, Manoharan, Muthiah, Vornlocher, Hans-Peter

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The Minipig is a Suitable Non-Rodent Model in the Safety Assessment of Single Stranded Oligonucleotides von Braendli-Baiocco, A, Festag, M, Dumong-Erichsen, K, Persson, R, Mihatsch, MJ, Fisker, N, Funk, J, Mohr, S, Constien, R, Ploix, C, Brady, K, Berrera, M, Altmann, B, Lenz, B, Albassam, M, Schmitt, G, Weiser, T, Schuler, F, Singer, T, Tessier, Y

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Autoimmunity and inflammation due to a gain-of-function mutation in phospholipase C gamma 2 that specifically increases external Ca2+ entry von Yu, Philipp, Constien, Rainer, Dear, Neil, Katan, Matilda, Hanke, Petra, Bunney, Tom D, Kunder, Sandra, Quintanilla-Martinez, Leticia, Huffstadt, Ulrike, Schröder, Andreas, Jones, Neil P, Peters, Thomas, Fuchs, Helmut, de Angelis, Martin Hrabe, Nehls, Michael, Grosse, Johannes, Wabnitz, Philipp, Meyer, Thomas P H, Yasuda, Kei, Schiemann, Matthias, Schneider-Fresenius, Christian, Jagla, Wolfgang, Russ, Andreas, Popp, Andreas, Josephs, Michelle, Marquardt, Andreas, Laufs, Jürgen, Schmittwolf, Carolin, Wagner, Hermann, Pfeffer, Klaus, Mudde, Geert C

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From the Cover: The Minipig is a Suitable Non-Rodent Model in the Safety Assessment of Single Stranded Oligonucleotides von Braendli-Baiocco, Annamaria, Festag, Matthias, Dumong Erichsen, Kamille, Persson, Robert, Mihatsch, Michael J, Fisker, Niels, Funk, Juergen, Mohr, Susanne, Constien, Rainer, Ploix, Corinne, Brady, Kevin, Berrera, Marco, Altmann, Bernd, Lenz, Barbara, Albassam, Mudher, Schmitt, Georg, Weiser, Thomas, Schuler, Franz, Singer, Thomas, Tessier, Yann

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The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis von Lu, Ping, Hankel, Isaiah L, Knisz, Judit, Marquardt, Andreas, Chiang, Ming-Yi, Grosse, Johannes, Constien, Rainer, Meyer, Thomas, Schroeder, Andreas, Zeitlmann, Lutz, Al-Alem, Umaima, Friedman, Ann D, Elliott, Eric I, Meyerholz, David K, Waldschmidt, Thomas J, Rothman, Paul B, Colgan, John D

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Embryonic expression and characterization of a Ptx1 homolog in Drosophila von Vorbrüggen, Gerd, Constien, Rainer, Zilian, Olav, Wimmer, Ernst A, Dowe, Gordon, Taubert, Heike, Noll, Markus, Jäckle, Herbert

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Autoimmunity and Inflammation Due to a Gain-of-Function Mutation in Phospholipase Cγ2 that Specifically Increases External Ca2+ Entry von Yu, Philipp, Constien, Rainer, Dear, Neil, Katan, Matilda, Hanke, Petra, Bunney, Tom D., Kunder, Sandra, Quintanilla-Martinez, Leticia, Huffstadt, Ulrike, Schröder, Andreas, Jones, Neil P., Peters, Thomas, Fuchs, Helmut, Hrabe de Angelis, Martin, Nehls, Michael, Grosse, Johannes, Wabnitz, Philipp, Meyer, Thomas P.H., Yasuda, Kei, Schiemann, Matthias, Schneider-Fresenius, Christian, Jagla, Wolfgang, Russ, Andreas, Popp, Andreas, Josephs, Michelle, Marquardt, Andreas, Laufs, Jürgen, Schmittwolf, Carolin, Wagner, Hermann, Pfeffer, Klaus, Mudde, Geert C.

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Autoimmunity and Inflammation Due to a Gain-of-Function Mutation in Phospholipase C[gamma]2 that Specifically Increases External Ca2+ Entry von Yu, Philipp, Constien, Rainer, Dear, Neil, Katan, Matilda, Hanke, Petra, Bunney, Tom D, Kunder, Sandra, Quintanilla-Martinez, Leticia, Huffstadt, Ulrike, Schröder, Andreas, Jones, Neil P, Peters, Thomas, Fuchs, Helmut, Hrabe de Angelis, Martin, Nehls, Michael, Grosse, Johannes, Wabnitz, Philipp, Meyer, Thomas PH, Yasuda, Kei, Schiemann, Matthias, Schneider-Fresenius, Christian, Jagla, Wolfgang, Russ, Andreas, Popp, Andreas, Josephs, Michelle, Marquardt, Andreas, Laufs, Jürgen, Schmittwolf, Carolin, Wagner, Hermann, Pfeffer, Klaus, Mudde, Geert C

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Autoimmunity and Inflammation Due to a Gain-of-Function Mutation in Phospholipase Cγ2 that Specifically Increases External Ca 2+ Entry von Yu, Philipp, Constien, Rainer, Dear, Neil, Katan, Matilda, Hanke, Petra, Bunney, Tom D., Kunder, Sandra, Quintanilla-Martinez, Leticia, Huffstadt, Ulrike, Schröder, Andreas, Jones, Neil P., Peters, Thomas, Fuchs, Helmut, Hrabe de Angelis, Martin, Nehls, Michael, Grosse, Johannes, Wabnitz, Philipp, Meyer, Thomas P.H., Yasuda, Kei, Schiemann, Matthias, Schneider-Fresenius, Christian, Jagla, Wolfgang, Russ, Andreas, Popp, Andreas, Josephs, Michelle, Marquardt, Andreas, Laufs, Jürgen, Schmittwolf, Carolin, Wagner, Hermann, Pfeffer, Klaus, Mudde, Geert C.

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composições e métodos para inibir expressão de genes de receptor de glicocorticóide (gcr) von Brigitte Schott, Rainer Constien, Birgit Bramlage, Jacques Bailly, Markus Hossbach, Agnès Bénardeau, Andrea Forst

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RNAi MODULATION OF TGF-BETA AND THERAPEUTIC USES THEREOF von TAN, PAMELA, CONSTIEN, RAINER, VORNLOCHER, HANS-PETER

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RNAi Modulation Of TGF-BETA And Therapeutic Uses Thereof von TAN PAMELA, VORNLOCHER HANS-PETER, CONSTIEN RAINER

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Lipids and compositions for intracellular delivery of biologically active compounds von Weide Timo, Ickenstein Ludger, Hadwiger Philipp, Geick Anke, Constien Rainer, Schuster Andrea, Haneke Torsten, Hernandez Prata Carla Alexandra

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NOVEL LIPIDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS von HADWIGER Philipp, SCHUSTER Andrea, GEICK Anke, HANEKE Torsten, CONSTIEN Rainer, ICKENSTEIN Ludger, WEIDE Timo, HERNANDEZ PRATA Carla Alexandra

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Composições e métodos para inibir a expressão dos genes de fator vii von MARKUS HOSSBACH, HANS-PETER VORNLOCHER, RAINER CONSTIEN, JACQUES HIMBER, BIRGIT BRAMLAGE, PAMELA TAN

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Lipids and compositions for intracellular delivery of biologically active compounds von Weide Timo, Hadwiger Philipp, Geick Anke, Constien Rainer, Schuster Andrea, Haneke Torsten, Hernandez Prata Carla Alexandra, Ickenstein Ludger Markus

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