Synthesis and in vitro evaluation of novel 8-aminoquinoline–pyrazolopyrimidine hybrids as potent antimalarial agents von Kannan, Murugan, Raichurkar, Anandkumar V., Khan, Fazlur Rahman Nawaz, Iyer, Pravin S.

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Aminopyrazinamides: Novel and Specific GyrB Inhibitors that Kill Replicating and Nonreplicating Mycobacterium tuberculosis von Shirude, Pravin S, Madhavapeddi, Prashanti, Tucker, Julie A, Murugan, Kannan, Patil, Vikas, Basavarajappa, Halesha, Raichurkar, Anandkumar V, Humnabadkar, Vaishali, Hussein, Syeed, Sharma, Sreevalli, Ramya, V. K, Narayan, Chandan B, Balganesh, Tanjore S, Sambandamurthy, Vasan K

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Assessment of Mycobacterium tuberculosis Pantothenate Kinase Vulnerability through Target Knockdown and Mechanistically Diverse Inhibitors von KISHORE REDDY, B. K, LANDGE, Sudhir, AMBADY, Anisha, GHOSH, Anirban, TUNDUGURU, Ragadeepthi, KAUR, Parvinder, SINGH, Ragini, KUMAR, Naveen, BHARATH, Sowmya, SUNDARAM, Aishwarya, BHAT, Jyothi, SAMBANDAMURTHY, Vasan K, RAVISHANKAR, Sudha, BJÖRKELID, Christofer, ALWYN JONES, T, DAS, Kaveri, BANDODKAR, Balachandra, MALOLANARASIMHAN, Krishnan, MUKHERJEE, Kakoli, RAMACHANDRAN, Vasanthi, PATIL, Vikas, SHINDE, Vikas, TANTRY, Subramanyam, KALE, Manoj, RAICHURKAR, Anandkumar, MENASINAKAI, Sreenivasaiah, NAINA VINAY MUDUGAL

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Pyrazolopyrimidines Establish MurC as a Vulnerable Target in Pseudomonas aeruginosa and Escherichia coli von Hameed P, Shahul, Manjrekar, Praveena, Chinnapattu, Murugan, Humnabadkar, Vaishali, Shanbhag, Gajanan, Kedari, Chaitanyakumar, Mudugal, Naina Vinay, Ambady, Anisha, de Jonge, Boudewijn L.M, Sadler, Claire, Paul, Beena, Sriram, Shubha, Kaur, Parvinder, Guptha, Supreeth, Raichurkar, Anandkumar, Fleming, Paul, Eyermann, Charles J, McKinney, David C, Sambandamurthy, Vasan K, Panda, Manoranjan, Ravishankar, Sudha

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Discovery of Imidazo[1,2‑a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis von Tantry, Subramanyam J, Markad, Shankar D, Shinde, Vikas, Bhat, Jyothi, Balakrishnan, Gayathri, Gupta, Amit K, Ambady, Anisha, Raichurkar, Anandkumar, Kedari, Chaitanyakumar, Sharma, Sreevalli, Mudugal, Naina V, Narayan, Ashwini, Naveen Kumar, C. N, Nanduri, Robert, Bharath, Sowmya, Reddy, Jitendar, Panduga, Vijender, Prabhakar, K. R, Kandaswamy, Karthikeyan, Saralaya, Ramanatha, Kaur, Parvinder, Dinesh, Neela, Guptha, Supreeth, Rich, Kirsty, Murray, David, Plant, Helen, Preston, Marian, Ashton, Helen, Plant, Darren, Walsh, Jarrod, Alcock, Peter, Naylor, Kathryn, Collier, Matthew, Whiteaker, James, McLaughlin, Robert E, Mallya, Meenakshi, Panda, Manoranjan, Rudrapatna, Suresh, Ramachandran, Vasanthi, Shandil, Radha, Sambandamurthy, Vasan K, Mdluli, Khisi, Cooper, Christopher B, Rubin, Harvey, Yano, Takahiro, Iyer, Pravin, Narayanan, Shridhar, Kavanagh, Stefan, Mukherjee, Kakoli, Balasubramanian, V, Hosagrahara, Vinayak P, Solapure, Suresh, Ravishankar, Sudha, Hameed P, Shahul

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Discovery of Pyrazolopyridones as a Novel Class of Noncovalent DprE1 Inhibitor with Potent Anti-Mycobacterial Activity von Panda, Manoranjan, Ramachandran, Sreekanth, Ramachandran, Vasanthi, Shirude, Pravin S, Humnabadkar, Vaishali, Nagalapur, Kavitha, Sharma, Sreevalli, Kaur, Parvinder, Guptha, Supreeth, Narayan, Ashwini, Mahadevaswamy, Jyothi, Ambady, Anisha, Hegde, Naina, Rudrapatna, Suresh S, Hosagrahara, Vinayak P, Sambandamurthy, Vasan K, Raichurkar, Anandkumar

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Design and synthesis of triazolopyrimidine acylsulfonamides as novel anti-mycobacterial leads acting through inhibition of acetohydroxyacid synthase von Patil, Vikas, Kale, Manoj, Raichurkar, Anandkumar, Bhaskar, Brahatheeswaran, Prahlad, Dwarakanath, Balganesh, Meenakshi, Nandan, Santosh, Shahul Hameed, P.

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Structure Guided Lead Generation for M. tuberculosis Thymidylate Kinase (Mtb TMK): Discovery of 3‑Cyanopyridone and 1,6-Naphthyridin-2-one as Potent Inhibitors von Naik, Maruti, Raichurkar, Anandkumar, Bandodkar, Balachandra S, Varun, Begur V, Bhat, Shantika, Kalkhambkar, Rajesh, Murugan, Kannan, Menon, Rani, Bhat, Jyothi, Paul, Beena, Iyer, Harini, Hussein, Syeed, Tucker, Julie A, Vogtherr, Martin, Embrey, Kevin J, McMiken, Helen, Prasad, Swati, Gill, Adrian, Ugarkar, Bheemarao G, Venkatraman, Janani, Read, Jon, Panda, Manoranjan

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Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate von Hameed P., Shahul, Solapure, Suresh, Patil, Vikas, Henrich, Philipp P., Magistrado, Pamela A., Bharath, Sowmya, Murugan, Kannan, Viswanath, Pavithra, Puttur, Jayashree, Srivastava, Abhishek, Bellale, Eknath, Panduga, Vijender, Shanbag, Gajanan, Awasthy, Disha, Landge, Sudhir, Morayya, Sapna, Koushik, Krishna, Saralaya, Ramanatha, Raichurkar, Anandkumar, Rautela, Nikhil, Roy Choudhury, Nilanjana, Ambady, Anisha, Nandishaiah, Radha, Reddy, Jitendar, Prabhakar, K. R., Menasinakai, Sreenivasaiah, Rudrapatna, Suresh, Chatterji, Monalisa, Jiménez-Díaz, María Belén, Martínez, María Santos, Sanz, Laura María, Coburn-Flynn, Olivia, Fidock, David A., Lukens, Amanda K., Wirth, Dyann F., Bandodkar, Balachandra, Mukherjee, Kakoli, McLaughlin, Robert E., Waterson, David, Rosenbrier-Ribeiro, Lyn, Hickling, Kevin, Balasubramanian, V., Warner, Peter, Hosagrahara, Vinayak, Dudley, Adam, Iyer, Pravin S., Narayanan, Shridhar, Kavanagh, Stefan, Sambandamurthy, Vasan K.

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Diarylthiazole: An Antimycobacterial Scaffold Potentially Targeting PrrB-PrrA Two-Component System von Bellale, Eknath, Naik, Maruti, VB, Varun, Ambady, Anisha, Narayan, Ashwini, Ravishankar, Sudha, Ramachandran, Vasanthi, Kaur, Parvinder, McLaughlin, Robert, Whiteaker, James, Morayya, Sapna, Guptha, Supreeth, Sharma, Sreevalli, Raichurkar, Anandkumar, Awasthy, Disha, Achar, Vijayshree, Vachaspati, Prakash, Bandodkar, Balachandra, Panda, Manoranjan, Chatterji, Monalisa

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Novel N‑Linked Aminopiperidine-Based Gyrase Inhibitors with Improved hERG and in Vivo Efficacy against Mycobacterium tuberculosis von Hameed P, Shahul, Patil, Vikas, Solapure, Suresh, Sharma, Umender, Madhavapeddi, Prashanti, Raichurkar, Anandkumar, Chinnapattu, Murugan, Manjrekar, Praveena, Shanbhag, Gajanan, Puttur, Jayashree, Shinde, Vikas, Menasinakai, Sreenivasaiah, Rudrapatana, Suresh, Achar, Vijayashree, Awasthy, Disha, Nandishaiah, Radha, Humnabadkar, Vaishali, Ghosh, Anirban, Narayan, Chandan, Ramya, V. K, Kaur, Parvinder, Sharma, Sreevalli, Werngren, Jim, Hoffner, Sven, Panduga, Vijender, Kumar, C. N. Naveen, Reddy, Jitendar, Kumar KN, Mahesh, Ganguly, Samit, Bharath, Sowmya, Bheemarao, Ugarkar, Mukherjee, Kakoli, Arora, Uma, Gaonkar, Sheshagiri, Coulson, Michelle, Waterson, David, Sambandamurthy, Vasan K, de Sousa, Sunita M

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Shared Consensus Machine Learning Models for Predicting Blood Stage Malaria Inhibition von Verras, Andreas, Waller, Chris L, Gedeck, Peter, Green, Darren V. S, Kogej, Thierry, Raichurkar, Anandkumar, Panda, Manoranjan, Shelat, Anang A, Clark, Julie, Guy, R. Kiplin, Papadatos, George, Burrows, Jeremy

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Thiazolopyridine Ureas as Novel Antitubercular Agents Acting through Inhibition of DNA Gyrase B von Kale, Manoj G, Raichurkar, Anandkumar, P, Shahul Hameed, Waterson, David, McKinney, David, Manjunatha, M. R, Kranthi, Usha, Koushik, Krishna, Jena, Lalit kumar, Shinde, Vikas, Rudrapatna, Suresh, Barde, Shubhada, Humnabadkar, Vaishali, Madhavapeddi, Prashanti, Basavarajappa, Halesha, Ghosh, Anirban, Ramya, VK, Guptha, Supreeth, Sharma, Sreevalli, Vachaspati, Prakash, Kumar, K.N. Mahesh, Giridhar, Jayashree, Reddy, Jitendar, Panduga, Vijender, Ganguly, Samit, Ahuja, Vijaykamal, Gaonkar, Sheshagiri, Kumar, C. N. Naveen, Ogg, Derek, Tucker, Julie A, Boriack-Sjodin, P. Ann, de Sousa, Sunita M, Sambandamurthy, Vasan K, Ghorpade, Sandeep R

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Benzimidazoles: Novel Mycobacterial Gyrase Inhibitors from Scaffold Morphing von Hameed P, Shahul, Raichurkar, Anandkumar, Madhavapeddi, Prashanti, Menasinakai, Sreenivasaiah, Sharma, Sreevalli, Kaur, Parvinder, Nandishaiah, Radha, Panduga, Vijender, Reddy, Jitendar, Sambandamurthy, Vasan K, Sriram, D

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N‑Aryl-2-aminobenzimidazoles: Novel, Efficacious, Antimalarial Lead Compounds von Ramachandran, Sreekanth, Hameed P, Shahul, Srivastava, Abhishek, Shanbhag, Gajanan, Morayya, Sapna, Rautela, Nikhil, Awasthy, Disha, Kavanagh, Stefan, Bharath, Sowmya, Reddy, Jitendar, Panduga, Vijender, Prabhakar, K. R, Saralaya, Ramanatha, Nanduri, Robert, Raichurkar, Anandkumar, Menasinakai, Sreenivasaiah, Achar, Vijayashree, Jiménez-Díaz, María Belén, Martínez, María Santos, Angulo-Barturen, Iñigo, Ferrer, Santiago, Sanz, Laura María, Gamo, Francisco Javier, Duffy, Sandra, Avery, Vicky M, Waterson, David, Lee, Marcus C. S, Coburn-Flynn, Olivia, Fidock, David A, Iyer, Pravin S, Narayanan, Shridhar, Hosagrahara, Vinayak, Sambandamurthy, Vasan K

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Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity von Landge, Sudhir, Ramachandran, Vasanthi, Kumar, Anupriya, Neres, João, Murugan, Kannan, Sadler, Claire, Fellows, Mick D., Humnabadkar, Vaishali, Vachaspati, Prakash, Raichurkar, Anandkumar, Sharma, Sreevalli, Ravishankar, Sudha, Guptha, Supreeth, Sambandamurthy, Vasan K., Balganesh, Tanjore S., Ugarkar, Bheemarao G., Balasubramanian, V., Bandodkar, Balachandra S., Panda, Manoranjan

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Thiazolopyridone ureas as DNA gyrase B inhibitors: Optimization of antitubercular activity and efficacy von Kale, Ramesh R., Kale, Manoj G., Waterson, David, Raichurkar, Anandkumar, Hameed, Shahul P., Manjunatha, M.R., Kishore Reddy, B.K., Malolanarasimhan, Krishnan, Shinde, Vikas, Koushik, Krishna, Jena, Lalit Kumar, Menasinakai, Sreenivasaiah, Humnabadkar, Vaishali, Madhavapeddi, Prashanti, Basavarajappa, Halesha, Sharma, Sreevalli, Nandishaiah, Radha, Mahesh Kumar, K.N., Ganguly, Samit, Ahuja, Vijaykamal, Gaonkar, Sheshagiri, Naveen Kumar, C.N., Ogg, Derek, Boriack-Sjodin, P. Ann, Sambandamurthy, Vasan K., de Sousa, Sunita M., Ghorpade, Sandeep R.

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Aminoazabenzimidazoles, a Novel Class of Orally Active Antimalarial Agents von Hameed P, Shahul, Chinnapattu, Murugan, Shanbag, Gajanan, Manjrekar, Praveena, Koushik, Krishna, Raichurkar, Anandkumar, Patil, Vikas, Jatheendranath, Sandesh, Rudrapatna, Suresh S, Barde, Shubhada P, Rautela, Nikhil, Awasthy, Disha, Morayya, Sapna, Narayan, Chandan, Kavanagh, Stefan, Saralaya, Ramanatha, Bharath, Sowmya, Viswanath, Pavithra, Mukherjee, Kakoli, Bandodkar, Balachandra, Srivastava, Abhishek, Panduga, Vijender, Reddy, Jitender, Prabhakar, K. R, Sinha, Achyut, Jiménez-Díaz, María Belén, Martínez, María Santos, Angulo-Barturen, Iñigo, Ferrer, Santiago, Sanz, Laura María, Gamo, Francisco Javier, Duffy, Sandra, Avery, Vicky M, Magistrado, Pamela A, Lukens, Amanda K, Wirth, Dyann F, Waterson, David, Balasubramanian, V, Iyer, Pravin S, Narayanan, Shridhar, Hosagrahara, Vinayak, Sambandamurthy, Vasan K, Ramachandran, Sreekanth

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Synthesis and antibacterial activity of some 5-guanylhydrazone/thiocyanato-6-arylimidazo[2,1-b]-1,3,4-thiadiazole-2-sulfonamide derivatives von Gadad, Andanappa K, Mahajanshetti, Chanabasappa S, Nimbalkar, Sudarshan, Raichurkar, Anandkumar

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Novel lead generation of an anti-tuberculosis agent active against non-replicating mycobacteria: exploring hybridization of pyrazinamide with multiple fragments von Markad, Shankar D., Kaur, Parvinder, Kishore Reddy, B. K., Chinnapattu, Murugan, Raichurkar, Anandkumar, Nandishaiah, Radha, Panda, Manoranjan, Iyer, Pravin S.

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