CD33‐directed immunotherapy with third‐generation chimeric antigen receptor T cells and gemtuzumab ozogamicin in intact and CD33‐edited acute myeloid leukemia and hematopoietic ste... von Liu, Yi, Wang, Sanmei, Schubert, Maria‐Luisa, Lauk, Annika, Yao, Hao, Blank, Maximilian Felix, Cui, Chunhong, Janssen, Maike, Schmidt, Christina, Göllner, Stefanie, Kleist, Christian, Zhou, Fengbiao, Rahfeld, Jens‐Ulrich, Sauer, Tim, Schmitt, Michael, Müller‐Tidow, Carsten

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Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme von Gnoth, Kathrin, Bär, Joachim Wolfgang, Rosche, Fred, Rahfeld, Jens-Ulrich, Demuth, Hans-Ulrich

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Passive Aβ Immunotherapy: Current Achievements and Future Perspectives von Schilling, Stephan, Rahfeld, Jens-Ulrich, Lues, Inge, Lemere, Cynthia A

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Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life von Uhlmann, Ruth E., Rother, Christine, Rasmussen, Jay, Schelle, Juliane, Bergmann, Carina, Ullrich Gavilanes, Emily M., Fritschi, Sarah K., Buehler, Anika, Baumann, Frank, Skodras, Angelos, Al-Shaana, Rawaa, Beschorner, Natalie, Ye, Lan, Kaeser, Stephan A., Obermüller, Ulrike, Christensen, Søren, Kartberg, Fredrik, Stavenhagen, Jeffrey B., Rahfeld, Jens-Ulrich, Cynis, Holger, Qian, Fang, Weinreb, Paul H., Bussiere, Thierry, Walker, Lary C., Staufenbiel, Matthias, Jucker, Mathias

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Development of the clinical candidate PBD-C06, a humanized pGlu3-Aβ-specific antibody against Alzheimer’s disease with reduced complement activation von Hettmann, Thore, Gillies, Stephen D., Kleinschmidt, Martin, Piechotta, Anke, Makioka, Koki, Lemere, Cynthia A., Schilling, Stephan, Rahfeld, Jens-Ulrich, Lues, Inge

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Combination of the Glutaminyl Cyclase Inhibitor PQ912 (Varoglutamstat) and the Murine Monoclonal Antibody PBD-C06 (m6) Shows Additive Effects on Brain A beta Pathology in Transgeni... von Hoffmann, Torsten, Rahfeld, Jens-Ulrich, Schenk, Mathias, Ponath, Falk, Makioka, Koki, Hutter-Paier, Birgit, Lues, Inge, Lemere, Cynthia A., Schilling, Stephan

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Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor von Parthier, Christoph, Kleinschmidt, Martin, Neumann, Piotr, Rudolph, Rainer, Manhart, Susanne, Schlenzig, Dagmar, Fanghänel, Jörg, Rahfeld, Jens-Ulrich, Demuth, Hans-Ulrich, Stubbs, Milton T

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Enhanced Fibril Fragmentation of N-Terminally Truncated and Pyroglutamyl-Modified Aβ Peptides von Wulff, Melanie, Baumann, Monika, Thümmler, Anka, Yadav, Jay K., Heinrich, Liesa, Knüpfer, Uwe, Schlenzig, Dagmar, Schierhorn, Angelika, Rahfeld, Jens-Ulrich, Horn, Uwe, Balbach, Jochen, Demuth, Hans-Ulrich, Fändrich, Marcus

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Tetrahydroimidazo[4,5-c]pyridine-Based Inhibitors of Porphyromonas gingivalis Glutaminyl Cyclase von Ramsbeck, Daniel, Taudte, Nadine, Jaenckel, Nadine, Strich, Stefanie, Rahfeld, Jens-Ulrich, Buchholz, Mirko

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Effector function of anti-pyroglutamate-3 A beta antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer's-like mice von Crehan, Helen, Liu, Bin, Kleinschmidt, Martin, Rahfeld, Jens-Ulrich, Le, Kevin X., Caldarone, Barbara J., Frost, Jeffrey L., Hettmann, Thore, Hutter-Paier, Birgit, O'Nuallain, Brian, Park, Mi-Ae, DiCarli, Marcelo F., Lues, Inge, Schilling, Stephan, Lemere, Cynthia A.

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The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions von Cynis, Holger, Hoffmann, Torsten, Friedrich, Daniel, Kehlen, Astrid, Gans, Kathrin, Kleinschmidt, Martin, Rahfeld, Jens‐Ulrich, Wolf, Raik, Wermann, Michael, Stephan, Anett, Haegele, Monique, Sedlmeier, Reinhard, Graubner, Sigrid, Jagla, Wolfgang, Müller, Anke, Eichentopf, Rico, Heiser, Ulrich, Seifert, Franziska, Quax, Paul H. A., de Vries, Margreet R., Hesse, Isabel, Trautwein, Daniela, Wollert, Ulrich, Berg, Sabine, Freyse, Ernst‐Joachim, Schilling, Stephan, Demuth, Hans‐Ulrich

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Consequences of Amyloid‐β Deficiency for the Liver von Buniatian, Gayane Hrachia, Schwinghammer, Ute, Tremmel, Roman, Cynis, Holger, Weiss, Thomas S., Weiskirchen, Ralf, Lauschke, Volker M., Youhanna, Sonia, Ramos, Isbaal, Valcarcel, Maria, Seferyan, Torgom, Rahfeld, Jens‐Ulrich, Rieckmann, Vera, Klein, Kathrin, Buadze, Marine, Weber, Victoria, Kolak, Valentina, Gebhardt, Rolf, Friedman, Scott L., Müller, Ulrike C., Schwab, Matthias, Danielyan, Lusine

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Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion von Schulz, Ingo, Zeitschel, Ulrike, Rudolph, Thomas, Ruiz‐Carrillo, David, Rahfeld, Jens‐Ulrich, Gerhartz, Bernd, Bigl, Volker, Demuth, Hans‐Ulrich, Roßner, Steffen

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Neuropeptide Y (NPY) in cerebrospinal fluid from patients with Huntington's Disease: increased NPY levels and differential degradation of the NPY1–30 fragment von Wagner, Leona, Björkqvist, Maria, Lundh, Sofia Hult, Wolf, Raik, Börgel, Arne, Schlenzig, Dagmar, Ludwig, Hans‐Henning, Rahfeld, Jens‐Ulrich, Leavitt, Blair, Demuth, Hans‐Ulrich, Petersén, Åsa, Hörsten, Stephan

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Proteolytic degradation of neuropeptide Y (NPY) from head to toe: Identification of novel NPY‐cleaving peptidases and potential drug interactions in CNS and Periphery von Wagner, Leona, Wolf, Raik, Zeitschel, Ulrike, Rossner, Steffen, Petersén, Åsa, Leavitt, Blair R., Kästner, Florian, Rothermundt, Matthias, Gärtner, Ulf‐Torsten, Gündel, Daniel, Schlenzig, Dagmar, Frerker, Nadine, Schade, Jutta, Manhart, Susanne, Rahfeld, Jens‐Ulrich, Demuth, Hans‐Ulrich, Hörsten, Stephan

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Immunohistochemical Evidence from APP-Transgenic Mice for Glutaminyl Cyclase as Drug Target to Diminish pE-Abeta Formation von Hartlage-Rübsamen, Maike, Bluhm, Alexandra, Piechotta, Anke, Linnert, Miriam, Rahfeld, Jens-Ulrich, Demuth, Hans-Ulrich, Lues, Inge, Kuhn, Peer-Hendrik, Lichtenthaler, Stefan F, Roßner, Steffen, Höfling, Corinna

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Bcl‐2 regulator FKBP38 is activated by Ca2+/calmodulin von Edlich, Frank, Weiwad, Matthias, Erdmann, Frank, Fanghänel, Jörg, Jarczowski, Franziska, Rahfeld, Jens‐Ulrich, Fischer, Gunter

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Targeting isoaspartate-modified A beta rescues behavioral deficits in transgenic mice with Alzheimer's disease-like pathology von Gnoth, Kathrin, Piechotta, Anke, Kleinschmidt, Martin, Konrath, Sandra, Schenk, Mathias, Taudte, Nadine, Ramsbeck, Daniel, Rieckmann, Vera, Geissler, Stefanie, Eichentopf, Rico, Barendrecht, Susan, Hartlage-Ruebsamen, Maike, Demuth, Hans-Ulrich, Rossner, Steffen, Cynis, Holger, Rahfeld, Jens-Ulrich, Schilling, Stephan

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Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice von Gnoth, Kathrin, Geissler, Stefanie, Feldhaus, Julia, Taudte, Nadine, Ilse, Victoria, Zürner, Sebastian, Greiser, Sebastian, Braumann, Ulf-Dietrich, Rahfeld, Jens-Ulrich, Cynis, Holger, Schilling, Stephan

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Isolation of an Isoenzyme of Human Glutaminyl Cyclase: Retention in the Golgi Complex Suggests Involvement in the Protein Maturation Machinery von Cynis, Holger, Rahfeld, Jens-Ulrich, Stephan, Anett, Kehlen, Astrid, Koch, Birgit, Wermann, Michael, Demuth, Hans-Ulrich, Schilling, Stephan

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