An ACE2 Triple Decoy that neutralizes SARS-CoV-2 shows enhanced affinity for virus variants von Tanaka, Shiho, Nelson, Gard, Olson, C. Anders, Buzko, Oleksandr, Higashide, Wendy, Shin, Annie, Gonzalez, Marcos, Taft, Justin, Patel, Roosheel, Buta, Sofija, Richardson, Ashley, Bogunovic, Dusan, Spilman, Patricia, Niazi, Kayvan, Rabizadeh, Shahrooz, Soon-Shiong, Patrick

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A deep learning image-based intrinsic molecular subtype classifier of breast tumors reveals tumor heterogeneity that may affect survival von Jaber, Mustafa I., Song, Bing, Taylor, Clive, Vaske, Charles J., Benz, Stephen C., Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Szeto, Christopher W.

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Intranasal plus subcutaneous prime vaccination with a dual antigen COVID-19 vaccine elicits T-cell and antibody responses in mice von Rice, Adrian, Verma, Mohit, Shin, Annie, Zakin, Lise, Sieling, Peter, Tanaka, Shiho, Balint, Joseph, Dinkins, Kyle, Adisetiyo, Helty, Morimoto, Brett, Higashide, Wendy, Anders Olson, C., Mody, Shivani, Spilman, Patricia, Gabitzsch, Elizabeth, Safrit, Jeffrey T., Rabizadeh, Shahrooz, Niazi, Kayvan, Soon-Shiong, Patrick

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Stable transplantation of human mitochondrial DNA by high-throughput, pressurized isolated mitochondrial delivery von Sercel, Alexander J., Patananan, Alexander N., Man, Tianxing, Wu, Ting-Hsiang, Yu, Amy K., Guyot, Garret W., Rabizadeh, Shahrooz, Niazi, Kayvan R., Chiou, Pei-Yu, Teitell, Michael A.

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PD-L1 targeting high-affinity NK (t-haNK) cells induce direct antitumor effects and target suppressive MDSC populations von Fabian, Kellsye P, Padget, Michelle R, Donahue, Renee N., Solocinski, Kristen, Robbins, Yvette, Allen, Clint T., Lee, John H., Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Schlom, Jeffrey, Hodge, James W

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Label-free high-throughput cell screening in flow von Mahjoubfar, Ata, Chen, Claire, Niazi, Kayvan R, Rabizadeh, Shahrooz, Jalali, Bahram

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Overcoming hypoxia-induced functional suppression of NK cells von Solocinski, Kristen, Padget, Michelle R, Fabian, Kellsye P, Wolfson, Benjamin, Cecchi, Fabiola, Hembrough, Todd, Benz, Stephen C, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Schlom, Jeffrey, Hodge, James W

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Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling von Dave, Bhuvanesh, Granados-Principal, Sergio, Zhu, Rui, Benz, Stephen, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Yu, Ke-Da, Shao, Zhimin, Li, Xiaoxian, Gilcrease, Michael, Lai, Zhao, Chen, Yidong, Huang, Tim H.-M., Shen, Haifa, Liu, Xuewu, Ferrari, Mauro, Zhan, Ming, Wong, Stephen T. C., Kumaraswami, Muthiah, Mittal, Vivek, Chen, Xi, Gross, Steven S., Chang, Jenny C.

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Immunotherapy utilizing the combination of natural killer- and antibody dependent cellular cytotoxicity (ADCC)-mediating agents with poly (ADP-ribose) polymerase (PARP) inhibition von Fenerty, Kathleen E, Padget, Michelle, Wolfson, Benjamin, Gameiro, Sofia R, Su, Zhen, Lee, John H, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Hodge, James W

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Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display von Tanaka, Shiho, Olson, C. Anders, Barnes, Christopher O., Higashide, Wendy, Gonzalez, Marcos, Taft, Justin, Richardson, Ashley, Martin-Fernandez, Marta, Bogunovic, Dusan, Gnanapragasam, Priyanthi N.P., Bjorkman, Pamela J., Spilman, Patricia, Niazi, Kayvan, Rabizadeh, Shahrooz, Soon-Shiong, Patrick

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1373 SynBAd, a clinical cancer vaccine candidate, induces antigen-specific T cells and extends life in a therapeutic liver cancer model von Niazi, Kayvan R, Sieling, Peter A, Rabizadeh, Shahrooz, Benz, Steve, Golovato, Justin, Nolasco, Aleece

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1374 Virus-like DNA, a single-agent poly-functional therapeutic platform that potently activates anti-cancer protective immunity von Niazi, Kayvan R, Sieling, Peter A, Benz, Steve, Golovato, Justin, Rabizadeh, Shahrooz

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Dual-Antigen COVID-19 Vaccine Subcutaneous Prime Delivery With Oral Boosts Protects NHP Against SARS-CoV-2 Challenge von Gabitzsch, Elizabeth, Safrit, Jeffrey T., Verma, Mohit, Rice, Adrian, Sieling, Peter, Zakin, Lise, Shin, Annie, Morimoto, Brett, Adisetiyo, Helty, Wong, Raymond, Bezawada, Ashish, Dinkins, Kyle, Balint, Joseph, Peykov, Victor, Garban, Hermes, Liu, Philip, Bacon, Andrew, Bone, Pete, Drew, Jeff, Sanford, Daniel C., Spilman, Patricia, Sender, Lennie, Rabizadeh, Shahrooz, Niazi, Kayvan, Soon-Shiong, Patrick

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Phase I study of a multitargeted recombinant Ad5 PSA/MUC-1/brachyury-based immunotherapy vaccine in patients with metastatic castration-resistant prostate cancer (mCRPC) von Bilusic, Marijo, McMahon, Sheri, Madan, Ravi A, Karzai, Fatima, Tsai, Yo-Ting, Donahue, Renee N, Palena, Claudia, Jochems, Caroline, Marté, Jennifer L, Floudas, Charalampos, Strauss, Julius, Redman, Jason, Abdul Sater, Houssein, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Schlom, Jeffrey, Gulley, James L

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The multi-functionality of N-809, a novel fusion protein encompassing anti-PD-L1 and the IL-15 superagonist fusion complex von Jochems, Caroline, Tritsch, Sarah R., Knudson, Karin M., Gameiro, Sofia R., Rumfield, Claire Smalley, Pellom, Samuel T., Morillon, Y. Maurice, Newman, Robby, Marcus, Warren, Szeto, Christopher, Rabizadeh, Shahrooz, Wong, Hing C., Soon-Shiong, Patrick, Schlom, Jeffrey

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Single-cell sequencing and tumorigenesis: improved understanding of tumor evolution and metastasis von Ellsworth, Darrell L., Blackburn, Heather L., Shriver, Craig D., Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Ellsworth, Rachel E.

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Identification of a Novel Ras-Regulated Proapoptotic Pathway von Khokhlatchev, Andrei, Rabizadeh, Shahrooz, Xavier, Ramnik, Nedwidek, Maria, Chen, Tao, Zhang, Xian-feng, Seed, Brian, Avruch, Joseph

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Vault nanocapsules as adjuvants favor cell-mediated over antibody-mediated immune responses following immunization of mice von Kar, Upendra K, Jiang, Janina, Champion, Cheryl I, Salehi, Sahar, Srivastava, Minu, Sharma, Sherven, Rabizadeh, Shahrooz, Niazi, Kayvan, Kickhoefer, Valerie, Rome, Leonard H, Kelly, Kathleen A

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Deep Learning Implicitly Handles Tissue Specific Phenomena to Predict Tumor DNA Accessibility and Immune Activity von Wnuk, Kamil, Sudol, Jeremi, Givechian, Kevin B., Soon-Shiong, Patrick, Rabizadeh, Shahrooz, Szeto, Christopher, Vaske, Charles

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Identification and validation of expressed HLA-binding breast cancer neoepitopes for potential use in individualized cancer therapy von Reimann, Hannah, Nguyen, Andrew, Sanborn, J Zachary, Vaske, Charles J, Benz, Stephen C, Niazi, Kayvan, Rabizadeh, Shahrooz, Spilman, Patricia, Mackensen, Andreas, Ruebner, Matthias, Hein, Alexander, Beckmann, Matthias W, van der Meijden, Edith D, Bausenwein, Judith, Kretschmann, Sascha, Griffioen, Marieke, Schlom, Jeffrey, Gulley, James L, Lee, Karin L, Hamilton, Duane H, Soon-Shiong, Patrick, Fasching, Peter A, Kremer, Anita N.

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