DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets von Hanaford, Allison R, Archer, Tenley C, Price, Antoinette, Kahlert, Ulf D, Maciaczyk, Jarek, Nikkhah, Guido, Kim, Jong Wook, Ehrenberger, Tobias, Clemons, Paul A, Dančík, Vlado, Seashore-Ludlow, Brinton, Viswanathan, Vasanthi, Stewart, Michelle L, Rees, Matthew G, Shamji, Alykhan, Schreiber, Stuart, Fraenkel, Ernest, Pomeroy, Scott L, Mesirov, Jill P, Tamayo, Pablo, Eberhart, Charles G, Raabe, Eric H

Volltext

OFFICE SPACE DIVIDING SYSTEM von BOUSE, JAMES R, NIEBOER, WILLIAM L, RAABE, CHARLES G, CONNER, JOHN P, DELONG, RONALD B

Volltext bestellen

OFFICE SPACE DIVIDING SYSTEM von NIEBOER, WILLIAM L, RAABE, CHARLES G, CONNER, JOHN P, DELONG, RONALD B, BOUSE, JAMES R

Volltext bestellen

SPACE DIVIDING PARTITION SYSTEM HAVING AN ELECTRICAL RACEWAY von HOLLERBACH, ERIC T, CYKANA, DANIEL, BRUGGINK, BRADLEY J, PERSING, BRIAN J, RAABE, CHARLES G, BEMIS, PETER F, DELONG, RONALD B, BOUSE, JAMES R

Volltext bestellen

SPACE DIVIDING PARTITION SYSTEM HAVING AN ELECTRICAL RACEWAY von BEMIS, PETER F, HOLLERBACH, ERIC T, BOUSE, JAMES R, RAABE, CHARLES G, BRUGGINK, BRADLEY J, CYKANA, DANIEL, DELONG, RONALD B, PERSING, BRIAN J

Volltext bestellen

ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner von Brosnan-Cashman, Jacqueline A, Yuan, Ming, Graham, Mindy K, Rizzo, Anthony J, Myers, Kaylar M, Davis, Christine, Zhang, Rebecca, Esopi, David M, Raabe, Eric H, Eberhart, Charles G, Heaphy, Christopher M, Meeker, Alan K

Volltext

Synergistic activity of mTORC1/2 kinase and MEK inhibitors suppresses pediatric low-grade glioma tumorigenicity and vascularity von Arnold, Antje, Yuan, Ming, Price, Antionette, Harris, Lauren, Eberhart, Charles G, Raabe, Eric H

Volltext

The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma von Miyahara, Hiroaki, Yadavilli, Sridevi, Natsumeda, Manabu, Rubens, Jeffrey, Rodgers, Louis, Kambhampati, Madhuri, Taylor, Isabella, Kaur, Harpreet, Asnaghi, Laura, Eberhart, Charles G, Warren, Katherine E, Nazarian, Javad, Raabe, Eric H

Volltext

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma von Grasso, Catherine S, Tang, Yujie, Truffaux, Nathalene, Berlow, Noah E, Liu, Lining, Debily, Marie-Anne, Quist, Michael J, Davis, Lara E, Huang, Elaine C, Woo, Pamelyn J, Ponnuswami, Anitha, Chen, Spenser, Johung, Tessa B, Sun, Wenchao, Kogiso, Mari, Du, Yuchen, Qi, Lin, Huang, Yulun, Hütt-Cabezas, Marianne, Warren, Katherine E, Le Dret, Ludivine, Meltzer, Paul S, Mao, Hua, Quezado, Martha, van Vuurden, Dannis G, Abraham, Jinu, Fouladi, Maryam, Svalina, Matthew N, Wang, Nicholas, Hawkins, Cynthia, Nazarian, Javad, Alonso, Marta M, Raabe, Eric H, Hulleman, Esther, Spellman, Paul T, Li, Xiao-Nan, Keller, Charles, Pal, Ranadip, Grill, Jacques, Monje, Michelle

Volltext

Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma von Hanaford, Allison R., Alt, Jesse, Rais, Rana, Wang, Sabrina Z., Kaur, Harpreet, Thorek, Daniel L.J., Eberhart, Charles G., Slusher, Barbara S., Martin, Allison M., Raabe, Eric H.

Volltext

ZEB1 Promotes Invasion in Human Fetal Neural Stem Cells and Hypoxic Glioma Neurospheres von Kahlert, Ulf D., Suwala, Abigail K., Raabe, Eric H., Siebzehnrubl, Florian A., Suarez, Maria J., Orr, Brent A., Bar, Eli E., Maciaczyk, Jaroslaw, Eberhart, Charles G.

Volltext

Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells von Kahlert, Ulf D., Cheng, Menglin, Koch, Katharina, Marchionni, Luigi, Fan, Xing, Raabe, Eric H., Maciaczyk, Jarek, Glunde, Kristine, Eberhart, Charles G.

Volltext

PD-L1 expression in medulloblastoma: an evaluation by subgroup von Martin, Allison M, Nirschl, Christopher J, Polanczyk, Magda J, Bell, W Robert, Nirschl, Thomas R, Harris-Bookman, Sarah, Phallen, Jillian, Hicks, Jessica, Martinez, Daniel, Ogurtsova, Aleksandra, Xu, Haiying, Sullivan, Lisa M, Meeker, Alan K, Raabe, Eric H, Cohen, Kenneth J, Eberhart, Charles G, Burger, Peter C, Santi, Mariarita, Taube, Janis M, Pardoll, Drew M, Drake, Charles G, Lim, Michael

Volltext

Novel Glutamine Antagonist JHU395 Suppresses MYC-Driven Medulloblastoma Growth and Induces Apoptosis von Pham, Khoa, Maxwell, Micah J, Sweeney, Heather, Alt, Jesse, Rais, Rana, Eberhart, Charles G, Slusher, Barbara S, Raabe, Eric H

Volltext

Response to letter to the editor: “All models are wrong; some models are useful” von Arnold, Antje, Rodriguez, Fausto, Eberhart, Charles G, Raabe, Eric H

Volltext

Inhibition of enhancer of zest homologue 2 is a potential therapeutic target for high‐MYC medulloblastoma von Natsumeda, Manabu, Liu, Yang, Nakata, Satoshi, Miyahara, Hiroaki, Hanaford, Allison, Ahsan, Sama, Stearns, Duncan, Skuli, Nicolas, Kahlert, Ulf D., Raabe, Eric H., Rodriguez, Fausto J., Eberhart, Charles G.

Volltext

MEK Inhibition Suppresses Growth of Atypical Teratoid/Rhabdoid Tumors von Shahab, Shubin, Rubens, Jeffrey, Kaur, Harpreet, Sweeney, Heather, Eberhart, Charles G, Raabe, Eric H

Volltext

BRAF Activation Induces Transformation and Then Senescence in Human Neural Stem Cells: A Pilocytic Astrocytoma Model von RAABE, Eric H, KAH SUAN LIM, COHEN, Kenneth J, EBERHART, Charles G, KIM, Julia M, MEEKER, Alan, MAO, Xing-Gang, NIKKHAH, Guido, MACIACZYK, Jarek, KAHLERT, Ulf, JAIN, Deepali, BAR, Eli

Volltext

Unbiased Metabolic Profiling Predicts Sensitivity of High MYC-Expressing Atypical Teratoid/Rhabdoid Tumors to Glutamine Inhibition with 6-Diazo-5-Oxo-L-Norleucine von Wang, Sabrina Z, Poore, Brad, Alt, Jesse, Price, Antoinette, Allen, Sariah J, Hanaford, Allison R, Kaur, Harpreet, Orr, Brent A, Slusher, Barbara S, Eberhart, Charles G, Raabe, Eric H, Rubens, Jeffrey A

Volltext

The transcriptional modulator HMGA2 promotes stemness and tumorigenicity in glioblastoma von Kaur, Harpreet, Ali, Sabeen Zulfiqar, Huey, Lauren, Hütt-Cabezas, Marianne, Taylor, Isabella, Mao, Xing-gang, Weingart, Melanie, Chu, Qian, Rodriguez, Fausto J, Eberhart, Charles G, Raabe, Eric H

Volltext