Key discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decades von Hofmann, Alan F., Hagey, Lee R.

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Bile salts of vertebrates: structural variation and possible evolutionary significance[S] von Hofmann, Alan F., Hagey, Lee R., Krasowski, Matthew D.

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Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis von Tabibian, James H., O'Hara, Steven P., Trussoni, Christy E., Tietz, Pamela S., Splinter, Patrick L., Mounajjed, Taofic, Hagey, Lee R., LaRusso, Nicholas F.

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MAFG Is a Transcriptional Repressor of Bile Acid Synthesis and Metabolism von de Aguiar Vallim, Thomas Q., Tarling, Elizabeth J., Ahn, Hannah, Hagey, Lee R., Romanoski, Casey E., Lee, Richard G., Graham, Mark J., Motohashi, Hozumi, Yamamoto, Masayuki, Edwards, Peter A.

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A “Forward Genomics” Approach Links Genotype to Phenotype using Independent Phenotypic Losses among Related Species von Hiller, Michael, Schaar, Bruce T., Indjeian, Vahan B., Kingsley, David M., Hagey, Lee R., Bejerano, Gill

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Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR von Krasowski, Matthew D., Ni, Ai, Hagey, Lee R., Ekins, Sean

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Diversity of Bile Salts in Fish and Amphibians: Evolution of a Complex Biochemical Pathway von Hagey, Lee R., Møller, Peter R., Hofmann, Alan F., Krasowski, Matthew D.

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The effect of dietary prebiotics and probiotics on body weight, large intestine indices, and fecal bile acid profile in wild type and IL10-/- mice von Kuo, Shiu-Ming, Merhige, Patricia M, Hagey, Lee R

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Human cecal bile acids: concentration and spectrum von Hamilton, James P, Xie, Guofeng, Raufman, Jean-Pierre, Hogan, Susan, Griffin, Terrance L, Packard, Christine A, Chatfield, Dale A, Hagey, Lee R, Steinbach, Joseph H, Hofmann, Alan F

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Evolution of pharmacologic specificity in the pregnane X receptor von Ekins, Sean, Reschly, Erica J, Hagey, Lee R, Krasowski, Matthew D

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Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine von Weerachayaphorn, Jittima, Mennone, Albert, Soroka, Carol J, Harry, Kathy, Hagey, Lee R, Kensler, Thomas W, Boyer, James L

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Na+/H+ exchanger regulatory factor 1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injury von Li, Man, Mennone, Albert, Soroka, Carol J., Hagey, Lee R., Ouyang, Xinshou, Weinman, Edward J., Boyer, James L.

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Evolutionary diversity of bile salts in reptiles and mammals, including analysis of ancient human and extinct giant ground sloth coprolites von Hagey, Lee R, Vidal, Nicolas, Hofmann, Alan F, Krasowski, Matthew D

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The changing metabolic landscape of bile acids – keys to metabolism and immune regulation von Mohanty, Ipsita, Allaband, Celeste, Mannochio-Russo, Helena, El Abiead, Yasin, Hagey, Lee R., Knight, Rob, Dorrestein, Pieter C.

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Functional evolution of the vitamin D and pregnane X receptors von Reschly, Erica J, Bainy, Afonso Celso Dias, Mattos, Jaco Joaquim, Hagey, Lee R, Bahary, Nathan, Mada, Sripal R, Ou, Junhai, Venkataramanan, Raman, Krasowski, Matthew D

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Evolution of the bile salt nuclear receptor FXR in vertebrates von Reschly, Erica J, Ai, Ni, Ekins, Sean, Welsh, William J, Hagey, Lee R, Hofmann, Alan F, Krasowski, Matthew D

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How bile acids and the microbiota interact to shape host immunity von Lee, Michael H., Nuccio, Sean-Paul, Mohanty, Ipsita, Hagey, Lee R., Dorrestein, Pieter C., Chu, Hiutung, Raffatellu, Manuela

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Sirtuin 1 activation alleviates cholestatic liver injury in a cholic acid–fed mouse model of cholestasis von Kulkarni, Supriya R., Soroka, Carol J., Hagey, Lee R., Boyer, James L.

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The underappreciated diversity of bile acid modifications von Mohanty, Ipsita, Mannochio-Russo, Helena, Schweer, Joshua V., El Abiead, Yasin, Bittremieux, Wout, Xing, Shipei, Schmid, Robin, Zuffa, Simone, Vasquez, Felipe, Muti, Valentina B., Zemlin, Jasmine, Tovar-Herrera, Omar E., Moraïs, Sarah, Desai, Dhimant, Amin, Shantu, Koo, Imhoi, Turck, Christoph W., Mizrahi, Itzhak, Kris-Etherton, Penny M., Petersen, Kristina S., Fleming, Jennifer A., Huan, Tao, Patterson, Andrew D., Siegel, Dionicio, Hagey, Lee R., Wang, Mingxun, Aron, Allegra T., Dorrestein, Pieter C.

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In memoriam: the maestro of bile acids: Alan F. Hofmann (1931–2021) von Dawson, Paul A., Hagey, Lee R., Roda, Aldo

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