Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective von Kenna, J. Gerry, Taskar, Kunal S., Battista, Christina, Bourdet, David L., Brouwer, Kim L.R., Brouwer, Kenneth R., Dai, David, Funk, Christoph, Hafey, Michael J., Lai, Yurong, Maher, Jonathan, Pak, Y. Anne, Pedersen, Jenny M., Polli, Joseph W., Rodrigues, A. David, Watkins, Paul B., Yang, Kyunghee, Yucha, Robert W.

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Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis von Ferslew, Brian C., Xie, Guoxiang, Johnston, Curtis K., Su, Mingming, Stewart, Paul W., Jia, Wei, Brouwer, Kim L. R., Sidney Barritt, A.

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Prediction of Altered Bile Acid Disposition Due to Inhibition of Multiple Transporters: An Integrated Approach Using Sandwich-Cultured Hepatocytes, Mechanistic Modeling, and Simula... von Guo, Cen, Yang, Kyunghee, Brouwer, Kenneth R, St Claire, 3rd, Robert L, Brouwer, Kim L R

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A universal deep neural network for in-depth cleaning of single-cell RNA-Seq data von Li, Hui, Brouwer, Cory R., Luo, Weijun

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LinkageMapView-rendering high-resolution linkage and QTL maps von Ouellette, Lisa A, Reid, Robert W, Blanchard, Steven G, Brouwer, Cory R

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Inhibition of Human Hepatic Bile Acid Transporters by Tolvaptan and Metabolites: Contributing Factors to Drug-Induced Liver Injury? von Slizgi, Jason R, Lu, Yang, Brouwer, Kenneth R, St Claire, Robert L, Freeman, Kimberly M, Pan, Maxwell, Brock, William J, Brouwer, Kim L R

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Farnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and Mechanisms von Guo, Cen, LaCerte, Carl, Edwards, Jeffrey E, Brouwer, Kenneth R, Brouwer, Kim L R

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Lipidomics profiles in hepatocytes from nonalcoholic steatohepatitis patients differ markedly from in vitro‐induced steatotic hepatocytes von Kralj, Thomas, Khatri, Raju, Brouwer, Kenneth R., Brouwer, Kim L. R., Creek, Darren J.

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Developing evidence-based resources for evaluating postgraduate trainees in the biomedical sciences von McLaughlin, Jacqueline E, Layton, Rebekah L, Watkins, Paul B, Nicholas, Robert A, Brouwer, Kim L R

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Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver von Chu, X, Korzekwa, K, Elsby, R, Fenner, K, Galetin, A, Lai, Y, Matsson, P, Moss, A, Nagar, S, Rosania, G R, Bai, J P F, Polli, J W, Sugiyama, Y, Brouwer, K L R

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Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cult... von Pfeifer, Nathan D, Yang, Kyunghee, Brouwer, Kim L R

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A Perspective on Efflux Transport Proteins in the Liver von Köck, K, Brouwer, K L R

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In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development von Brouwer, K L R, Keppler, D, Hoffmaster, K A, Bow, D A J, Cheng, Y, Lai, Y, Palm, J E, Stieger, B, Evers, R

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Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4 von Köck, Kathleen, Ferslew, Brian C, Netterberg, Ida, Yang, Kyunghee, Urban, Thomas J, Swaan, Peter W, Stewart, Paul W, Brouwer, Kim L R

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Can they imagine the future? A qualitative study exploring the skills employers seek in pharmaceutical sciences doctoral graduates von McLaughlin, Jacqueline E, Minshew, Lana M, Gonzalez, Daniel, Lamb, Kelsey, Klus, Nicholas J, Aubé, Jeffrey, Cox, Wendy, Brouwer, Kim L R

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Key Role for the 12-Hydroxy Group in the Negative Ion Fragmentation of Unconjugated C24 Bile Acids von Lan, Ke, Su, Mingming, Xie, Guoxiang, Ferslew, Brian C, Brouwer, Kim L.R, Rajani, Cynthia, Liu, Changxiao, Jia, Wei

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“A convenient truth”: air travel passengers' willingness to pay to offset their CO₂ emissions von Brouwer, R, Brander, L, Van Beukering, P

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From principles to practice in paying for nature’s services von Wunder, S., Brouwer, R., Engel, S., Ezzine-de-Blas, D., Muradian, R., Pascual, U., Pinto, R.

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Comparison of Closing-Wedge and Opening-Wedge High Tibial Osteotomy for Medial Compartment Osteoarthritis of the Knee: A Randomized Controlled Trial with a Six-Year Follow-up von Duivenvoorden, T, Brouwer, R.W, Baan, A, Bos, P.K, Reijman, M, Bierma-Zeinstra, S.M.A, Verhaar, J.A.N

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A novel differentiated HuH-7 cell model to examine bile acid metabolism, transport and cholestatic hepatotoxicity von Saran, Chitra, Fu, Dong, Ho, Henry, Klein, Abigail, Fallon, John K., Honkakoski, Paavo, Brouwer, Kim L. R.

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