PRDM16 controls a brown fat/skeletal muscle switch von Seale, Patrick, Bjork, Bryan, Yang, Wenli, Kajimura, Shingo, Chin, Sherry, Kuang, Shihuan, Scimè, Anthony, Devarakonda, Srikripa, Conroe, Heather M, Erdjument-Bromage, Hediye

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Estimating the selective effects of heterozygous protein-truncating variants from human exome data von Cassa, Christopher A, Weghorn, Donate, Balick, Daniel J, Jordan, Daniel M, Nusinow, David, Samocha, Kaitlin E, O'Donnell-Luria, Anne, MacArthur, Daniel G, Daly, Mark J, Beier, David R, Sunyaev, Shamil R

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Differential requirements of tubulin genes in mammalian forebrain development von Bittermann, Elizabeth, Abdelhamed, Zakia, Liegel, Ryan P, Menke, Chelsea, Timms, Andrew, Beier, David R, Stottmann, Rolf W

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NEK8 Links the ATR-Regulated Replication Stress Response and S Phase CDK Activity to Renal Ciliopathies von Choi, Hyo Jei Claudia, Lin, Jia-Ren, Vannier, Jean-Baptiste, Slaats, Gisela G., Kile, Andrew C., Paulsen, Renee D., Manning, Danielle K., Beier, David R., Giles, Rachel H., Boulton, Simon J., Cimprich, Karlene A.

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Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease von Pooler, Amy M, Polydoro, Manuela, Maury, Eduardo A, Nicholls, Samantha B, Reddy, Snigdha M, Wegmann, Susanne, William, Christopher, Saqran, Lubna, Cagsal-Getkin, Ozge, Pitstick, Rose, Beier, David R, Carlson, George A, Spires-Jones, Tara L, Hyman, Bradley T

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Mutation mapping and identification by whole-genome sequencing von Leshchiner, Ignaty, Alexa, Kristen, Kelsey, Peter, Adzhubei, Ivan, Austin-Tse, Christina A, Cooney, Jeffrey D, Anderson, Heidi, King, Matthew J, Stottmann, Rolf W, Garnaas, Maija K, Ha, Seungshin, Drummond, Iain A, Paw, Barry H, North, Trista E, Beier, David R, Goessling, Wolfram, Sunyaev, Shamil R

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Loss of function of Colgalt1 disrupts collagen post-translational modification and causes musculoskeletal defects von Geister, Krista A, Lopez-Jimenez, Alberto Jose, Houghtaling, Scott, Ho, Tzu-Hua, Vanacore, Roberto, Beier, David R

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Inv acts as a molecular anchor for Nphp3 and Nek8 in the proximal segment of primary cilia von Shiba, Dai, Manning, Danielle K., Koga, Hisashi, Beier, David R., Yokoyama, Takahiko

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zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch von Hellman, Nathan E, Liu, Yan, Merkel, Erin, Austin, Christina, Le Corre, Stephanie, Beier, David R, Sun, Zhaoxia, Sharma, Neeraj, Yoder, Bradley K, Drummond, Iain A

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TAT-mediated PRDX6 protein transduction protects against eye lens epithelial cell death and delays lens opacity von Kubo, Eri, Fatma, Nigar, Akagi, Yoshio, Beier, David R, Singh, Sanjay P, Singh, Dhirendra P

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Optimizing Genomic Methods for Mapping and Identification of Candidate Variants in ENU Mutagenesis Screens Using Inbred Mice von Geister, Krista A, Timms, Andrew E, Beier, David R

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Nek8 Regulates the Expression and Localization of Polycystin-1 and Polycystin-2 von SOHARA, Eisei, YING LUO, JINGJING ZHANG, MANNING, Danielle K, BEIER, David R, JING ZHOU

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ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning von Czarnecki, Peter G., Gabriel, George C., Manning, Danielle K., Sergeev, Mikhail, Lemke, Kristi, Klena, Nikolai T., Liu, Xiaoqin, Chen, Yu, Li, You, San Agustin, Jovenal T., Garnaas, Maija K., Francis, Richard J., Tobita, Kimimasa, Goessling, Wolfram, Pazour, Gregory J., Lo, Cecilia W., Beier, David R., Shah, Jagesh V.

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Loss of the Ciliary Kinase Nek8 Causes Left-Right Asymmetry Defects von MANNING, Danielle K, SERGEEV, Mikhail, HEESBEEN, Roy G. Van, WONG, Michael D, OH, Jin-Hee, YAN LIU, MARK HENKELMAN, R, DRUMMOND, Lain, SHAH, Jagesh V, BEIER, David R

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Mutations in Dnaaf1 and Lrrc48 Cause Hydrocephalus, Laterality Defects, and Sinusitis in Mice von Ha, Seungshin, Lindsay, Anna M, Timms, Andrew E, Beier, David R

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Impaired Organic Anion Transport in Kidney and Choroid Plexus of Organic Anion Transporter 3 (Oat3 (Slc22a8)) Knockout Mice von Sweet, Douglas H., Miller, David S., Pritchard, John B., Fujiwara, Yuko, Beier, David R., Nigam, Sanjay K.

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Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo von Stottmann, Rolf W, Turbe-Doan, Annick, Tran, Pamela, Kratz, Lisa E, Moran, Jennifer L, Kelley, Richard I, Beier, David R

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Improvement of ENU Mutagenesis Efficiency Using Serial Injection and Mismatch Repair Deficiency Mice von Gallego-Llamas, Jabier, Timms, Andrew E, Pitstick, Rose, Peters, Janet, Carlson, George A, Beier, David R

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Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis von Okamura, Daryl M., Brewer, Chris M., Wakenight, Paul, Bahrami, Nadia, Bernardi, Kristina, Tran, Amy, Olson, Jill, Shi, Xiaogang, Yeh, Szu-Ying, Piliponsky, Adrian, Collins, Sarah J., Nguyen, Elizabeth D., Timms, Andrew E., MacDonald, James W., Bammler, Theo K., Nelson, Branden R., Millen, Kathleen J., Beier, David R., Majesky, Mark W.

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Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease von Hou, Xiaoying, Mrug, Michal, Yoder, Bradley K, Lefkowitz, Elliot J, Kremmidiotis, Gabriel, D'Eustachio, Peter, Beier, David R, Guay-Woodford, Lisa M

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