17β-Estradiol modulates local cardiac renin-angiotensin system to prevent cardiac remodeling in the DOCA-salt model of hypertension in rats von Shenoy, V., Grobe, J.L., Qi, Y., Ferreira, A.J., Fraga-Silva, R.A., Collamat, G., Bruce, E., Katovich, M.J.

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The Angiotensin-Converting Enzyme 2/Angiotensin-(1–7)/Mas receptor axis: A potential target for treating thrombotic diseases von Fraga-Silva, Rodrigo A., Da Silva, Danielle G., Montecucco, Fabrizio, Mach, François, Stergiopulos, Nikolaos, da Silva, Rafaela F., Santos, Robson A. S.

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Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice von Nencioni, Alessio, da Silva, Rafaela F., Fraga-Silva, Rodrigo A., Steffens, Sabine, Fabre, Mathias, Bauer, Inga, Caffa, Irene, Magnone, Mirko, Sociali, Giovanna, Quercioli, Alessandra, Pelli, Graziano, Lenglet, Sébastien, Galan, Katia, Burger, Fabienne, Calvo, Sara Vázquez, Bertolotto, Maria, Bruzzone, Santina, Ballestrero, Alberto, Patrone, Franco, Dallegri, Franco, Santos, Robson A. S., Stergiopulos, Nikolaos, Mach, François, Vuilleumier, Nicolas, Montecucco, Fabrizio

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390 Characterization of the Renin-Angiotensin System Regulation in Cavernosal Tissue of Aged Rats von Bragina, M.E., Fraga-Silva, R.A., Costa-Fraga, F.P., Stergiopulos, N.

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O043 Treatment with chemokine-binding protein Evasin-3 reduces atherosclerotic vulnerability for ischemic stroke in mice von Montecucco, F., da Silva, R., Fraga-Silva, R.A., Capettini, L., Quintao, S., Lenglet, S., Pelli, G., Galan, K., Braunersreuther, V., Schaller, K., Proudfoot, A.E., Stergiopulos, N., Santos, R.A., Gasche, Y., Mach, F., Copin, J.-C.

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Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice von A. Nencioni, R. F. da Silva, R. A. Fraga-Silva, S. Steffens, M. Fabre, I. Bauer, I. Caffa, M. Magnone, G. Sociali, A. Quercioli, G. Pelli, S. Lenglet, K. Galan, F. Burger, S. Vázquez Calvo, M. Bertolotto, S. Bruzzone, A. Ballestrero, F. Patrone, F. Dallegri, R. A. S. Santos, N. Stergiopulos, F. Mach, N. Vuilleumier, F. Montecucco

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Poster session 3Cell growth, differentiation and stem cells - Heart511The role of the endocannabinoid system in modelling muscular dystrophy cardiac disease with induced pluripoten... von Gowran, A, Kulikova, T, Lewis, FC, Foldes, G, Fuentes, L, Viiri, LE, Spinelli, V, Costa, A, Perbellini, F, Sid-Otmane, C, Bax, NAM, Pekkanen-Mattila, M, Schiano, C, Chaloupka, A, Forini, F, Sarkozy, M, De Jager, SCA, Vajen, T, Glezeva, N, Lee, H W, Golovkin, A, Kucera, T, Musikhina, NA, Korzhenkov, NP, Santuchi, M DE C, Munteanu, D, Garcia, RG, Ang, R, Usui, S, Kamilova, U, Jumeau, C, Aberg, M, Kostina, DA, Brandt, MM, Muntean, D, Lindner, D, Sadaba, R, Bacova, B, Nikolov, A, Sedmera, D, Ryabov, V, Neto, FP, Lynch, M, Portero, V, Kui, P, Howarth, FC, Gualdoni, A, Prorok, J, Diolaiuti, L, Vostarek, F, Wagner, M, Abela, MA, Nebert, C, Xiang, W, Kloza, M, Maslenko, A, Grechanyk, M, Bhattachariya, A, Morawietz, H, Babaeva, AR, Martinez Sanchez, SM, Krychtiuk, KA, Starodubova, J, Fiorelli, S, Rinne, P, Ozkaramanli Gur, D, Hofbauer, T, Stellos, K, Pinon, P, Tsoref, O, Thaler, B, Fraga-Silva, RA, Fuijkschot, WW, Shaaban, MNS, Matthaeus, C, Deluyker, D, Scardigli, M, Zahradnikova, A, Dominguez, A, Kondrat'eva, D, Sosorburam, T, Murarikova, M, Duerr, GD, Griecsova, L, Portnichenko, VI, Smolina, N, Duicu, OANA M, Elder, JM, Zaglia, T, Lorenzon, A, Ruperez, C, Woudstra, L, Suffee, N, De Lucia, C, Russell-Hallinan, A, Menendez-Montes, I, Kapelko, VI, Emmens, RW, Hetman, O, Van Der Laarse, WJ

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XNT, A SYNTHETIC ACE2 ACTIVATOR, IMPROVES ENDOTHELIAL FUNCTION: 1D.03 von Fraga-Silva, RA, Costa-Fraga, FP, Shenoy, V, Collamat, G, Katovich, MJ, Ferreira, AJ, Raizada, MK

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17beta-Estradiol modulates local cardiac renin-angiotensin system to prevent cardiac remodeling in the DOCA-salt model of hypertension in rats von Shenoy, V, Grobe, J L, Qi, Y, Ferreira, A J, Fraga-Silva, R A, Collamat, G, Bruce, E, Katovich, M J

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Effective Prevention of Carotid Artery Atherosclerosis by Following this Motto for Healthy Habits: “Give Up One, Reduce Two, and Increase Three” von Wada, T., Fujishiro, K., Fukumoto, T., Joki, M.

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Heparin prevents in vitro glycocalyx shedding induced by plasma from COVID-19 patients von Potje, Simone R., Costa, Tiago J., Fraga-Silva, Thais F.C., Martins, Ronaldo B., Benatti, Maira N., Almado, Carlos E.L., de Sá, Keyla S.G., Bonato, Vânia L.D., Arruda, Eurico, Louzada-Junior, Paulo, Oliveira, Rene D.R., Zamboni, Dario S., Becari, Christiane, Auxiliadora-Martins, Maria, Tostes, Rita C.

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Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage von Costa, Tiago J., Potje, Simone R., Fraga-Silva, Thais F.C., da Silva-Neto, Júlio A., Barros, Paula R., Rodrigues, Daniel, Machado, Mirele R., Martins, Ronaldo B., Santos-Eichler, Rosangela A., Benatti, Maira N., de Sá, Keyla S.G., Almado, Carlos Eduardo L., Castro, Ítalo A., Pontelli, Marjorie C., Serra, Leonardo La, Carneiro, Fernando S., Becari, Christiane, Louzada-Junior, Paulo, Oliveira, Rene D.R., Zamboni, Dario S., Arruda, Eurico, Auxiliadora-Martins, Maria, Giachini, Fernanda R.C., Bonato, Vânia L.D., Zachara, Natasha E., Bomfim, Gisele F., Tostes, Rita C.

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Apelin‐13 treatment enhances the stability of atherosclerotic plaques von Fraga‐Silva, Rodrigo A., Seeman, Hugo, Montecucco, Fabrizio, da Silva, Analina R., Burger, Fabienne, Costa‐Fraga, Fabiana P., Anguenot, Léa, Mach, François, dos Santos, Robson A. S., Stergiopulos, Nikolaos, da Silva, Rafaela F.

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Association of myelin peptide with vitamin D prevents autoimmune encephalomyelitis development von Mimura, L.A.N, Chiuso-Minicucci, F, Fraga-Silva, T.F.C, Zorzella-Pezavento, S.F.G, França, T.G.D, Ishikawa, L.L.W, Penitenti, M, Ikoma, M.R.V, Sartori, A

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Cytokine storm in individuals with severe COVID-19 decreases endothelial cell antioxidant defense via downregulation of the Nrf2 transcriptional factor von Rodrigues, Daniel, Machado, Mirele R, Alves, Juliano V, Fraga-Silva, Thais F C, Martins, Ronaldo B, Campos, Ligia C B, Francisco, Daniely F, Couto, Ariel E S, Bonato, Vânia L D, Arruda, Eurico, Becari, Christiane, Auxiliadora-Martins, Maria, Louzada-Júnior, Paulo, Costa, Rafael M, Tostes, Rita C

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Alpha 1-acid glycoprotein is upregulated in severe COVID-19 patients and decreases neutrophil NETs in SARS-CoV-2 infection von Mestriner, Fabiola, Francisco, Daniely F., Campos, Ligia C.B., Couto, Ariel E.S., Fraga-Silva, Thais F.C., Flora Dugaich, Vinicius, D Avila-Mesquita, Carolina, Zukowski Kovacs, Henrique, Vasconcelos, Jociany L., Milani, Elizabete R., Santos Guedes de Sá, Keyla, Martins, Ronaldo, Jordani, Maria C., Corsi, Carlos A.C., Barbosa, Jessyca M., Vasconcelos, Tauana, Gonçalves Menegueti, Mayra, Neto, Julio, da Costa, Rafael M., Evora, Paulo R.B., Arruda, Eurico, Tostes, Rita, Polonis, Katarzyna, Bonato, Vania L.D., Auxiliadora-Martins, Maria, Ribeiro, Mauricio S., Becari, Christiane

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Selenization of S. cerevisiae increases its protective potential in experimental autoimmune encephalomyelitis by triggering an intestinal immunomodulatory loop von de Campos Fraga-Silva, Thais Fernanda, Mimura, Luiza Ayumi Nishiyama, de Oliveira, Larissa Ragozo Cardoso, dos Santos Toledo, Juliana Helena, Borim, Patrícia Aparecida, Zorzella-Pezavento, Sofia Fernanda Gonçalvez, Alonso, Diego Peres, Ribolla, Paulo Eduardo Martins, de Oliveira, Carlos Alberto Ferreira, da Fonseca, Denise Morais, Villablanca, Eduardo J., Sartori, Alexandrina

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Update on the role of angiotensin in the pathophysiology of coronary atherothrombosis von da Silva, Analina R., Fraga-Silva, Rodrigo A., Stergiopulos, Nikolaos, Montecucco, Fabrizio, Mach, François

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Differential Behavior of Non- albicans Candida Species in the Central Nervous System of Immunocompetent and Immunosuppressed Mice von Sanches, Marcelo D'Alessandre, Mimura, Luiza A N, Oliveira, Larissa R C, Ishikawa, Larissa L W, Garces, Hans G, Bagagli, Eduardo, Sartori, Alexandrina, Kurokawa, Cilmery Suemi, Fraga-Silva, Thais F C

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Efferocytosis of SARS-CoV-2-infected dying cells impairs macrophage anti-inflammatory functions and clearance of apoptotic cells von Salina, Ana C G, Dos-Santos, Douglas, Rodrigues, Tamara S, Fortes-Rocha, Marlon, Freitas-Filho, Edismauro G, Alzamora-Terrel, Daniel L, Castro, Icaro M S, Fraga da Silva, Thais F C, de Lima, Mikhael H F, Nascimento, Daniele C, Silva, Camila M, Toller-Kawahisa, Juliana E, Becerra, Amanda, Oliveira, Samuel, Caetité, Diego B, Almeida, Leticia, Ishimoto, Adriene Y, Lima, Thais M, Martins, Ronaldo B, Veras, Flavio, do Amaral, Natália B, Giannini, Marcela C, Bonjorno, Letícia P, Lopes, Maria I F, Benatti, Maira N, Batah, Sabrina S, Santana, Rodrigo C, Vilar, Fernando C, Martins, Maria A, Assad, Rodrigo L, de Almeida, Sergio C L, de Oliveira, Fabiola R, Arruda Neto, Eurico, Cunha, Thiago M, Alves-Filho, José C, Bonato, Vania L D, Cunha, Fernando Q, Fabro, Alexandre T, Nakaya, Helder I, Zamboni, Dario S, Louzada-Junior, Paulo, Oliveira, Rene D R, Cunha, Larissa D

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