Oxidative stress and inflammation in the pathogenesis of activated polyamine catabolism-induced acute pancreatitis von Merentie, M, Uimari, A, Pietilä, M, Sinervirta, R, Keinänen, T. A, Vepsäläinen, J, Khomutov, A, Grigorenko, N, Herzig, K.-H, Jänne, J, Alhonen, L

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Acute Pancreatitis Induced by Activated Polyamine Catabolism Is Associated with Coagulopathy: Effects of α-Methylated Polyamine Analogs on Hemostasis von Hyvönen, M.T, Sinervirta, R, Keinänen, T.A, Fashe, T, Grigorenko, N, Khomutov, A.R, Vepsäläinen, J, Alhonen, L

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Gossypol Activates Pancreatic Polyamine Catabolism in Normal Rats and Induces Acute Pancreatitis in Transgenic Rats Over-expressing Spermidine/Spermine N 1 -Acetyltransferase von T.-L., Räsänen, L., Alhonen, R., Sinervirta, A., Uimari, K., Kaasinen, T., Keinänen, K.-H., Herzig, J., Jänne

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Transgenic mice aberrantly expressing human ornithine decarboxylase gene von HALMEKYTO, M, HYTTINEN, J.-M, JANNE, J, SINERVIRTA, R, UTRIAINEN, M, MYOHANEN, S, VOIPIO, H.-M, WAHLFORS, J, SYRJANEN, S, SYRJANEN, K, ALHONEN, L

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Activation of Polyamine Catabolism in Transgenic Rats Induces Acute Pancreatitis von Alhonen, Leena, Parkkinen, Jyrki J., Keinanen, Tuomo, Sinervirta, Riitta, Herzig, Karl-Heinz, Janne, Juhani

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Elevated Seizure Threshold and Impaired Spatial Learning in Transgenic Mice with Putrescine Overproduction in the Brain von Halonen, T., Sivenius, J., Miettinen, R., Halmekytö, M., Kauppinen, R., Sinervirta, R., Alakuijala, L., Alhonen, L., MacDonald, E., Jänne, J., Riekkinen Sr, P. J.

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Activated polyamine catabolism in acute pancreatitis : α-methylated polyamine analogues prevent trypsinogen activation and pancreatitis-associated mortality von HYVÖNEN, Mervi T, HERZIG, Karl-Heinz, KRÜGER, Burkhard, JÄNNE, Juhani, ALHONEN, Leena, SINERVIRTA, Riitta, ALBRECHT, Elke, NORDBACK, Isto, SAND, Juhani, KEINÄNEN, Tuomo A, VEPSÄLÄINEN, Jouko, GRIGORENKO, Nikolay, KHOMUTOV, Alex R

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A Polyamine Analogue Prevents Acute Pancreatitis and Restores Early Liver Regeneration in Transgenic Rats with Activated Polyamine Catabolism von Rasanen, Tiina-Liisa, Alhonen, Leena, Sinervirta, Riitta, Keinanen, Tuomo, Herzig, Karl-Heinz, Suppola, Suvikki, Khomutov, Alex R, Vepsalainen, Jouko, Janne, Juhani

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Metabolic Stability of α-Methylated Polyamine Derivatives and Their Use as Substitutes for the Natural Polyamines von Järvinen, Aki, Grigorenko, Nikolay, Khomutov, Alex R., Hyvönen, Mervi T., Uimari, Anne, Vepsäläinen, Jouko, Sinervirta, Riitta, Keinänen, Tuomo A., Vujcic, Slavoljub, Alhonen, Leena, Porter, Carl W., Jänne, Juhani

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Polyamines are required for the initiation of rat liver regeneration von Alhonen, Leena, Räsänen, Tiina-Liisa, Sinervirta, Riitta, Parkkinen, Jyrki J, Korhonen, Veli-Pekka, Pietilä, Marko, Jänne, Juhani

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Tissue-Specific Expression of Rat Light Neurofilament Promoter-Driven Reporter Gene in Transgenic Mice von Reeben, M., Halmekyto, M., Alhonen, L., Sinervirta, R., Saarma, M., Janne, J.

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Acute Pancreatitis Induced by Activated Polyamine Catabolism Is Associated with Coagulopathy: Effects of [alpha]-Methylated Polyamine Analogs on Hemostasis von Hyvönen, M T, Sinervirta, R, Keinänen, T A, Fashe, T, Grigorenko, N, Khomutov, A R, Vepsäläinen, J, Alhonen, L

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Characterization of a transgenic mouse line over-expressing the human ornithine decarboxylase gene von Halmekytö, M, Alhonen, L, Wahlfors, J, Sinervirta, R, Eloranta, T, Jänne, J

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α-Methyl Polyamines:  Efficient Synthesis and Tolerance Studies in Vivo and in Vitro. First Evidence for Dormant Stereospecificity of Polyamine Oxidase von Järvinen, Aki J, Cerrada-Gimenez, Marc, Grigorenko, Nikolay A, Khomutov, Alex R, Vepsäläinen, Jouko J, Sinervirta, Riitta M, Keinänen, Tuomo A, Alhonen, Leena I, Jänne, Juhani E

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Regulation of the expression of human ornithine decarboxylase gene and ornithine decarboxylase promoter-driven reporter gene in transgenic mice von HALMEKYTÖ, M, HYTTINEN, J.-M, SINERVIRTA, R, LEPPÄNEN, P, JÄNNE, J, ALHONEN, L

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Activated Polyamine Catabolism in Acute Pancreatitis: {alpha}-Methylated Polyamine Analogues Prevent Trypsinogen Activation and Pancreatitis-Associated Mortality von Hyvonen, Mervi T, Herzig, Karl-Heinz, Sinervirta, Riitta, Albrecht, Elke, Nordback, Isto, Sand, Juhani, Keinanen, Tuomo A, Vepsalainen, Jouko, Grigorenko, Nikolay, Khomutov, Alex R, Kruger, Burkhard, Janne, Juhani, Alhonen, Leena

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Cadaverine supplementation during a chronic exposure to difluoromethylornithine allows an overexpression, but prevents gene amplification, of ornithine decarboxylase in L1210 mouse... von Alhonen-Hongisto, L, Hirvonen, A, Sinervirta, R, Jänne, J

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Mouse and human ornithine decarboxylase genes. Methylation polymorphism and amplification von Alhonen-Hongisto, L, Leinonen, P, Sinervirta, R, Laine, R, Winqvist, R, Alitalo, K, Jänne, O A, Jänne, J

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Gene expression of ornithine decarboxylase in L1210 leukaemia cells exposed to DL-2-difluoromethylornithine in the presence of cadaverine von Alhonen-Hongisto, L, Sinervirta, R, Jänne, O A, Jänne, J

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S-adenosylmethionine decarboxylase from baker's yeast von Pösö, H, Sinervirta, R, Jänne, J

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