Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer von Lücking, Ulrich, Scholz, Arne, Lienau, Philip, Siemeister, Gerhard, Kosemund, Dirk, Bohlmann, Rolf, Briem, Hans, Terebesi, Ildiko, Meyer, Kirstin, Prelle, Katja, Denner, Karsten, Bömer, Ulf, Schäfer, Martina, Eis, Knut, Valencia, Ray, Ince, Stuart, von Nussbaum, Franz, Mumberg, Dominik, Ziegelbauer, Karl, Klebl, Bert, Choidas, Axel, Nussbaumer, Peter, Baumann, Matthias, Schultz‐Fademrecht, Carsten, Rühter, Gerd, Eickhoff, Jan, Brands, Michael

Volltext

Selective inhibitors of the FK506-binding protein 51 by induced fit von Gaali, Steffen, Kirschner, Alexander, Cuboni, Serena, Hartmann, Jakob, Kozany, Christian, Balsevich, Georgia, Namendorf, Christian, Fernandez-Vizarra, Paula, Sippel, Claudia, Zannas, Anthony S, Draenert, Rika, Binder, Elisabeth B, Almeida, Osborne F X, Rühter, Gerd, Uhr, Manfred, Schmidt, Mathias V, Touma, Chadi, Bracher, Andreas, Hausch, Felix

Volltext

Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties von Hartmann, Jakob, Wagner, Klaus V, Gaali, Steffen, Kirschner, Alexander, Kozany, Christian, Rühter, Gerd, Dedic, Nina, Häusl, Alexander S, Hoeijmakers, Lianne, Westerholz, Sören, Namendorf, Christian, Gerlach, Tamara, Uhr, Manfred, Chen, Alon, Deussing, Jan M, Holsboer, Florian, Hausch, Felix, Schmidt, Mathias V

Volltext

Abstract 4538: BAY 1112054, a highly selective, potent and orally available inhibitor of PTEFb/CDK9, shows convincing anti-tumor activity von Scholz, Arne, Lücking, Ulrich, Siemeister, Gerhard, Lienau, Philip, Eis, Knut, Wengner, Antje, Petersen, Kirstin, Bömer, Ulf, Nussbaumer, Peter, Choidas, Axel, Rühter, Gerd, Eickhoff, Jan, Schultz-Fademrecht, Carsten, Klebl, Bert, Ince, Stuart, Nussbaum, Franz von, Mumberg, Dominik, Brands, Michael, Ziegelbauer, Karl

Volltext

Palladium-Catalyzed Additions of Terminal Alkynes to Acceptor Alkynes von Trost, Barry M, Sorum, Mark T, Chan, Chuen, Rühter, Gerd

Volltext

Fragmentation of 1,3-dithiolane-derived sulfur ylides. A convenient thioaldehyde synthesis von Schaumann, Ernst, Rühter, Gerd

Volltext

Parallel Synthesis of Polyethylene Glycol Supported Biaryl Benzimidazoles and Imidazopyridines von Blettner, Carsten G., König, Wilfried A., Rühter, Gerd, Stenzel, Wolfgang, Schotten, Theo

Volltext

Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties von Hartmann, Jakob, Wagner, Klaus V, Gaali, Steffen, Kirschner, Alexander, Kozany, Christian, Ruhter, Gerd, Dedic, Nina, Hausl, Alexander S, Hoeijmakers, Lianne, Westerholz, Soren

Volltext

4-ARYL-N-PHENYL-1,3,5-TRIAZEN-2-AMINES CONTAINING A SULFOXIMINE GROUP von KOSEMUNG,DIRK, LIENAU, PHILIP, BOHLMANN, ROLF, SIEMEISTER, GERHARD, GNOTH MARK JEAN, SCHULTZ-FADEMRECHT, Carsten, SCHOLZ ARNE, BÖMER, ULF, LÜCKING, ULRIC, RÜHTER, GERD

Volltext bestellen

A Novel Route to Thiocarbonyl Compounds von Schaumann, Ernst, Wriede, Ulrich, Rühter, Gerd

Volltext

Fused Bicyclic Gly-Asp β-Turn Mimics with Specific Affinity for GPIIb-IIIa von Fisher, Matthew J, Arfstan, Ann E, Giese, Ulrich, Gunn, Bruce P, Harms, Cathy S, Khau, Vien, Kinnick, Michael D, Lindstrom, Terry D, Martinelli, Michael J, Mest, Hans-Jürgen, Mohr, Michael, Morin, John M, Mullaney, Jeffrey T, Nunes, Anne, Paal, Michael, Rapp, Achim, Rühter, Gerd, Ruterbories, Ken J, Sall, Daniel J, Scarborough, Robert M, Schotten, Theo, Sommer, Birgit, Stenzel, Wolfgang, Towner, Richard D, Um, Suzane L, Utterback, Barbara G, Vasileff, Robert T, Vöelkers, Silke, Wyss, Virginia L, Jakubowski, Joseph A

Volltext

PHARMACEUTICALLY ACTIVE DISUBSTITUTED TRIAZINE DERIVATIVES von LÜCKING, Ulrich, KLEBL, Bert, CHOIDAS, Axel, EICKHOFF, Jan, RÜHTER, Gerd, SCHULTZ-FADEMRECHT, Carsten, NUSSBAUMER, Peter

Volltext bestellen

Fused bicyclic Gly-asp β-turn mimics with potent affinity for GPIIb-IIIa. Exploration of the arginine isostere von FISHER, M. J, GIESE, U, RAPP, A, RÜHTER, G, RUTERBORIES, K. J, SALL, D. J, SCARBOROUGH, R. M, SCHOTTEN, T, STENZEL, W, TOWNER, R. D, UM, S. L, UTTERBACK, B. G, HARMS, C. S, WYSS, V. L, JAKUBOWSKI, J. A, KINNICK, M. D, LINDSTROM, T. D, MCCOWAN, J. R, MEST, H.-J, MORIN, J. M, MULLANEY, J. T, PAAL, M

Volltext

Compostos derivados de triazina dissubstituída farmaceuticamente ativos, composição farmacêutica, método para a síntese destes e uso dos mesmos von Eickhoff Jan, Nussbaumer Peter, Choidas Axel, Schultz-Fademrecht Carsten, Rühter Gerd, Lücking Ulrich, Klebl Bert

Volltext bestellen

Thioketone und Enthiolate durch 1,3‐anionische Cycloreversion von Dithiolan‐Derivaten von Schaumann, Ernst, Rühter, Gerd

Volltext

4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group von Lienau, Philip, Bömer, Ulf, Lücking, Ulrich, Scholz, Arne, Schultz-Fademrecht, Carsten, Bohlmann, Rolf, Rühter, Gerd, Siemeister, Gerhard, Kosemund, Dirk, Gnoth, Mark Jean

Volltext bestellen

4-ARYL-N-PHENYL-1,3,5-TRIAZIN-2-AMINES CONTAINING A SULFOXIMINE GROUP von LIENAU, PHILIP, BOHLMANN, ROLF, SCHOLZ, ARNE, LÜCKING, ULRICH, KOSEMUND, DIRK, BÖMER, ULF, RÜHTER, GERD, GNOTH, MARK, JEAN, FADEMRECHT, CARSTEN, SIEMEISTER,GERHARD

Volltext bestellen

Pharmaceutically active disubstituted pyridine derivatives von CHOIDAS AXEL, RÜHTER GERD, SCHULZ-FADEMRECHT CARSTEN, EICKHOFF JAN, NUSSBAUMER PETER, KLEBL BERT

Volltext bestellen

PHARMACEUTICALLY ACTIVE DISUBSTITUTED PYRIDINE DERIVATIVES von NUSSBAUMER, PETER, KLEBL, BERT, EICKHOFF, JAN, CHOIDAS, AXEL, RÜHTER, GERD, SCHULTZ-FADEMRECHT, CARSTEN

Volltext bestellen

Pharmaceutically active disubstituted triazine derivatives von RÜHTER GERD, SCHULZ-FADEMRECHT CARSTEN, KOCH UWE, EICKHOFF JAN, NUSSBAUMER PETER

Volltext bestellen