New Targeted Agents in Acute Myeloid Leukemia: New Hope on the Rise von Bohl, Stephan R, Bullinger, Lars, Rücker, Frank G

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Clinical implications of subclonal TP53 mutations in acute myeloid leukemia von Prochazka, Katharina T, Pregartner, Gudrun, Rücker, Frank G, Heitzer, Ellen, Pabst, Gabriel, Wölfler, Albert, Zebisch, Armin, Berghold, Andrea, Döhner, Konstanze, Sill, Heinz

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Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations von Döhner, Konstanze, Schlenk, Richard F., Habdank, Marianne, Scholl, Claudia, Rücker, Frank G., Corbacioglu, Andrea, Bullinger, Lars, Fröhling, Stefan, Döhner, Hartmut

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Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: an abridged Cochrane network meta‐analysis von Weibel, S., Schaefer, M. S., Raj, D., Rücker, G., Pace, N. L., Schlesinger, T., Meybohm, P., Kienbaum, P., Eberhart, L. H. J., Kranke, P.

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Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia von Krönke, Jan, Bullinger, Lars, Teleanu, Veronica, Tschürtz, Florian, Gaidzik, Verena I., Kühn, Michael W.M., Rücker, Frank G., Holzmann, Karlheinz, Paschka, Peter, Kapp-Schwörer, Silke, Späth, Daniela, Kindler, Thomas, Schittenhelm, Marcus, Krauter, Jürgen, Ganser, Arnold, Göhring, Gudrun, Schlegelberger, Brigitte, Schlenk, Richard F., Döhner, Hartmut, Döhner, Konstanze

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Biomass burning fuel consumption rates: a field measurement database von van Leeuwen, T. T, van der Werf, G. R, Hoffmann, A. A, Detmers, R. G, Rücker, G, French, N. H. F, Archibald, S, Carvalho Jr., J. A, Cook, G. D, de Groot, W. J, Hély, C, Kasischke, E. S, Kloster, S, McCarty, J. L, Pettinari, M. L, Savadogo, P, Alvarado, E. C, Boschetti, L, Manuri, S, Meyer, C. P, Siegert, F, Trollope, L. A, Trollope, W. S. W

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Differences in the placebo response between trials do not necessarily preclude network meta‐analysis von Rücker, G., Schwarzer, G.

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Low‐dose aspirin for secondary cardiovascular prevention – cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation – review and meta‐ana... von BURGER, W., CHEMNITIUS, J.‐M., KNEISSL, G. D., RÜCKER, G.

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Chromothripsis is linked to TP53 alteration, cell cycle impairment, and dismal outcome in acute myeloid leukemia with complex karyotype von Rücker, Frank G, Dolnik, Anna, Blätte, Tamara J, Teleanu, Veronica, Ernst, Aurélie, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Döhner, Hartmut, Döhner, Konstanze, Bullinger, Lars

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Impact of investigator initiated trials and industry sponsored trials on medical practice (IMPACT): rationale and study design von Nury, E., Bischoff, K., Wollmann, K., Nitschke, K., Lohner, S., Schumacher, M., Ruecker, G., Bluemle, A.

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Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia von Lal, Ridhima, Lind, Karin, Heitzer, Ellen, Ulz, Peter, Aubell, Kristina, Kashofer, Karl, Middeke, Jan M., Thiede, Christian, Schulz, Eduard, Rosenberger, Angelika, Hofer, Sybille, Feilhauer, Birgit, Rinner, Beate, Svendova, Vendula, Schimek, Michael G., Rücker, Frank G., Hoefler, Gerald, Döhner, Konstanze, Zebisch, Armin, Wölfler, Albert, Sill, Heinz

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The role of routine SARS-CoV-2 screening of healthcare-workers in acute care hospitals in 2020: a systematic review and meta-analysis von Jabs, J M, Schwabe, A, Wollkopf, A D, Gebel, B, Stadelmaier, J, Erdmann, S, Radicke, F, Grundmann, H, Kramer, A, Monsef, I, Rücker, G, Rupp, J, Scheithauer, S, Schmucker, C, Simon, A, Mutters, Nico T

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Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing von Dolnik, Anna, Engelmann, Julia C., Scharfenberger-Schmeer, Maren, Mauch, Julian, Kelkenberg-Schade, Sabine, Haldemann, Berit, Fries, Tamara, Krönke, Jan, Kühn, Michael W.M., Paschka, Peter, Kayser, Sabine, Wolf, Stephan, Gaidzik, Verena I., Schlenk, Richard F., Rücker, Frank G., Döhner, Hartmut, Lottaz, Claudio, Döhner, Konstanze, Bullinger, Lars

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The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements von Grasedieck, Sarah, Cabantog, Ariene, MacPhee, Liam, Im, Junbum, Ruess, Christoph, Demir, Burcu, Sperb, Nadine, Rücker, Frank G., Döhner, Konstanze, Herold, Tobias, Pollack, Jonathan R., Bullinger, Lars, Rouhi, Arefeh, Kuchenbauer, Florian

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Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia von Uckelmann, Hannah J., Kim, Stephanie M., Wong, Eric M., Hatton, Charles, Giovinazzo, Hugh, Gadrey, Jayant Y., Krivtsov, Andrei V., Ruecker, Frank G., Doehner, Konstanze, McGeehan, Gerard M., Levine, Ross L., Bullinger, Lars, Vassiliou, George S., Armstrong, Scott A.

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A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies von Boettcher, Steffen, Miller, Peter G, Sharma, Rohan, McConkey, Marie, Leventhal, Matthew, Krivtsov, Andrei V, Giacomelli, Andrew O, Wong, Waihay, Kim, Jesi, Chao, Sherry, Kurppa, Kari J, Yang, Xiaoping, Milenkowic, Kirsten, Piccioni, Federica, Root, David E, Rücker, Frank G, Flamand, Yael, Neuberg, Donna, Lindsley, R Coleman, Jänne, Pasi A, Hahn, William C, Jacks, Tyler, Döhner, Hartmut, Armstrong, Scott A, Ebert, Benjamin L

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Disclosure of Candidate Genes in Acute Myeloid Leukemia With Complex Karyotypes Using Microarray-Based Molecular Characterization von RÜCKER, Frank G, BULLINGER, Lars, RADLWIMMER, Bernhard, KESTLER, Hans A, POLLACK, Jonathan R, LICHTER, Peter, DOHNER, Konstanze, DÖHNER, Hartmut, SCHWAENEN, Carsten, LIPKA, Daniel B, WESSENDORF, Swen, FRÖHLING, Stefan, BENTZ, Martin, MILLER, Simone, SCHOLL, Claudia, SCHLENK, Richard F

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Integrative nucleophosmin mutation-associated microRNA and gene expression pattern analysis identifies novel microRNA - target gene interactions in acute myeloid leukemia von Russ, A. C., Sander, S., Luck, S. C., Lang, K. M., Bauer, M., Rucker, F. G., Kestler, H. A., Schlenk, R. F., Dohner, H., Holzmann, K., Dohner, K., Bullinger, L.

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Biopsy-derived oral keratinocytes – A model to potentially test for oral mucosa radiation sensitivity von Thomsen, A.R., Aldrian, C., Luka, B., Hornhardt, S., Huber, K., Gomolka, M., Moertl, S., Hess, J., Zitzelsberger, H., Heider, T., Schlueter, N., Rau, S., Monroy Ordonez, B., Schäfer, H., Rücker, G., Henke, M.

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Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations von Rausch, Tobias, Jones, David T.W., Zapatka, Marc, Stütz, Adrian M., Zichner, Thomas, Weischenfeldt, Joachim, Jäger, Natalie, Remke, Marc, Shih, David, Northcott, Paul A., Pfaff, Elke, Tica, Jelena, Wang, Qi, Massimi, Luca, Witt, Hendrik, Bender, Sebastian, Pleier, Sabrina, Cin, Huriye, Hawkins, Cynthia, Beck, Christian, von Deimling, Andreas, Hans, Volkmar, Brors, Benedikt, Eils, Roland, Scheurlen, Wolfram, Blake, Jonathon, Benes, Vladimir, Kulozik, Andreas E., Witt, Olaf, Martin, Dianna, Zhang, Cindy, Porat, Rinnat, Merino, Diana M., Wasserman, Jonathan, Jabado, Nada, Fontebasso, Adam, Bullinger, Lars, Rücker, Frank G., Döhner, Konstanze, Döhner, Hartmut, Koster, Jan, Molenaar, Jan J., Versteeg, Rogier, Kool, Marcel, Tabori, Uri, Malkin, David, Korshunov, Andrey, Taylor, Michael D., Lichter, Peter, Pfister, Stefan M., Korbel, Jan O.

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