Molecular Mechanisms of Isocitrate Dehydrogenase 1 Mutants in Driving the Oncogenic Neomorphic Reaction von Quichocho, Giovanni Garrido, Xu, Ruth, Luna, Lucas, Matteo, Diego Avellaneda, Scott, Michelle, Fonbon, Jeon Erik, Sohl, Christal D.

Volltext

The Catalytic Features of IDH1 Mutations Can Drive Neomorphic Activity, Phenotype Severity, and Inhibitor Binding von Sohl, Christal D., Matteo, Diego Avellaneda, Wells, Grace, Luna, Lucas, Upadhye, Viraj, Quichocho, Giovanni, Chambers, Jennifer M., Miller, Wade, Scott, David, Schiffer, Jamie M.

Volltext

Water Networks and Correlated Motions in Mutant Isocitrate Dehydrogenase 1 (IDH1) Are Critical for Allosteric Inhibitor Binding and Activity von Chambers, Jennifer M, Miller, Wade, Quichocho, Giovanni, Upadhye, Viraj, Matteo, Diego Avellaneda, Bobkov, Andrey A, Sohl, Christal D, Schiffer, Jamie M

Volltext