Biological activity of neosergeolide and isobrucein B (and two semi-synthetic derivatives) isolated from the Amazonian medicinal plant Picrolemma sprucei (Simaroubaceae) von Silva, Ellen CC, Cavalcanti, Bruno C, Amorim, Rodrigo CN, Lucena, Jorcilene F, Quadros, Dulcimar S, Tadei, Wanderli P, Montenegro, Raquel C, Costa-Lotufo, Letícia V, Pessoa, Cláudia, Moraes, Manoel O, Nunomura, Rita CS, Nunomura, Sergio M, Melo, Marcia RS, de Andrade-Neto, Valter F, Silva, Luiz Francisco R, Vieira, Pedro Paulo R, Pohlit, Adrian M

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