Parallel Signaling through IRE1α and PERK Regulates Pancreatic Neuroendocrine Tumor Growth and Survival von Moore, Paul C, Qi, Jenny Y, Thamsen, Maike, Ghosh, Rajarshi, Peng, Justin, Gliedt, Micah J, Meza-Acevedo, Rosa, Warren, Rachel E, Hiniker, Annie, Kim, Grace E, Maly, Dustin J, Backes, Bradley J, Papa, Feroz R, Oakes, Scott A

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Asymmetric inhibition of Ulk2 causes left-right differences in habenular neuropil formation von Taylor, Robert W, Qi, Jenny Y, Talaga, Anna K, Ma, Taylur P, Pan, Luyuan, Bartholomew, Clinton R, Klionsky, Daniel J, Moens, Cecilia B, Gamse, Joshua T

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The Unfolded Protein Response Regulates Pancratic Neuroendocrine Tumor Growth von Oakes, Scott A., Qi, Jenny Y., Moore, Paul C, Warren, Rachel A., Thamsen, Maike, Ghosh, Rajarshi, Gliedt, Micah J., Maly, Dustin J., Backes, Bradley J, Papa, Feroz R.

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Pancreatic Neuroendocrine Tumors Require Homeostatic Signaling from the Unfolded Protein Response von Oakes, Scott A., Moore, Paul C., Qi, Jenny Y., Warren, Rachel, Thamsen, Maike, Ghosh, Rajarshi, Gliedt, Micah J., Hiniker, Anne, Kim, Grace E., Maly, Dustin J., Backes, Bradley J., Papa, Feroz R.

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Abstract 2862: The balance of divergent IRE1α signaling regulates pancreatic neuroendocrine tumor growth von Qi, Jenny Y., Moore, Paul C., Thamsen, Maike, Ghosh, Rajarshi, Gliedt, Micah J., Maly, Dustin J., Backes, Bradley J., Papa, Feroz R., Oakes, Scott A.

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NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses von Guo, Haitao, König, Renate, Deng, Meng, Riess, Maximilian, Mo, Jinyao, Zhang, Lu, Petrucelli, Alex, Yoh, Sunnie M., Barefoot, Brice, Samo, Melissa, Sempowski, Gregory D., Zhang, Aiping, Colberg-Poley, Anamaris M., Feng, Hui, Lemon, Stanley M., Liu, Yong, Zhang, Yanping, Wen, Haitao, Zhang, Zhigang, Damania, Blossom, Tsao, Li-Chung, Wang, Qi, Su, Lishan, Duncan, Joseph A., Chanda, Sumit K., Ting, Jenny P.-Y.

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Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication von Guo, Haitao, Wang, Qi, Ghneim, Khader, Wang, Li, Rampanelli, Elena, Holley-Guthrie, Elizabeth, Cheng, Liang, Garrido, Carolina, Margolis, David M., Eller, Leigh A., Robb, Merlin L., Sekaly, Rafick-Pierre, Chen, Xian, Su, Lishan, Ting, Jenny P.-Y.

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The pan-cancer lncRNA PLANE regulates an alternative splicing program to promote cancer pathogenesis von Teng, Liu, Feng, Yu Chen, Guo, Su Tang, Wang, Pei Lin, Qi, Teng Fei, Yue, Yi Meng, Wang, Shi Xing, Zhang, Sheng Nan, Tang, Cai Xia, La, Ting, Zhang, Yuan Yuan, Zhao, Xiao Hong, Gao, Jin Nan, Wei, Li Yuan, Zhang, Didi, Wang, Jenny Y., Shi, Yujie, Liu, Xiao Ying, Li, Jin Ming, Cao, Huixia, Liu, Tao, Thorne, Rick F., Jin, Lei, Shao, Feng-Min, Zhang, Xu Dong

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Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction von Cheng, Chun-Ting, Qi, Yue, Wang, Yi-Chang, Chi, Kevin K., Chung, Yiyin, Ouyang, Ching, Chen, Yun-Ru, Oh, Myung Eun, Sheng, Xiangpeng, Tang, Yulong, Liu, Yun-Ru, Lin, H. Helen, Kuo, Ching-Ying, Schones, Dustin, Vidal, Christina M., Chu, Jenny C.-Y., Wang, Hung-Jung, Chen, Yu-Han, Miller, Kyle M., Chu, Peiguo, Yen, Yun, Jiang, Lei, Kung, Hsing-Jien, Ann, David K.

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Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression von Claringbould, Annique, Westra, Harm-Jan, Bonder, Marc Jan, Deelen, Patrick, Kirsten, Holger, Saha, Ashis, Yazar, Seyhan, Brugge, Harm, Oelen, Roy, de Vries, Dylan H., van der Wijst, Monique G. P., Kasela, Silva, Pervjakova, Natalia, Alves, Isabel, Favé, Marie-Julie, Agbessi, Mawussé, Christiansen, Mark W., Jansen, Rick, Seppälä, Ilkka, Tong, Lin, Teumer, Alexander, Schramm, Katharina, Hemani, Gibran, Verlouw, Joost, Yaghootkar, Hanieh, Sönmez Flitman, Reyhan, Brown, Andrew, Kukushkina, Viktorija, Kalnapenkis, Anette, Rüeger, Sina, Porcu, Eleonora, Kettunen, Johannes, Lee, Bernett, Zhang, Futao, Qi, Ting, Arindrarto, Wibowo, Beutner, Frank, Dmitrieva, Julia, Elansary, Mahmoud, Fairfax, Benjamin P., Georges, Michel, Heijmans, Bastiaan T., Hewitt, Alex W., Kähönen, Mika, Kim, Yungil, Knight, Julian C., Kovacs, Peter, Krohn, Knut, Li, Shuang, Loeffler, Markus, Marigorta, Urko M., Mei, Hailang, Momozawa, Yukihide, Müller-Nurasyid, Martina, Nauck, Matthias, Nivard, Michel G., Penninx, Brenda W. J. H., Pritchard, Jonathan K., Raitakari, Olli T., Rotzschke, Olaf, Slagboom, Eline P., Stehouwer, Coen D. A., Stumvoll, Michael, Sullivan, Patrick, ’t Hoen, Peter A. C., Thiery, Joachim, Tönjes, Anke, van Dongen, Jenny, van Iterson, Maarten, Veldink, Jan H., Völker, Uwe, Warmerdam, Robert, Wijmenga, Cisca, Swertz, Morris, Andiappan, Anand, Montgomery, Grant W., Ripatti, Samuli, Perola, Markus, Kutalik, Zoltan, Dermitzakis, Emmanouil, Bergmann, Sven, van Meurs, Joyce, Prokisch, Holger, Ahsan, Habibul, Pierce, Brandon L., Lehtimäki, Terho, Psaty, Bruce M., Gharib, Sina A., Awadalla, Philip, Milani, Lili, Ouwehand, Willem H., Downes, Kate, Stegle, Oliver, Battle, Alexis, Visscher, Peter M., Yang, Jian, Powell, Joseph, Gibson, Greg, Esko, Tõnu, Franke, Lude

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Prevalence and Profiles of Late-Onset Hearing Loss in Preschool Children with Autism Spectrum Disorder Who Passed Newborn Hearing Screening in a South East Asian Population von Ting, Fang Ni, Kiing, Jennifer S. H., Li, Wei Wen, Chan, Yiong Huak, Loo, Jenny H. Y., Kang, Ying Qi

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A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1-insensitive models of triple-negative breast cancer von Cheng, Ning, Watkins-Schulz, Rebekah, Junkins, Robert D, David, Clément N, Johnson, Brandon M, Montgomery, Stephanie A, Peine, Kevin J, Darr, David B, Yuan, Hong, McKinnon, Karen P, Liu, Qi, Miao, Lei, Huang, Leaf, Bachelder, Eric M, Ainslie, Kristy M, Ting, Jenny P-Y

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Antihistamine Drug Ebastine Inhibits Cancer Growth by Targeting Polycomb Group Protein EZH2 von Li, Qiaqia, Liu, Kilia Y, Liu, Qipeng, Wang, Guangyu, Jiang, Weihua, Meng, Qingshu, Yi, Yang, Yang, Yongyong, Wang, Rui, Zhu, Sen, Li, Chao, Wu, Longxiang, Zhao, Dongyu, Yan, Lin, Zhang, Lili, Kim, Jung-Sun, Zu, Xiongbing, Kozielski, Anthony J, Qian, Wei, Chang, Jenny C, Patnaik, Akash, Chen, Kaifu, Cao, Qi

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Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury von Hu, Yi, Yang, Chun, Amorim, Tania, Maqbool, Mohsin, Lin, Jenny, Li, Chen, Fang, Chuanfeng, Xue, Li, Kwart, Ariel, Fang, Hua, Yin, Mei, Janocha, Allison J, Tsuchimoto, Daisuke, Nakabeppu, Yusaku, Jiang, Xiaofeng, Mejia-Garcia, Alex, Anwer, Faiz, Khouri, Jack, Qi, Xin, Zheng, Qing Y, Yu, Jennifer S, Yan, Shan, LaFramboise, Thomas, Anderson, Kenneth C, Herlitz, Leal C, Munshi, Nikhil C, Lin, Jianhong, Zhao, Jianjun

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Negatively charged phospholipids accelerate the membrane fusion activity of the plant-specific insert domain of an aspartic protease von Zhao, Xiaoli, Ma, Xiaomin, Dupius, John H., Qi, Ruxi, Tian, Jenny (Jingxin), Chen, Jiaxin, Ou, Xiuyuan, Qian, Zhaohui, Liang, Dehai, Wang, Peiyi, Yada, Rickey Y., Wang, Shenlin

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Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease von Zeitler, Bryan, Froelich, Steven, Marlen, Kimberly, Shivak, David A, Yu, Qi, Li, Davis, Pearl, Jocelynn R, Miller, Jeffrey C, Zhang, Lei, Paschon, David E, Hinkley, Sarah J, Ankoudinova, Irina, Lam, Stephen, Guschin, Dmitry, Kopan, Lexi, Cherone, Jennifer M, Nguyen, Hoang-Oanh B, Qiao, Guijuan, Ataei, Yasaman, Mendel, Matthew C, Amora, Rainier, Surosky, Richard, Laganiere, Josee, Vu, B Joseph, Narayanan, Anand, Sedaghat, Yalda, Tillack, Karsten, Thiede, Christina, Gärtner, Annette, Kwak, Seung, Bard, Jonathan, Mrzljak, Ladislav, Park, Larry, Heikkinen, Taneli, Lehtimäki, Kimmo K, Svedberg, Marie M, Häggkvist, Jenny, Tari, Lenke, Tóth, Miklós, Varrone, Andrea, Halldin, Christer, Kudwa, Andrea E, Ramboz, Sylvie, Day, Michelle, Kondapalli, Jyothisri, Surmeier, D James, Urnov, Fyodor D, Gregory, Philip D, Rebar, Edward J, Muñoz-Sanjuán, Ignacio, Zhang, H Steve

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Effective pulmonary delivery of an aerosolized plasmid DNA vaccine via surface acoustic wave nebulization von Rajapaksa, Anushi E, Ho, Jenny J, Qi, Aisha, Bischof, Rob, Nguyen, Tri-Hung, Tate, Michelle, Piedrafita, David, McIntosh, Michelle P, Yeo, Leslie Y, Meeusen, Els, Coppel, Ross L, Friend, James R

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Inhalable Dry Powder Formulations of siRNA and pH-Responsive Peptides with Antiviral Activity Against H1N1 Influenza Virus von Liang, Wanling, Chow, Michael Y. T, Lau, Pui Ngan, Zhou, Qi Tony, Kwok, Philip C. L, Leung, George P. H, Mason, A. James, Chan, Hak-Kim, Poon, Leo L. M, Lam, Jenny K. W

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Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks von Drake, Thomas A, Wang, Kai, MacNeil, Douglas J, Lusis, Aldons J, Ghazalpour, Anatole, Coon, Michael, Xie, Tao, Zhu, Jun, Wang, Susanna S, Schadt, Eric E, Yang, Xia, Kleinhanz, Robert R, Castellani, Lawrence W, Qian, Su, Falkard, Brie, Lum, Pek Y, Reitman, Marc L, Majid, Sana, Mehrabian, Margarete, Zhang, Bin, Deignan, Joshua L, Zhong, Judy, Farber, Charles R, Torosyan, Gevork, Mumick, Sheena, Estrada-Smith, Daria, Zhang, Chunsheng, Dipple, Katrina M, van Nas, Atila, Lamb, John R, Qi, Hongxiu, Karlsson, Jenny

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A phase 1, first-in-human, open-label, dose escalation and dose expansion study of TST005 in patients with locally advanced or metastatic solid tumors von Tolcher, Anthony W., Wu, Xiaohua, Zhang, Jian, Barve, Minal A., Gabrail, Nashat Y., Sommerhalder, David, Rodriguez Rivera, Ildefonso I, Wilks, Sharon, Wu, Yong, Liu, Rujiao, Gao, Shuiping, Valiyil, Akhilkrishna, Sayi, Ntombizodwa, Germa, Caroline, Qi, Charlie, Chen, LEI, Yu, Steven, Yao, Jenny, Zhu, Xuelian

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