Allopregnanolone Mediates Affective Switching Through Modulation of Oscillatory States in the Basolateral Amygdala von Antonoudiou, Pantelis, Colmers, Phillip L.W., Walton, Najah L., Weiss, Grant L., Smith, Anne C., Nguyen, David P., Lewis, Mike, Quirk, Michael C., Barros, Lea, Melon, Laverne C., Maguire, Jamie L.

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Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABAA receptor positive allosteric modulator von Althaus, Alison L., Ackley, Michael A., Belfort, Gabriel M., Gee, Steven M., Dai, Jing, Nguyen, David P., Kazdoba, Tatiana M., Modgil, Amit, Davies, Paul A., Moss, Stephen J., Salituro, Francesco G., Hoffmann, Ethan, Hammond, Rebecca S., Robichaud, Albert J., Quirk, Michael C., Doherty, James J.

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Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABA A receptor positive allosteric modulator von Althaus, Alison L, Ackley, Michael A, Belfort, Gabriel M, Gee, Steven M, Dai, Jing, Nguyen, David P, Kazdoba, Tatiana M, Modgil, Amit, Davies, Paul A, Moss, Stephen J, Salituro, Francesco G, Hoffmann, Ethan, Hammond, Rebecca S, Robichaud, Albert J, Quirk, Michael C, Doherty, James J

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Stimulus-specific adaptation in auditory cortex is an NMDA-independent process distinct from the sensory novelty encoded by the mismatch negativity von Farley, Brandon J, Quirk, Michael C, Doherty, James J, Christian, Edward P

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Adjunctive Lanicemine (AZD6765) in Patients with Major Depressive Disorder and History of Inadequate Response to Antidepressants: A Randomized, Placebo-Controlled Study von Sanacora, Gerard, Johnson, Michael R, Khan, Arif, Atkinson, Sarah D, Riesenberg, Robert R, Schronen, Juan P, Burke, Michael A, Zajecka, John M, Barra, Luis, Su, Hong-Lin, Posener, Joel A, Bui, Khanh H, Quirk, Michael C, Piser, Timothy M, Mathew, Sanjay J, Pathak, Sanjeev

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Pharmacological characterization of SAGE‐718, a novel positive allosteric modulator of N‐methyl‐d‐aspartate receptors von Beckley, Jacob T., Aman, Teresa K., Ackley, Michael A., Kazdoba, Tatiana M., Lewis, Michael C., Smith, Anne C., Farley, Brandon J., Dai, Jing, Deats, Wayne, Hoffmann, Ethan, Robichaud, Albert J., Doherty, James J., Quirk, Michael C.

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SAGE-718: A First-in-Class N‑Methyl‑d‑Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment von Hill, Matthew D., Blanco, Maria-Jesus, Salituro, Francesco G., Bai, Zhu, Beckley, Jacob T., Ackley, Michael A., Dai, Jing, Doherty, James J., Harrison, Boyd L., Hoffmann, Ethan C., Kazdoba, Tatiana M., Lanzetta, David, Lewis, Michael, Quirk, Michael C., Robichaud, Albert J.

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Representation of Spatial Goals in Rat Orbitofrontal Cortex von Feierstein, Claudia E., Quirk, Michael C., Uchida, Naoshige, Sosulski, Dara L., Mainen, Zachary F.

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Hippocampal CA3 NMDA Receptors Are Crucial for Memory Acquisition of One-Time Experience von Nakazawa, Kazu, Sun, Linus D, Quirk, Michael C, Rondi-Reig, Laure, Wilson, Matthew A, Tonegawa, Susumu

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Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological con... von Tang, Weiting, Beckley, Jacob T., Zhang, Jin, Song, Rui, Xu, Yuchen, Kim, Sukhan, Quirk, Michael C., Robichaud, Albert J., Diaz, Eva Sarai, Myers, Scott J., Doherty, James J., Ackley, Michael A., Traynelis, Stephen F., Yuan, Hongjie

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Requirement for Hippocampal CA3 NMDA Receptors in Associative Memory Recall von Nakazawa, Kazu, Quirk, Michael C., Chitwood, Raymond A., Watanabe, Masahiko, Yeckel, Mark F., Sun, Linus D., Kato, Akira, Carr, Candice A., Johnston, Daniel, Wilson, Matthew A., Tonegawa, Susumu

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Neuroactive Steroid N‑Methyl‑d‑aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological Activity von La, Daniel S, Salituro, Francesco G, Martinez Botella, Gabriel, Griffin, Andrew M, Bai, Zhu, Ackley, Michael A, Dai, Jing, Doherty, James J, Harrison, Boyd L, Hoffmann, Ethan C, Kazdoba, Tatiana M, Lewis, Michael C, Quirk, Michael C, Robichaud, Albert J

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A Selective Allosteric Potentiator of the M1 Muscarinic Acetylcholine Receptor Increases Activity of Medial Prefrontal Cortical Neurons and Restores Impairments in Reversal Learnin... von Shirey, Jana K, Brady, Ashley E, Jones, Paulianda J, Davis, Albert A, Bridges, Thomas M, Kennedy, J. Phillip, Jadhav, Satyawan B, Menon, Usha N, Xiang, Zixiu, Watson, Mona L, Christian, Edward P, Doherty, James J, Quirk, Michael C, Snyder, Dean H, Lah, James J, Levey, Allan I, Nicolle, Michelle M, Lindsley, Craig W, Conn, P. Jeffrey

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EEG-β/γ spectral power elevation in rat: a translatable biomarker elicited by GABA(Aα2/3)-positive allosteric modulators at nonsedating anxiolytic doses von Christian, Edward P, Snyder, Dean H, Song, Wei, Gurley, David A, Smolka, Joanne, Maier, Donna L, Ding, Min, Gharahdaghi, Farzin, Liu, Xiaodong F, Chopra, Maninder, Ribadeneira, Maria, Chapdelaine, Marc J, Dudley, Adam, Arriza, Jeffrey L, Maciag, Carla, Quirk, Michael C, Doherty, James J

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A Statistical Paradigm for Neural Spike Train Decoding Applied to Position Prediction from Ensemble Firing Patterns of Rat Hippocampal Place Cells von Brown, Emery N, Frank, Loren M, Tang, Dengda, Quirk, Michael C, Wilson, Matthew A

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Selective alpha 7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes von Sydserff, Simon, Sutton, E J, Song, Dekun, Quirk, Michael C, Maciag, Carla, Li, Chaoying, Jonak, Gerald, Gurley, David, Gordon, John C, Christian, Edward P, Doherty, James J, Hudzik, Tom, Johnson, Edwin, Mrzljak, Ladislav, Piser, Tim, Smagin, Gennady N, Wang, Yi, Widzowski, Dan, Smith, Jeffrey S

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Selective α7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes von Sydserff, Simon, Sutton, E.J., Song, Dekun, Quirk, Michael C., Maciag, Carla, Li, Chaoying, Jonak, Gerald, Gurley, David, Gordon, John C., Christian, Edward P., Doherty, James J., Hudzik, Tom, Johnson, Edwin, Mrzljak, Ladislav, Piser, Tim, Smagin, Gennady N., Wang, Yi, Widzowski, Dan, Smith, Jeffrey S.

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Construction and analysis of non-Poisson stimulus-response models of neural spiking activity von Barbieri, Riccardo, Quirk, Michael C, Frank, Loren M, Wilson, Matthew A, Brown, Emery N

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Dynamic Analyses of Information Encoding in Neural Ensembles von Barbieri, Riccardo, Frank, Loren M., Nguyen, David P., Quirk, Michael C., Solo, Victor, Wilson, Matthew A., Brown, Emery N.

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A defined network of fast-spiking interneurons in orbitofrontal cortex: responses to behavioral contingencies and ketamine administration von Quirk, Michael C, Sosulski, Dara L, Feierstein, Claudia E, Uchida, Naoshige, Mainen, Zachary F

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