Immunotherapeutic Synergy Between Anti-CD137 mAb and Intratumoral Administration of a Cytopathic Semliki Forest Virus Encoding IL-12 von Quetglas, José I, Dubrot, Juan, Bezunartea, Jaione, Sanmamed, Miguel F, Hervas-Stubbs, Sandra, Smerdou, Cristian, Melero, Ignacio

Volltext

Small Rho GTPases and Cholesterol Biosynthetic Pathway Intermediates in African Swine Fever Virus Infection von Quetglas, Jose I, Hernáez, Bruno, Galindo, Inmaculada, Muñoz-Moreno, Raquel, Cuesta-Geijo, Miguel A, Alonso, Covadonga

Volltext

Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb von Weigelin, Bettina, Elixabet Bolaños, Alvaro Teijeira, Ivan Martinez-Forero, Sara Labiano, Arantza Azpilikueta, Aizea Morales-Kastresana, Josñé I. Quetglas, Esther Wagena, Alfonso Rodrñéíguez Sñéíánchez-Paulete, Lieping Chen, Peter Friedl, Ignacio Melero

Volltext

Routing cancer immunology and immunotherapy from the lab to the clinic 4-5 th March 2014, Center for Applied Medical Research and University Clinic, Pamplona, Spain von Aznar, M Ángela, Melero, Ignacio, Quetglas, José I

Volltext

Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells von Etxeberria, Iñaki, Bolaños, Elixabet, Quetglas, Jose I., Gros, Alena, Villanueva, Alberto, Palomero, Jara, Sánchez-Paulete, Alfonso R., Piulats, Jose María, Matias-Guiu, Xavier, Olivera, Irene, Ochoa, Maria C., Labiano, Sara, Garasa, Saray, Rodriguez, Inmaculada, Vidal, August, Mancheño, Uxua, Hervás-Stubbs, Sandra, Azpilikueta, Arantza, Otano, Itziar, Aznar, M. Angela, Sanmamed, Miguel F., Inogés, Susana, Berraondo, Pedro, Teijeira, Álvaro, Melero, Ignacio

Volltext

Cancer Immunotherapy with Immunomodulatory Anti-CD137 and Anti-PD-1 Monoclonal Antibodies Requires BATF3-Dependent Dendritic Cells von Sánchez-Paulete, Alfonso R, Cueto, Francisco J, Martínez-López, María, Labiano, Sara, Morales-Kastresana, Aizea, Rodríguez-Ruiz, María E, Jure-Kunkel, Maria, Azpilikueta, Arantza, Aznar, M Angela, Quetglas, José I, Sancho, David, Melero, Ignacio

Volltext

Antibodies against Marinobacter algicola and Salmonella typhimurium flagellins do not cross-neutralize TLR5 activation von Terron-Exposito, Raul, Dudognon, Benoit, Galindo, Inmaculada, Quetglas, Jose I, Coll, Julio M, Escribano, Jose M, Gomez-Casado, Eduardo

Volltext

Semliki Forest Virus Expressing Interleukin-12 Induces Antiviral and Antitumoral Responses in Woodchucks with Chronic Viral Hepatitis and Hepatocellular Carcinoma von RODRIGUEZ-MADOZ, Juan R, LIU, Katherine H, PRIETO, Jesus, GONZALEZ-ASEGUINOLAZA, Gloria, SMERDOU, Cristian, MENNE, Stephan, QUETGLAS, Jose I, RUIZ-GUILLEN, Marta, OTANO, Itziar, CRETTAZ, Julien, BUTLER, Scott D, BELLEZZA, Christine A, DYKES, Nathan L, TENNANT, Bud C

Volltext

Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus-Derived Vectors Fosters Dendritic Cell-Mediated T-cell Cross-Priming von Sánchez-Paulete, Alfonso R, Teijeira, Álvaro, Quetglas, José I, Rodríguez-Ruiz, María E, Sánchez-Arráez, Álvaro, Labiano, Sara, Etxeberria, Iñaki, Azpilikueta, Arantza, Bolaños, Elixabet, Ballesteros-Briones, María Cristina, Casares, Noelia, Quezada, Sergio A, Berraondo, Pedro, Sancho, David, Smerdou, Cristian, Melero, Ignacio

Volltext

Alphavirus vectors for cancer therapy von Quetglas, Jose I., Ruiz-Guillen, Marta, Aranda, Alejandro, Casales, Erkuden, Bezunartea, Jaione, Smerdou, Cristian

Volltext

Virotherapy with a Semliki Forest Virus-Based Vector Encoding IL12 Synergizes with PD-1/PD-L1 Blockade von Quetglas, José I, Labiano, Sara, Aznar, M Ángela, Bolaños, Elixabet, Azpilikueta, Arantza, Rodriguez, Inmaculada, Casales, Erkuden, Sánchez-Paulete, Alfonso R, Segura, Víctor, Smerdou, Cristian, Melero, Ignacio

Volltext

Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12 von Melero, Ignacio, Quetglas, Jose I, Reboredo, Mercedes, Dubrot, Juan, Rodriguez-Madoz, Juan R, Mancheño, Uxua, Casales, Erkuden, Riezu-Boj, Jose I, Ruiz-Guillen, Marta, Ochoa, Maria C, Sanmamed, Miguel F, Thieblemont, Nathalie, Smerdou, Cristian, Hervas-Stubbs, Sandra

Volltext

Better Performance of CARs Deprived of the PD-1 Brake von MORALES-KASTRESANA, Aizea, LABIANO, Sara, QUETGLAS, José I, MELERO, Ignacio

Volltext

Capsid-deficient alphaviruses generate propagative infectious microvesicles at the plasma membrane von Ruiz-Guillen, Marta, Gabev, Evgeni, Quetglas, Jose I., Casales, Erkuden, Ballesteros-Briones, María Cristina, Poutou, Joanna, Aranda, Alejandro, Martisova, Eva, Bezunartea, Jaione, Ondiviela, Marina, Prieto, Jesus, Hernandez-Alcoceba, Ruben, Abrescia, Nicola G. A., Smerdou, Cristian

Volltext

Hypoxia-induced soluble CD137 in malignant cells blocks CD137L-costimulation as an immune escape mechanism von Labiano, Sara, Palazón, Asis, Bolaños, Elixabet, Azpilikueta, Arantza, Sánchez-Paulete, Alfonso R., Morales-Kastresana, Aizea, Quetglas, Jose I., Perez-Gracia, José L., Gúrpide, Alfonso, Rodriguez-Ruiz, Maria, Aznar, M. Angela, Jure-Kunkel, Maria, Berraondo, Pedro, Melero, Ignacio

Volltext

Protein pE120R of African swine fever virus is post-translationally acetylated as revealed by post-source decay MALDI mass spectrometry von Alfonso, Patricia, Quetglas, José I, Escribano, José M, Alonso, Covadonga

Volltext

A Simple and Efficient In Vivo Non-viral RNA Transfection Method for Labeling the Whole Axonal Tree of Individual Adult Long-Range Projection Neurons von Porrero, César, Rodríguez-Moreno, Javier, Quetglas, José I, Smerdou, Cristian, Furuta, Takahiro, Clascá, Francisco

Volltext

Enhanced therapeutic effect using sequential administration of antigenically distinct oncolytic viruses expressing oncostatin M in a Syrian hamster orthotopic pancreatic cancer mod... von Nistal-Villan, Estanislao, Bunuales, Maria, Poutou, Joanna, Gonzalez-Aparicio, Manuela, Bravo-Perez, Carlos, Quetglas, Jose I, Carte, Beatriz, Gonzalez-Aseguinolaza, Gloria, Prieto, Jesus, Larrea, Esther, Hernandez-Alcoceba, Ruben

Volltext

Eradication of liver-implanted tumors by Semliki Forest virus expressing IL-12 requires efficient long-term immune responses von Quetglas, Jose I, Rodriguez-Madoz, Juan R, Bezunartea, Jaione, Ruiz-Guillen, Marta, Casales, Erkuden, Medina-Echeverz, Jose, Prieto, Jesus, Berraondo, Pedro, Hervas-Stubbs, Sandra, Smerdou, Cristian

Volltext

A novel system for the production of high levels of functional human therapeutic proteins in stable cells with a Semliki Forest virus noncytopathic vector von Casales, Erkuden, Aranda, Alejandro, Quetglas, Jose I., Ruiz-Guillen, Marta, Rodriguez-Madoz, Juan R., Prieto, Jesus, Smerdou, Cristian

Volltext