PCSK9 VACCINE PCSK9 von ULLAH, JAKIR, HUSSAIN JH, QIU, XIAYANG X, PIERCE, BRIAN, GREGORY BG, FRASER, JAMES, DOWNEY JD, MERSON, JAMES, RICHARD JR, EISENBRAUN, MICHAEL, DALE MD, CHAMPION, BRIAN, ROBERT BR, CONTILLO, JR., LEONARD, GABRIEL LG, HAWKINS, JULIE, JIA, LI JJL, WYATT, DAVID, MICHAEL DM

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PCSK9 VACCINE PCSK9 von ULLAH, JAKIR, HUSSAIN JH, QIU, XIAYANG X, PIERCE, BRIAN, GREGORY BG, FRASER, JAMES, DOWNEY JD, MERSON, JAMES, RICHARD JR, EISENBRAUN, MICHAEL, DALE MD, CHAMPION, BRIAN, ROBERT BR, CONTILLO, JR., LEONARD, GABRIEL LG, HAWKINS, JULIE, JIA, LI JJL, WYATT, DAVID, MICHAEL DM

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PCSK9 VACCINE PCSK9 von ULLAH, JAKIR, HUSSAIN JH, QIU, XIAYANG X, PIERCE, BRIAN, GREGORY BG, FRASER, JAMES, DOWNEY JD, MERSON, JAMES, RICHARD JR, EISENBRAUN, MICHAEL, DALE MD, CHAMPION, BRIAN, ROBERT BR, CONTILLO, JR., LEONARD, GABRIEL LG, HAWKINS, JULIE, JIA, LI JJL, WYATT, DAVID, MICHAEL DM

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A Model for the Mechanism of Human Topoisomerase I von Stewart, Lance, Redinbo, Matthew R., Qui, Xiayang, Wim G. J. Hol, Champoux, James J.

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Biophysical and Mechanistic Insights into Novel Allosteric Inhibitor of Spleen Tyrosine Kinase von Hall, Justin, Aulabaugh, Ann, Rajamohan, Francis, Liu, Shenping, Kaila, Neelu, Wan, Zhao-Kui, Ryan, Mark, Magyar, Rachelle, Qiu, Xiayang

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Refined structures of β-ketoacyl-acyl carrier protein synthase III von Qiu, Xiayang, Janson, Cheryl A, Smith, Ward W, Head, Martha, Lonsdale, John, Konstantinidis, Alex K

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Crystal structure and substrate specificity of the β‐ketoacyl‐acyl carrier protein synthase III (FabH) from Staphylococcus aureus von Qiu, Xiayang, Choudhry, Anthony E., Janson, Cheryl A., Grooms, Michael, Daines, Robert A., Lonsdale, John T., Khandekar, Sanjay S.

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First X-ray Cocrystal Structure of a Bacterial FabH Condensing Enzyme and a Small Molecule Inhibitor Achieved Using Rational Design and Homology Modeling von Daines, Robert A, Pendrak, Israil, Sham, Kelvin, Van Aller, Glenn S, Konstantinidis, Alex K, Lonsdale, John T, Janson, Cheryl A, Qiu, Xiayang, Brandt, Martin, Khandekar, Sanjay S, Silverman, Carol, Head, Martha S

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Crystal structure of Staphylococcus aureus tyrosyl‐tRNA synthetase in complex with a class of potent and specific inhibitors von Qiu, Xiayang, Janson, Cheryl A., Smith, Ward W., Green, Susan M., McDevitt, Patrick, Johanson, Kyung, Carter, Paul, Hibbs, Martin, Lewis, Ceri, Chalker, Alison, Fosberry, Andrew, Lalonde, Judith, Berge, John, Brown, Pamela, Houge‐Frydrych, Catherine S.V., Jarvest, Richard L.

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Crystal structure of beta-ketoacyl-acyl carrier protein synthase III. A key condensing enzyme in bacterial fatty acid biosynthesis von Qiu, X, Janson, C A, Konstantinidis, A K, Nwagwu, S, Silverman, C, Smith, W W, Khandekar, S, Lonsdale, J, Abdel-Meguid, S S

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Indole Naphthyridinones as Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK von Seefeld, Mark A, Miller, William H, Newlander, Kenneth A, Burgess, Walter J, DeWolf, Walter E, Elkins, Patricia A, Head, Martha S, Jakas, Dalia R, Janson, Cheryl A, Keller, Paul M, Manley, Peter J, Moore, Terrance D, Payne, David J, Pearson, Stewart, Polizzi, Brian J, Qiu, Xiayang, Rittenhouse, Stephen F, Uzinskas, Irene N, Wallis, Nicola G, Huffman, William F

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Cholesteryl Ester Transfer Protein Variants Have Differential Stability but Uniform Inhibition by Torcetrapib von Lloyd, David B., Lira, Maruja E., Wood, Linda S., Durham, L. Kathryn, Freeman, Thomas B., Preston, Gregory M., Qiu, Xiayang, Sugarman, Eliot, Bonnette, Peter, Lanzetti, Anthony, Milos, Patrice M., Thompson, John F.

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Molecular basis for triclosan activity involves a flipping loop in the active site von QIU, XIAYANG, JANSON, CHERYL A., COURT, ROBERT I., SMYTH, MARTIN G., PAYNE, DAVID J., ABDEL-MEGUID, SHERIN S.

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1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI) von Heerding, Dirk A, Chan, George, DeWolf, Walter E, Fosberry, Andrew P, Janson, Cheryl A, Jaworski, Deborah D, McManus, Edward, Miller, William H, Moore, Terrance D, Payne, David J, Qiu, Xiayang, Rittenhouse, Stephen F, Slater-Radosti, Courtney, Smith, Ward, Takata, Dennis T, Vaidya, Kalindi S, Yuan, Catherine C.K, Huffman, William F

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Discovery of Aminopyridine-Based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI) von Miller, William H, Seefeld, Mark A, Newlander, Kenneth A, Uzinskas, Irene N, Burgess, Walter J, Heerding, Dirk A, Yuan, Catherine C. K, Head, Martha S, Payne, David J, Rittenhouse, Stephen F, Moore, Terrance D, Pearson, Stewart C, Berry, Valerie, DeWolf, Walter E, Keller, Paul M, Polizzi, Brian J, Qiu, Xiayang, Janson, Cheryl A, Huffman, William F

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Structure of apo acyl carrier protein and a proposal to engineer protein crystallization through metal ions von Qiu, Xiayang, Janson, Cheryl A.

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Unique fold and active site in cytomegalovirus protease von Qiu, Xiayang, Culp, Jeffrey S., DiLella, Anthony G., Hellmig, Brian, Hoog, Susan S., Janson, Cheryl A., Smith, Ward W., Abdel-Meguid, Sherin S.

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Molecular Basis for the Inhibition of Human α-Thrombin by the Macrocyclic Peptide Cyclotheonamide A von Maryanoff, Bruce E., Qiu, Xiayang, Padmanabhan, K. P., Tulinsky, Alexander, Almond, Harold R., Andrade-Gordon, Patricia, Greco, Michael N., Kauffman, Jack A., Nicolaou, K. C., Liu, Aijn, Brungs, Peter H., Fusetani, Nobuhiro

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Crystal Structure of Varicella-Zoster Virus Protease von Qiu, Xiayang, Janson, Cheryl A., Culp, Jeffrey S., Richardson, Susan B., Debouck, Christine, Smith, Ward W., Abdel-Meguid, Sherin S.

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High-Resolution Structure of the Diphtheria Toxin Repressor Complexed with Cobalt and Manganese Reveals an SH3-like Third Domain and Suggests a Possible Role of Phosphate as Co-cor... von Qiu, Xiayang, Pohl, Ehmke, Holmes, Randall K, Hol, Wim G. J

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