Human DNA2 Is a Mitochondrial Nuclease/Helicase for Efficient Processing of DNA Replication and Repair Intermediates von Zheng, Li, Zhou, Mian, Guo, Zhigang, Lu, Huiming, Qian, Limin, Dai, Huifang, Qiu, Junzhuan, Yakubovskaya, Elena, Bogenhagen, Daniel F., Demple, Bruce, Shen, Binghui

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Fen1 mutations result in autoimmunity, chronic inflammation and cancers von Li, Mei, Kernstine, Kemp, Tsark, Walter, Zhou, Mian, Singh, Purnima, Dai, Huifang, Huang, Qin, Qiu, Junzhuan, Zhang, Xuemei, Lin, Dongxin, Shen, Binghui, Zheng, Li

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Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair von Chapados, Brian R, Hosfield, David J, Han, Seungil, Qiu, Junzhuan, Yelent, Biana, Shen, Binghui, Tainer, John A

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Concerted Action of Exonuclease and Gap-dependent Endonuclease Activities of FEN-1 Contributes to the Resolution of Triplet Repeat Sequences (CTG)n- and (GAA)n-derived Secondary St... von Singh, Purnima, Zheng, Li, Chavez, Valerie, Qiu, Junzhuan, Shen, Binghui

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Multiple but dissectible functions of FEN-1 nucleases in nucleic acid processing, genome stability and diseases von Shen, Binghui, Singh, Purnima, Liu, Ren, Qiu, Junzhuan, Zheng, Li, Finger, L. David, Alas, Steve

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Disruption of the FEN-1/PCNA Interaction Results in DNA Replication Defects, Pulmonary Hypoplasia, Pancytopenia, and Newborn Lethality in Mice von Zheng, Li, Dai, Huifang, Qiu, Junzhuan, Huang, Qin, Shen, Binghui

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Mature B Cells Are Critical to T-cell-mediated Tumor Immunity Induced by an Agonist Anti-GITR Monoclonal Antibody von PENGFEI ZHOU, JUNZHUAN QIU, L'ITALIEN, Lawrence, DANLING GU, HODGES, Douglas, CHAO, Cheng-Chi, SCHEBYE, Xiao Min

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Saccharomyces cerevisiae RNase H(35) Functions in RNA Primer Removal during Lagging-Strand DNA Synthesis, Most Efficiently in Cooperation with Rad27 Nuclease von Qiu, Junzhuan, Qian, Ying, Frank, Peter, Wintersberger, Ulrike, Shen, Binghui

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Characterization of the 3‘ → 5‘ Exonuclease Activity Found in Human Nucleoside Diphosphate Kinase 1 (NDK1) and Several of Its Homologues von Yoon, Jung-Hoon, Singh, Purnima, Lee, Dong-Hyun, Qiu, Junzhuan, Cai, Sheng, O'Connor, Timothy R, Chen, Yuan, Shen, Binghui, Pfeifer, Gerd P

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Cell Cycle-dependent and DNA Damage-inducible Nuclear Localization of FEN-1 Nuclease Is Consistent with Its Dual Functions in DNA Replication and Repair von Qiu, Junzhuan, Li, Xinwei, Frank, Geoffrey, Shen, Binghui

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Stimulation of Eukaryotic Flap Endonuclease-1 Activities by Proliferating Cell Nuclear Antigen (PCNA) Is Independent of Its in Vitro Interaction via a Consensus PCNA Binding Region von Frank, Geoffrey, Qiu, Junzhuan, Zheng, Li, Shen, Binghui

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The retinitis pigmentosa-mutated RP2 protein exhibits exonuclease activity and translocates to the nucleus in response to DNA damage von Yoon, Jung-Hoon, Qiu, Junzhuan, Cai, Sheng, Chen, Yuan, Cheetham, Michael E., Shen, Binghui, Pfeifer, Gerd P.

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Human Exonuclease 1 Functionally Complements Its Yeast Homologues in DNA Recombination, RNA Primer Removal, and Mutation Avoidance von Qiu, J, Qian, Y, Chen, V, Guan, M X, Shen, B

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Search for Apoptotic Nucleases in Yeast von Qiu, Junzhuan, Yoon, Jung-Hoon, Shen, Binghui

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Interaction Interface of Human Flap Endonuclease-1 with Its DNA Substrates von Qiu, Junzhuan, Liu, Ren, Chapados, Brian R, Sherman, Mark, Tainer, John A, Shen, Binghui

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Activity of CBT-501, a novel humanized anti-PD-1 antibody, in a humanized genetically engineered mouse model of colon carcinoma von Zhou, Qing, Nian, Weihong, Sun, Ziyong, Qiu, Junzhuan, Wang, Zhun, Choy, Gavin, Redkar, Sanjeev

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Novel Function of Rad27 (FEN-1) in Restricting Short-Sequence Recombination von Negritto, M. Cristina, Qiu, Junzhuan, Ratay, Dawn O., Shen, Binghui, Bailis, Adam M.

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Concerted Action of Exonuclease and Gap-dependent Endonuclease Activities of FEN-1 Contributes to the Resolution of Triplet Repeat Sequences (CTG) - and (GAA) -derived Secondary St... von Singh, Purnima, Zheng, Li, Chavez, Valerie, Qiu, Junzhuan, Shen, Binghui

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Archaeoglobus fulgidus RNase HII in DNA Replication: Enzymological Functions and Activity Regulation via Metal Cofactors von Chai, Qing, Qiu, Junzhuan, Chapados, Brian R., Shen, Binghui

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Abstract A200: CBT-502 (TQB2450), a novel anti-PD-L1 antibody, demonstrates favorable activity in MC-38/H-11 murine colon and A375 human melanoma animal models von Wei, Zhao, Yang, Ling, Li, Yingchun, Lu, Jiansheng, Zhang, Xiquan, Tian, Xin, Zha, Jiping, Sun, Ziyong, Qiu, Junzhuan, Wang, Zhun, Reddy, Mamatha, Choy, Gavin S., Redkar, Sanjeev

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