A new wave of innovations within the DNA damage response von Li, Qi, Qian, Wenyuan, Zhang, Yang, Hu, Lihong, Chen, Shuhui, Xia, Yuanfeng

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A “Click and Activate” Approach in One-Pot Synthesis of a Triazolyl-Pyridazinone Library von Qian, Wenyuan, Winternheimer, David, Allen, Jennifer

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One-pot synthesis of [1,2,3]triazole-fused pyrazinopyridazindione tricycles by a ‘click and activate’ approach von Qian, Wenyuan, Winternheimer, David, Amegadzie, Albert, Allen, Jennifer

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Convergent, Regioselective Synthesis of Tetrakisfulleroids from C60 von Qian, Wenyuan, Rubin, Yves

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Total Synthesis and Structural Elucidation of Azaspiracid-1. Construction of Key Building Blocks for Originally Proposed Structure von Nicolaou, K. C, Pihko, Petri M, Bernal, Federico, Frederick, Michael O, Qian, Wenyuan, Uesaka, Noriaki, Diedrichs, Nicole, Hinrichs, Jürgen, Koftis, Theocharis V, Loizidou, Eriketi, Petrovic, Goran, Rodriquez, Manuela, Sarlah, David, Zou, Ning

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Discovery of dehydro-oxopiperazine acetamides as novel bradykinin B1 receptor antagonists with enhanced in vitro potency von Qian, Wenyuan, Chen, Jian Jeffrey, Human, Jason, Aya, Toshihiro, Zhu, Jiawang, Biswas, Kaustav, Peterkin, Tanya, Hungate, Randall W., Arik, Leyla, Johnson, Eileen, Kumar, Gondi, Joseph, Smriti, Jona, Janan, Guo, Hong-Xun, Wu, Zufan

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Synthesis of Stable Derivatives of C62:  The First Nonclassical Fullerene Incorporating a Four-Membered Ring von Qian, Wenyuan, Chuang, Shih-Ching, Amador, Roberto B, Jarrosson, Thibaut, Sander, Michael, Pieniazek, Susan, Khan, Saeed I, Rubin, Yves

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Copper-Catalyzed Domino Cycloaddition/CN Coupling/Cyclization/(CH Arylation): An Efficient Three-Component Synthesis of Nitrogen Polyheterocycles von Qian, Wenyuan, Wang, Hao, Allen, Jennifer

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Identification of TUL01101: A Novel Potent and Selective JAK1 Inhibitor for the Treatment of Rheumatoid Arthritis von Zhou, Shuhao, Mao, Weiwei, Su, Yuan, Zheng, Xuejian, Qian, Wenyuan, Shen, Meiyue, Shan, Ningli, Li, Yaoshuang, Wang, Degang, Wu, Shouting, Sun, Tiemin, Mu, Liwei

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3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammation von Chen, Jian Jeffrey, Nguyen, Thomas, D’Amico, Derin C., Qian, Wenyuan, Human, Jason, Aya, Toshihiro, Biswas, Kaustav, Fotsch, Christopher, Han, Nianhe, Liu, Qingyian, Nishimura, Nobuko, Peterkin, Tanya A.N., Yang, Kevin, Zhu, Jiawang, Riahi, Babak Bobby, Hungate, Randall W., Andersen, Neil G., Colyer, John T., Faul, Margaret M., Kamassah, Augustus, Wang, Judy, Jona, Janan, Kumar, Gondi, Johnson, Eileen, Askew, Benny C.

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Aryl sulfones as novel Bradykinin B1 receptor antagonists for treatment of chronic pain von Biswas, Kaustav, Aya, Toshihiro, Qian, Wenyuan, Peterkin, Tanya A.N., Chen, Jian Jeffrey, Human, Jason, Hungate, Randall W., Kumar, Gondi, Arik, Leyla, Lester-Zeiner, Dianna, Biddlecome, Gloria, Manning, Barton H., Sun, Hong, Dong, Hong, Huang, Ming, Loeloff, Richard, Johnson, Eileen J., Askew, Benny C.

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Aryl sulfonamides containing tetralin allylic amines as potent and selective bradykinin B1 receptor antagonists von Liu, Qingyian, Qian, Wenyuan, Li, Aiwen, Biswas, Kaustav, Chen, Jian Jeffrey, Fotsch, Christopher, Han, Nianhe, Yuan, Chester, Arik, Leyla, Biddlecome, Gloria, Johnson, Eileen, Kumar, Gondi, Lester-Zeiner, Dianna, Ng, Gordon Y., Hungate, Randall W., Askew, Benny C.

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Synthesis and evaluation of hydrazinyl-containing pyrrolo[2,3-d]pyrimidine series as potent, selective and oral JAK1 inhibitors for the treatment of rheumatoid arthritis von Mao, Weiwei, Wu, Hao, Guo, Qiang, Zheng, Xuejian, Wei, Changqing, Liao, Yonggang, Shen, Liang, Mi, Jingyu, Li, Jian, Chen, Shuhui, Qian, Wenyuan

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Accelerating Effect of Triazolyl and Related Heteroaryl Substituents on SNAr Reactions: Evidence of Hydrogen-Bond Stabilized Transition States von Qian, Wenyuan, Wang, Hao, Bartberger, Michael D

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Preclinical evaluation of SC0245, a small molecule inhibitor of ATR kinase von Wang, Jian, Li, Qi, Xia, Yuanfeng, Chan, Chi-Chung, Yuan, Xusheng, Wang, Yiwei, Chen, Shuhui, Qian, Wenyuan

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Preclinical evaluation of SC0191, a small molecule inhibitor of Wee1 kinase von Yang, Chundao, Li, Zhengwei, Li, Qi, Xia, Yuanfeng, Chan, Chi-Chung, Yuan, Xusheng, Wang, Yiwei, Chen, Shuhui, Qian, Wenyuan

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Regioselective synthesis of multiply halogenated azaxanthones von Qian, Wenyuan, Brown, James, Chen, Jian Jeffrey, Cheng, Yuan

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Abstract 192: Preclinical evaluation of TQBWX220, a small-molecule inhibitor of IDO1 von Liu, Shilan, Liang, Guibai, Wang, Dahai, Chen, Shuhui, Qian, wenyuan, Chan, Chi-Chung, Zhang, Xiquan, Yang, Lin, Tian, Xin, Gao, Yong, Dong, Tiantian, Liu, Mei, He, Lihua

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Abstract 482: Discovery of a novel and oral CHK1 inhibitor for the treatment of solid tumors von Gao, Xin, Liao, Yonggang, Li, Qi, Yang, Ling, Zhao, Chunyan, Teng, Yanfen, Liu, Lei, Qian, Wenyuan, Yu, Xiaohong

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Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer’s disease von Chen, Jian Jeffrey, Liu, Qingyian, Yuan, Chester, Gore, Vijay, Lopez, Patricia, Ma, Vu, Amegadzie, Albert, Qian, Wenyuan, Judd, Ted C., Minatti, Ana E., Brown, James, Cheng, Yuan, Xue, May, Zhong, Wenge, Dineen, Thomas A., Epstein, Oleg, Human, Jason, Kreiman, Charles, Marx, Isaac, Weiss, Matthew M., Hitchcock, Stephen A., Powers, Timothy S., Chen, Kui, Wen, Paul H., Whittington, Douglas A., Cheng, Alan C., Bartberger, Michael D., Hickman, Dean, Werner, Jonathan A., Vargas, Hugo M., Everds, Nancy E., Vonderfecht, Steven L., Dunn, Robert T., Wood, Stephen, Fremeau, Robert T., White, Ryan D., Patel, Vinod F.

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