Deubiquitination of NLRP3 by BRCC3 Critically Regulates Inflammasome Activity von Py, Bénédicte F., Kim, Mi-Sung, Vakifahmetoglu-Norberg, Helin, Yuan, Junying

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Spotlight on the NLRP3 inflammasome pathway von Groslambert, Marine, Py, Bénédicte F

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Roles of Caspases in Necrotic Cell Death von Yuan, Junying, Najafov, Ayaz, Py, Bénédicte F.

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy von Twig, Gilad, Elorza, Alvaro, Molina, Anthony J A, Mohamed, Hibo, Wikstrom, Jakob D, Walzer, Gil, Stiles, Linsey, Haigh, Sarah E, Katz, Steve, Las, Guy, Alroy, Joseph, Wu, Min, Py, Bénédicte F, Yuan, Junying, Deeney, Jude T, Corkey, Barbara E, Shirihai, Orian S

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Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease von Lipinski, Marta M., Zheng, Bin, Lu, Tao, Yan, Zhenyu, Py, Bénédicte F., Ng, Aylwin, Xavier, Ramnik J., Li, Cheng, Yankner, Bruce A., Scherzer, Clemens R., Yuan, Junying, Greenberg, Michael Eldon

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Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11 von Lagrange, Brice, Benaoudia, Sacha, Wallet, Pierre, Magnotti, Flora, Provost, Angelina, Michal, Fanny, Martin, Amandine, Di Lorenzo, Flaviana, Py, Bénédicte F., Molinaro, Antonio, Henry, Thomas

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Persistent NLRP3 inflammasome activation is associated with delayed immunosuppression in septic patients von Coudereau, Rémy, Bodinier, Maxime, Lukaszewicz, Anne-Claire, F Py, Bénédicte, Argaud, Laurent, Cour, Martin, Bidar, Frank, Cerrato, Elisabeth, Garnier, Lorna, Gossez, Morgane, Venet, Fabienne, Monneret, Guillaume

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NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly von Niu, Tingting, De Rosny, Charlotte, Chautard, Séverine, Rey, Amaury, Patoli, Danish, Groslambert, Marine, Cosson, Camille, Lagrange, Brice, Zhang, Zhirong, Visvikis, Orane, Hacot, Sabine, Hologne, Maggy, Walker, Olivier, Wong, Jeimin, Wang, Ping, Ricci, Roméo, Henry, Thomas, Boyer, Laurent, Petrilli, Virginie, Py, Bénédicte F.

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Caspase-11 controls interleukin-1β release through degradation of TRPC1 von Py, Bénédicte F, Jin, Mingzhi, Desai, Bimal N, Penumaka, Anirudh, Zhu, Hong, Kober, Maike, Dietrich, Alexander, Lipinski, Marta M, Henry, Thomas, Clapham, David E, Yuan, Junying

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Cochlin Produced by Follicular Dendritic Cells Promotes Antibacterial Innate Immunity von Py, Bénédicte F., Gonzalez, Santiago F., Long, Kai, Kim, Mi-Sung, Kim, Young-A., Zhu, Hong, Yao, Jianhua, Degauque, Nicolas, Villet, Régis, Ymele-Leki, Patrick, Gadjeva, Mihaela, Pier, Gerald B., Carroll, Michael C., Yuan, Junying

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Electroporation of mice zygotes with dual guide RNA/Cas9 complexes for simple and efficient cloning-free genome editing von Teixeira, Marie, Py, Bénédicte F., Bosc, Christophe, Laubreton, Daphné, Moutin, Marie-Jo, Marvel, Jacqueline, Flamant, Frédéric, Markossian, Suzy

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A Genome-Wide siRNA Screen Reveals Multiple mTORC1 Independent Signaling Pathways Regulating Autophagy under Normal Nutritional Conditions von Lipinski, Marta M., Hoffman, Greg, Ng, Aylwin, Zhou, Wen, Py, Bénédicte F., Hsu, Emily, Liu, Xuxin, Eisenberg, Jason, Liu, Jun, Blenis, John, Xavier, Ramnik J., Yuan, Junying

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Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors von Cocco, Mattia, Miglio, Gianluca, Giorgis, Marta, Garella, Davide, Marini, Elisabetta, Costale, Annalisa, Regazzoni, Luca, Vistoli, Giulio, Orioli, Marica, Massulaha-Ahmed, Raïhane, Détraz-Durieux, Isabelle, Groslambert, Marine, Py, Bénédicte F., Bertinaria, Massimo

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Familial Mediterranean fever mutations are hypermorphic mutations that specifically decrease the activation threshold of the Pyrin inflammasome von Jamilloux, Yvan, Lefeuvre, Lucie, Magnotti, Flora, Martin, Amandine, Benezech, Sarah, Allatif, Omran, Penel-Page, Mathilde, Hentgen, Véronique, Sève, Pascal, Gerfaud-Valentin, Mathieu, Duquesne, Agnès, Desjonquères, Marine, Laurent, Audrey, Rémy-Piccolo, Vanessa, Cimaz, Rolando, Cantarini, Luca, Bourdonnay, Emilie, Walzer, Thierry, Py, Bénédicte F, Belot, Alexandre, Henry, Thomas

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Autophagy Limits Listeria monocytogenes Intracellular Growth in the Early Phase of Primary Infection von Py, Bénédicte F., Lipinski, Marta M., Yuan, Junying

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IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection von Wallet, Pierre, Benaoudia, Sacha, Mosnier, Amandine, Lagrange, Brice, Martin, Amandine, Lindgren, Helena, Golovliov, Igor, Michal, Fanny, Basso, Pauline, Djebali, Sophia, Provost, Angelina, Allatif, Omran, Meunier, Etienne, Broz, Petr, Yamamoto, Masahiro, Py, Bénédicte F, Faudry, Eric, Sjöstedt, Anders, Henry, Thomas

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Optogenetically controlled inflammasome activation demonstrates two phases of cell swelling during pyroptosis von Nadjar, Julien, Monnier, Sylvain, Bastien, Estelle, Huber, Anne-Laure, Oddou, Christiane, Bardoulet, Léa, Leloup, Hubert B, Ichim, Gabriel, Vanbelle, Christophe, Py, Bénédicte F, Destaing, Olivier, Petrilli, Virginie

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Altered Ex Vivo NLRP3 Inflammasome Activation Is Associated with 28-Day Mortality in Septic Patients von Coudereau, Rémy, Monneret, Guillaume, Lukaszewicz, Anne-Claire, Py, Bénédicte F, Argaud, Laurent, Cour, Martin, Bidar, Frank, Gossez, Morgane, Venet, Fabienne

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Pathogenic variants in the NLRP3 LRR domain at position 861 are responsible for a boost-dependent atypical CAPS phenotype von Fayand, Antoine, Cescato, Margaux, Le Corre, Laurent, Terré, Alexandre, Wacheux, Margaux, Zhu, Yixiang YJ, Melet, Armelle, Moreau, Thomas RJ, Bodaghi, Bahram, Bonnet, Fabrice, Bronnimann, Didier, Cuisset, Laurence, Faria, Raquel, Grateau, Gilles, Pillet, Pascal, Mulders-Manders, Catharina M., Neven, Benedicte, Quartier, Pierre, Richer, Olivier, Savey, Léa, Truchetet, Marie-Elise, Py, Bénédicte F., Boursier, Guilaine, Herbeuval, Jean-Philippe, Georgin-Lavialle, Sophie, Rodero, Mathieu P.

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Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation von Cosson, Camille, Riou, Romane, Patoli, Danish, Niu, Tingting, Rey, Amaury, Groslambert, Marine, De Rosny, Charlotte, Chatre, Elodie, Allatif, Omran, Henry, Thomas, Venet, Fabienne, Milhavet, Florian, Boursier, Guilaine, Belot, Alexandre, Jamilloux, Yvan, Merlin, Etienne, Duquesne, Agnès, Grateau, Gilles, Savey, Léa, Jacques Maria, Alexandre Thibault, Pagnier, Anne, Poutrel, Solène, Lambotte, Olivier, Mallebranche, Coralie, Ardois, Samuel, Richer, Olivier, Lemelle, Irène, Rieux-Laucat, Frédéric, Bader-Meunier, Brigitte, Amoura, Zahir, Melki, Isabelle, Cuisset, Laurence, Touitou, Isabelle, Geyer, Matthias, Georgin-Lavialle, Sophie, Py, Bénédicte F

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