Ric1-Rgp1 Complex Is a Guanine Nucleotide Exchange Factor for the Late Golgi Rab6A GTPase and an Effector of the Medial Golgi Rab33B GTPase von Pusapati, Ganesh V., Luchetti, Giovanni, Pfeffer, Suzanne R.

Volltext

Location, location, and location: compartmentalization of Hedgehog signaling at primary cilia von Pusapati, Ganesh V, Rohatgi, Rajat

Volltext

Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision von Phua, Siew Cheng, Chiba, Shuhei, Suzuki, Masako, Su, Emily, Roberson, Elle C., Pusapati, Ganesh V., Setou, Mitsutoshi, Rohatgi, Rajat, Reiter, Jeremy F., Ikegami, Koji, Inoue, Takanari

Volltext

Cholesterol accessibility at the ciliary membrane controls hedgehog signaling von Kinnebrew, Maia, Iverson, Ellen J, Patel, Bhaven B, Pusapati, Ganesh V, Kong, Jennifer H, Johnson, Kristen A, Luchetti, Giovanni, Eckert, Kaitlyn M, McDonald, Jeffrey G, Covey, Douglas F, Siebold, Christian, Radhakrishnan, Arun, Rohatgi, Rajat

Volltext

EFCAB7 and IQCE Regulate Hedgehog Signaling by Tethering the EVC-EVC2 Complex to the Base of Primary Cilia von Pusapati, Ganesh V., Hughes, Casey E., Dorn, Karolin V., Zhang, Dapeng, Sugianto, Priscilla, Aravind, L., Rohatgi, Rajat

Volltext

G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog von Pusapati, Ganesh V, Kong, Jennifer H, Patel, Bhaven B, Gouti, Mina, Sagner, Andreas, Sircar, Ria, Luchetti, Giovanni, Ingham, Philip W, Briscoe, James, Rohatgi, Rajat

Volltext

R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling von Dubey, Ramin, van Kerkhof, Peter, Jordens, Ingrid, Malinauskas, Tomas, Pusapati, Ganesh V, McKenna, Joseph K, Li, Dan, Carette, Jan E, Ho, Mitchell, Siebold, Christian, Maurice, Madelon, Lebensohn, Andres M, Rohatgi, Rajat

Volltext

Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling von Hong, Shi-Rong, Wang, Cuei-Ling, Huang, Yao-Shen, Chang, Yu-Chen, Chang, Ya-Chu, Pusapati, Ganesh V., Lin, Chun-Yu, Hsu, Ning, Cheng, Hsiao-Chi, Chiang, Yueh-Chen, Huang, Wei-En, Shaner, Nathan C., Rohatgi, Rajat, Inoue, Takanari, Lin, Yu-Chun

Volltext

Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength von Kong, Jennifer H, Young, Cullen B, Pusapati, Ganesh V, Espinoza, F Hernán, Patel, Chandni B, Beckert, Francis, Ho, Sebastian, Patel, Bhaven B, Gabriel, George C, Aravind, L, Bazan, J Fernando, Gunn, Teresa M, Lo, Cecilia W, Rohatgi, Rajat

Volltext

Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling von Bosakova, Michaela, Abraham, Sara P, Nita, Alexandru, Hruba, Eva, Buchtova, Marcela, Taylor, S Paige, Duran, Ivan, Martin, Jorge, Svozilova, Katerina, Barta, Tomas, Varecha, Miroslav, Balek, Lukas, Kohoutek, Jiri, Radaszkiewicz, Tomasz, Pusapati, Ganesh V, Bryja, Vitezslav, Rush, Eric T, Thiffault, Isabelle, Nickerson, Deborah A, Bamshad, Michael J, Rohatgi, Rajat, Cohn, Daniel H, Krakow, Deborah, Krejci, Pavel

Volltext

Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens von Patel, Bhaven B, Lebensohn, Andres M, Pusapati, Ganesh V, Carette, Jan E, Salzman, Julia, Rohatgi, Rajat

Volltext

CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog von Pusapati, Ganesh V., Kong, Jennifer H., Patel, Bhaven B., Krishnan, Arunkumar, Sagner, Andreas, Kinnebrew, Maia, Briscoe, James, Aravind, L., Rohatgi, Rajat

Volltext

Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity von Carmi, Yaron, Spitzer, Matthew H., Linde, Ian L., Burt, Bryan M., Prestwood, Tyler R., Perlman, Nicola, Davidson, Matthew G., Kenkel, Justin A., Segal, Ehud, Pusapati, Ganesh V., Bhattacharya, Nupur, Engleman, Edgar G.

Volltext

Protein kinase D2 is an essential regulator of murine myoblast differentiation von Kleger, Alexander, Loebnitz, Christiane, Pusapati, Ganesh V, Armacki, Milena, Müller, Martin, Tümpel, Stefan, Illing, Anett, Hartmann, Daniel, Brunner, Cornelia, Liebau, Stefan, Rudolph, Karl L, Adler, Guido, Seufferlein, Thomas

Volltext

An essential role for Grk2 in Hedgehog signalling downstream of Smoothened von Zhao, Zhonghua, Lee, Raymond Teck Ho, Pusapati, Ganesh V, Iyu, Audrey, Rohatgi, Rajat, Ingham, Philip W

Volltext

Regulated N-glycosylation controls chaperone function and receptor trafficking von Ma, Mengxiao, Dubey, Ramin, Jen, Annie, Pusapati, Ganesh V, Singal, Bharti, Shishkova, Evgenia, Overmyer, Katherine A, Cormier-Daire, Valérie, Fedry, Juliette, Aravind, L, Coon, Joshua J, Rohatgi, Rajat

Volltext

A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development von Kong, Jennifer H., Young, Cullen B., Pusapati, Ganesh V., Patel, Chandni B., Ho, Sebastian, Krishnan, Arunkumar, Lin, Jiuann-Huey Ivy, Devine, William, Moreau de Bellaing, Anne, Athni, Tejas S., Aravind, L., Gunn, Teresa M., Lo, Cecilia W., Rohatgi, Rajat

Volltext

CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog von Pusapati, Ganesh V., Kong, Jennifer H., Patel, Bhaven B., Krishnan, Arunkumar, Sagner, Andreas, Kinnebrew, Maia, Briscoe, James, Aravind, L., Rohatgi, Rajat

Volltext

Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision von Phua, Siew Cheng, Chiba, Shuhei, Suzuki, Masako, Su, Emily, Roberson, Elle C., Pusapati, Ganesh V., Schurmans, Stéphane, Setou, Mitsutoshi, Rohatgi, Rajat, Reiter, Jeremy F., Ikegami, Koji, Inoue, Takanari

Volltext

Protein Kinase D Regulates RhoA Activity via Rhotekin Phosphorylation von Pusapati, Ganesh V., Eiseler, Tim, Rykx, An, Vandoninck, Sandy, Derua, Rita, Waelkens, Etienne, Van Lint, Johan, von Wichert, Götz, Seufferlein, Thomas

Volltext