Annexin-A1: Therapeutic Potential in Microvascular Disease von Purvis, Gareth S D, Solito, Egle, Thiemermann, Christoph

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Inhibition of Bruton's TK regulates macrophage NF‐κB and NLRP3 inflammasome activation in metabolic inflammation von Purvis, Gareth S.D., Collino, Massimo, Aranda‐Tavio, Haidee, Chiazza, Fausto, O'Riordan, Caroline E., Zeboudj, Lynda, Mohammad, Shireen, Collotta, Debora, Verta, Roberta, Guisot, Nicolas E.S., Bunyard, Peter, Yaqoob, Magdi M., Greaves, David R., Thiemermann, Christoph

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Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages von Recio, Carlota, Lucy, Daniel, Purvis, Gareth S D, Iveson, Poppy, Zeboudj, Lynda, Iqbal, Asif J, Lin, Daniel, O'Callaghan, Chris, Davison, Lucy, Griesbach, Esther, Russell, Angela J, Wynne, Graham M, Dib, Lea, Monaco, Claudia, Greaves, David R

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Bruton's TK regulates myeloid cell recruitment during acute inflammation von Purvis, Gareth S. D., Aranda‐Tavio, Haidee, Channon, Keith M., Greaves, David R.

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A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages von Lucy, Daniel, Purvis, Gareth S. D, Zeboudj, Lynda, Chatzopoulou, Maria, Recio, Carlota, Bataille, Carole J. R, Wynne, Graham M, Greaves, David R, Russell, Angela J

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Impact of metabolic disorders on the structural, functional, and immunological integrity of the blood‐brain barrier: Therapeutic avenues von Sheikh, Madeeha H., Errede, Mariella, d'Amati, Antonio, Khan, Noorafza Q., Fanti, Silvia, Loiola, Rodrigo A., McArthur, Simon, Purvis, Gareth S. D., O'Riordan, Caroline E., Ferorelli, Davide, Dell'Erba, Alessandro, Kieswich, Julius, Reutelingsperger, Chis, Maiorano, Eugenio, Yaqoob, Magdi, Thiemermann, Christoph, Baragetti, Andrea, Catapano, Alberico Luigi, Norata, Giuseppe Danilo, Marelli‐Berg, Federica, Virgintino, Daniela, Solito, Egle

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Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes von Purvis, Gareth S. D., Chiazza, Fausto, Chen, Jianmin, Azevedo-Loiola, Rodrigo, Martin, Lukas, Kusters, Dennis H. M., Reutelingsperger, Chris, Fountoulakis, Nikolaos, Gnudi, Luigi, Yaqoob, Muhammed M., Collino, Massimo, Thiemermann, Christoph, Solito, Egle

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RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance von Chen, Jianmin, Purvis, Gareth S D, Collotta, Debora, Al Zoubi, Sura, Sugimoto, Michelle A, Cacace, Antonino, Martin, Lukas, Colas, Roman A, Collino, Massimo, Dalli, Jesmond, Thiemermann, Christoph

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Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice von O'Riordan, Caroline E, Purvis, Gareth S D, Collotta, Debora, Chiazza, Fausto, Wissuwa, Bianka, Al Zoubi, Sura, Stiehler, Lara, Martin, Lukas, Coldewey, Sina M, Collino, Massimo, Thiemermann, Christoph

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Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes von Purvis, Gareth S D, Collino, Massimo, Loiola, Rodrigo A, Baragetti, Andrea, Chiazza, Fausto, Brovelli, Martina, Sheikh, Madeeha H, Collotta, Debora, Cento, Alessia, Mastrocola, Raffaella, Aragno, Manuela, Cutrin, Juan C, Reutelingsperger, Chris, Grigore, Liliana, Catapano, Alberico L, Yaqoob, Magdi M, Norata, Giuseppe Danilo, Solito, Egle, Thiemermann, Christoph

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A Human CD68 Promoter-Driven Inducible Cre-Recombinase Mouse Line Allows Specific Targeting of Tissue Resident Macrophages von Rumianek, Agata N, Davies, Ben, Channon, Keith M, Greaves, David R, Purvis, Gareth S D

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X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure von O'Riordan, Caroline E, Purvis, Gareth S D, Collotta, Debora, Krieg, Nadine, Wissuwa, Bianka, Sheikh, Madeeha H, Ferreira Alves, Gustavo, Mohammad, Shireen, Callender, Lauren A, Coldewey, Sina M, Collino, Massimo, Greaves, David R, Thiemermann, Christoph

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IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD von Chen, Jianmin, Kieswich, Julius E, Chiazza, Fausto, Moyes, Amie J, Gobbetti, Thomas, Purvis, Gareth S D, Salvatori, Daniela C F, Patel, Nimesh S A, Perretti, Mauro, Hobbs, Adrian J, Collino, Massimo, Yaqoob, Muhammad M, Thiemermann, Christoph

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Drug repurposing screen identifies novel anti-inflammatory activity of sunitinib in macrophages von Chaffey, Laura E., Roberti, Annabell, Bowman, Amelia, O'Brien, Conan JO, Som, Liliana, Purvis, Gareth SD, Greaves, David R.

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Novel Synthetic, Host-defense Peptide Protects Against Organ Injury/Dysfunction in a Rat Model of Severe Hemorrhagic Shock von Yamada, Noriaki, Martin, Lukas B, Zechendorf, Elisabeth, Purvis, Gareth S D, Chiazza, Fausto, Varrone, Barbara, Collino, Massimo, Shepherd, Joanna, Heinbockel, Lena, Gutsmann, Thomas, Correa, Wilmar, Brandenburg, Klaus, Marx, Gernot, Schuerholz, Tobias, Brohi, Karim, Thiemermann, Christoph

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A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice von Mohammad, Shireen, Al Zoubi, Sura, Collotta, Debora, Krieg, Nadine, Wissuwa, Bianka, Ferreira Alves, Gustavo, Purvis, Gareth S D, Norata, Giuseppe Danilo, Baragetti, Andrea, Catapano, Alberico Luigi, Solito, Egle, Zechendorf, Elisabeth, Schürholz, Tobias, Correa-Vargas, Wilmar, Brandenburg, Klaus, Coldewey, Sina M, Collino, Massimo, Yaqoob, Muhammad M, Martin, Lukas, Thiemermann, Christoph

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OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity von Purvis, Gareth S D, Collino, Massimo, van Dam, Andrea D, Einaudi, Giacomo, Ng, Yujung, Shanmuganathan, Mayooran, Patel, Smita Y, Thiemermann, Christoph, Channon, Keith M, Greaves, David R

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Ly6Chi Monocytes Are Metabolically Reprogrammed in the Blood during Inflammatory Stimulation and Require Intact OxPhos for Chemotaxis and Monocyte to Macrophage Differentiation von Purvis, Gareth S. D., McNeill, Eileen, Wright, Benjamin, Channon, Keith M., Greaves, David R.

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Efferocytosis perpetuates substance accumulation inside macrophage populations von Ford, Hugh Z, Zeboudj, Lynda, Purvis, Gareth S D, Ten Bokum, Annemieke, Zarebski, Alexander E, Bull, Joshua A, Byrne, Helen M, Myerscough, Mary R, Greaves, David R

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Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis von Johnson, Florence L., Patel, Nimesh S. A., Purvis, Gareth S. D., Chiazza, Fausto, Chen, Jianmin, Sordi, Regina, Hache, Guillaume, Merezhko, Viktoria V., Collino, Massimo, Yaqoob, Muhammed M., Thiemermann, Christoph

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